Zobrazeno 1 - 10
of 44
pro vyhledávání: '"S S, Zoghbi"'
Publikováno v:
ChemInform. 27
Autor:
J C, Soares, C H, van Dyck, P, Tan, S S, Zoghbi, P, Garg, R, Soufer, R M, Baldwin, M, Fujita, J K, Staley, X, Fu, L, Amici, J, Seibyl, R B, Innis
Publikováno v:
Psychiatry research. 106(2)
The test/retest reproducibility of brain measures of 5-HT2A receptors with positron emission tomography (PET) and [18F]deuteroaltanserin was examined in a group of eight healthy human subjects. PET measures of 5-HT2A receptors were obtained under an
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(9)
Nicotinic acetylcholine receptors (nAChRs) play an important role in tobacco dependence and a potential therapeutic role in neuropsychiatric disorders such as Alzheimer's disease. [123I]5-iodo-3-[2(S)-2-azetidinylmethoxy]pyridine (5-I-A-85380) is a n
Autor:
A, Varrone, M, Fujita, N P, Verhoeff, S S, Zoghbi, R M, Baldwin, N, Rajeevan, D S, Charney, J P, Seibyl, R B, Innis
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(8)
This study evaluated the test-retest reproducibility of D2 receptor quantification in the thalamus and temporal cortex using [123I]epidepride SPECT.Ten healthy volunteers (4 men, 6 women; age range, 19-46 y) underwent 2 SPECT studies (interval, 2-26
Autor:
B E, Scanley, M S, Gandelman, M, Laruelle, M S, Al-Tikriti, R M, Baldwin, S S, Zoghbi, P B, Hoffer, S, Wang, J L, Neumeyer, R B, Innis
Publikováno v:
Nuclear medicine and biology. 27(1)
[123I]2beta-carbomethoxy-3beta-(4-iodophenyl)tropane ([123I]-CIT) and its isopropylester analog [123I]PCIT, both of which are phenyltropane derivatives of cocaine with high affinity for the dopamine (DA) transporter, were compared using single photon
Autor:
M, Ichise, M, Fujita, J P, Seibyl, N P, Verhoeff, R M, Baldwin, S S, Zoghbi, N, Rajeevan, D S, Charney, R B, Innis
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 40(11)
The purpose of this study was to extend the graphical analysis of reversible tracer binding to account for labeled lipophilic metabolites (metabolites) in quantifying [123I]epidepride binding to striatal and extrastriatal D2 receptors and, additional
Autor:
M, Fujita, J P, Seibyl, N P, Verhoeff, M, Ichise, R M, Baldwin, S S, Zoghbi, C, Burger, J K, Staley, N, Rajeevan, D S, Charney, R B, Innis
Publikováno v:
Synapse (New York, N.Y.). 34(4)
Quantitative SPECT measures of dopamine D(2) like receptors with [(123)I]epidepride is complicated by its high affinity and lipophilic metabolites. The purpose of this study was to use both parent (P) and lipophilic metabolites (M) as input functions
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(10)
The purposes of this study were to develop a method for nonuniform attenuation correction of 123I emission brain images based on transmission imaging with a longer-lived isotope (i.e., 57Co) and to evaluate the relative improvement in quantitative SP
Autor:
M, Laruelle, R N, Iyer, M S, al-Tikriti, Y, Zea-Ponce, R, Malison, S S, Zoghbi, R M, Baldwin, H F, Kung, D S, Charney, P B, Hoffer, R B, Innis, C W, Bradberry
Publikováno v:
Synapse (New York, N.Y.). 25(1)
The competition between endogenous transmitters and radiolabeled ligands for in vivo binding to neuroreceptors might provide a method to measure endogenous transmitter release in the living human brain with noninvasive techniques such as positron emi
Autor:
M, Laruelle, A, Abi-Dargham, C H, van Dyck, W, Rosenblatt, Y, Zea-Ponce, S S, Zoghbi, R M, Baldwin, D S, Charney, P B, Hoffer, H F, Kung
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 36(7)
This study assesses the feasibility of using SPECT to image intrasynaptic dopamine release in human striatum following dextroamphetamine sulfate (d-amphetamine) challenge testing.A bolus plus constant infusion administration schedule of the D2 recept