Zobrazeno 1 - 10
of 65
pro vyhledávání: '"S S, Simons"'
Autor:
S. S. Simons
Publikováno v:
Molecular Endocrinology. 6:995-1002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee378f25ed4d20e91f5cf237b63eb00e
https://doi.org/10.1210/me.6.7.995
https://doi.org/10.1210/me.6.7.995
Publikováno v:
The Journal of Immunology. 145:4037-4045
Both cellular activation signals and exposure to glucocorticoids such as dexamethasone (Dex) cause programmed cell death in T cell hybridomas. When cells were activated in the presence of Dex, however, the degree of killing that was achieved by eithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced762b1864264797db7d6a7b20765d9
https://doi.org/10.4049/jimmunol.145.12.4037
https://doi.org/10.4049/jimmunol.145.12.4037
Publikováno v:
The Journal of biological chemistry. 276(27)
A major unanswered question of glucocorticoid and progesterone action is how different whole cell responses arise when both of the cognate receptors can bind to, and activate, the same hormone response elements. We have documented previously that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2da2e13ac2ad70f38884bb7c3d0d4ddd
https://pubmed.ncbi.nlm.nih.gov/11333273
https://pubmed.ncbi.nlm.nih.gov/11333273
Publikováno v:
Molecular and cellular endocrinology. 155(1-2)
Steroid-induced changes in receptor protein conformation constitute a logical means of translating the variations in steroid structures into the observed array of whole cell biological activities. One conformational change in the rat glucocorticoid r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c71336715a0d7876e6bbe7363ece8a88
https://pubmed.ncbi.nlm.nih.gov/10580842
https://pubmed.ncbi.nlm.nih.gov/10580842
Publikováno v:
The Journal of biological chemistry. 271(35)
A long-standing conundrum of glucocorticoid receptors has been why the steroid binding domain is active in hybrid proteins but not in isolation. For this reason, the precise boundaries of the steroid binding domain have not been defined. These questi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef92935eface08255de8721654ab2fbf
https://pubmed.ncbi.nlm.nih.gov/8702925
https://pubmed.ncbi.nlm.nih.gov/8702925
Autor:
S S, Simons, W B, Pratt
Publikováno v:
Methods in enzymology. 251
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8af9c27069a9e07c0e71d94589c059af
https://pubmed.ncbi.nlm.nih.gov/7651222
https://pubmed.ncbi.nlm.nih.gov/7651222
Publikováno v:
The Journal of biological chemistry. 269(41)
The ability of sodium molybdate, both to stabilize the steroid binding activity of glucocorticoid receptors and to prevent the activation of receptor-steroid complexes to a DNA binding species, has long been thought to involve thiols. Two receptor th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62bf6c8627389551a8873be61e1a4cbf
https://pubmed.ncbi.nlm.nih.gov/7929266
https://pubmed.ncbi.nlm.nih.gov/7929266
Autor:
J, Opoku, S S, Simons
Publikováno v:
The Journal of biological chemistry. 269(1)
The presence of intramolecular disulfides in different functional states of the native glucocorticoid receptor in the absence of added oxidants has been examined on nonreducing SDS-polyacrylamide gels. Possible disulfides were trapped by the reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5afaf831b33123ba06726912a0321d93
https://pubmed.ncbi.nlm.nih.gov/8276843
https://pubmed.ncbi.nlm.nih.gov/8276843
Autor:
H, Oshima, S S, Simons
Publikováno v:
The Journal of biological chemistry. 268(36)
Synergism in transcription is said to occur when the combined response from two DNA elements for the binding of trans-acting factors is greater than the sum of the responses from each element in isolation. The synergism of steroid receptors with them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3d0b0528b0dd6db34d6a9abbc4bd380
https://pubmed.ncbi.nlm.nih.gov/7903299
https://pubmed.ncbi.nlm.nih.gov/7903299
Publikováno v:
The Journal of biological chemistry. 267(16)
The involvement of a vicinally spaced dithiol group in steroid binding to the glucocorticoid receptor has been deduced from experiments with the thiol-specific reagent methyl methanethiolsulfonate and the vicinal dithiol-specific reagent sodium arsen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d773fb9a6275d2e715d6ed8f481da74c
https://pubmed.ncbi.nlm.nih.gov/1597467
https://pubmed.ncbi.nlm.nih.gov/1597467