Výsledky vyhledávání - "S S Chaudhaery"

Molecular modelling and docking studies on heat shock protein 90 (Hsp90) inhibitors

Autor: S S Chaudhaery, A K Saxena, Shailendra K. Saxena

Publikováno v: SAR and QSAR in Environmental Research. 21:1-20

An adenosine tri-phosphate (ATP)-dependent molecular chaperone heat shock protein (Hsp90) is of current interest as a potential anticancer drug target. It has several oncogenic client proteins involved in signal transduction, cell cycle regulation an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f96cd293848c5186703862f42c2c9c7
https://doi.org/10.1080/10629360903560504

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Pharmacophore-based virtual screening and docking studies on Hsp90 inhibitors

Autor: S S Chaudhaery, Shailendra K. Saxena, A K Saxena, Kanika Varshney

Publikováno v: SAR and QSAR in environmental research. 21(5-6)

Hsp90 (Heat shock protein 90) is an important therapeutic target for the treatment of cancer. To identify important chemical features for Hsp90 inhibitory activity, a 3D-QSAR pharmacophore model was developed using a set of 61 inhibitors (a training

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5c80d5ceef989c65095169b717b481
https://pubmed.ncbi.nlm.nih.gov/20818581

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