Zobrazeno 1 - 10
of 275
pro vyhledávání: '"S S, Ozturk"'
Autor:
S. S. Ozturk, Parisa Jorjani
Publikováno v:
Biotechnology and Bioengineering. 64:349-356
Oxygen consumption rates were measured in a respirometer for different mammalian cell lines (BHK, murine hybridoma, and CHO), and the effects of cell density (1-20 million cells/mL) and temperature (6 to 37 degrees C) on specific oxygen consumption r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::078e312513e78daccb1751b0b3f9653d
https://doi.org/10.1002/(sici)1097-0290(19990805)64:3<349::aid-bit11>3.0.co
https://doi.org/10.1002/(sici)1097-0290(19990805)64:3<349::aid-bit11>3.0.co
Publikováno v:
Biotechnology and Bioengineering. 48:201-206
On-line, “real-time” monitoring of product concentration is important for mammalian cell culture fermentation. The continuous measurement of monoclonal antibodies allows for instantaneous determination of cell productivity and effective manipulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2401f4cc1c998704fbb411df376ca868
https://doi.org/10.1002/bit.260480306
https://doi.org/10.1002/bit.260480306
Publikováno v:
Biotechnology and Bioengineering. 45:495-502
On-line optical cell density probes were implemented to continuously monitor the cell densities in mammalian cell bioreactor and to achieve advanced bioreactor controls. We tested cell density probes from six manufacturers in high cell density biorea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc808dc717b34de91910e4db98de9b7e
https://doi.org/10.1002/bit.260450606
https://doi.org/10.1002/bit.260450606
Autor:
S. S. Ozturk
Publikováno v:
Cytotechnology. 22(1-3)
High density cell culture systems offer the advantage of production of bio-pharmaceuticals in compact bioreactors with high volumetric production rates; however, these systems are difficult to design and operate. First of all, the cells have to be re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df88b9c9758e8f49ff4a3270ee6399bf
https://pubmed.ncbi.nlm.nih.gov/22358910
https://pubmed.ncbi.nlm.nih.gov/22358910
Autor:
S. S. Ozturk
Publikováno v:
Encyclopedia of Bioprocess Technology
Introduction Sources of Ammonia Accumulation Generation of Ammonia Caused by Glutamine Degradation Generation of Ammonia Caused by Cell Metabolism Effects of Ammonia on Cell Physiology Effects of Ammonia on Cell Growth Effects of Ammonia on Cell Deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a4ecf540e71df07d05c6b6568ddd11f
https://doi.org/10.1002/0471250589.ebt013
https://doi.org/10.1002/0471250589.ebt013
Autor:
P, Jorjani, S S, Ozturk
Publikováno v:
Biotechnology and bioengineering. 64(3)
Oxygen consumption rates were measured in a respirometer for different mammalian cell lines (BHK, murine hybridoma, and CHO), and the effects of cell density (1-20 million cells/mL) and temperature (6 to 37 degrees C) on specific oxygen consumption r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1d1aa6f392a48ab2ed5e03531401572
https://pubmed.ncbi.nlm.nih.gov/10397872
https://pubmed.ncbi.nlm.nih.gov/10397872
Publikováno v:
Biotechnology and bioengineering. 53(4)
On-line monitoring and control of cell culture fermentation is important for optimal and consistent production of biologicals. In this work, glucose and lactate concentrations are monitored on-line using a commercially available analyzer (Model 2700,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe1350f3ee5f62ba8bf6a5221448167f
https://pubmed.ncbi.nlm.nih.gov/18634025
https://pubmed.ncbi.nlm.nih.gov/18634025
On-Line Monitoring for Consistent and Optimal Production of Biologicals from Mammalian Cell Cultures
Autor:
Konstantin Konstantinov, Yeong-shou Tsai, R. Taticek, S. S. Ozturk, J. D. Blackie, David Naveh, John Thrift, P. Wu, Cary Matanguihan, S. Yoon
Publikováno v:
Animal Cell Technology ISBN: 9789401062732
Despite all efforts, process monitoring and control of mammalian cell cultures are still limited to physical variables such as pH, DO, and temperature. Although these are important parameters, cellular activities are equally governed by the biochemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7341548ecb224cb97061ef4bc43d9d3b
https://doi.org/10.1007/978-94-011-5404-8_33
https://doi.org/10.1007/978-94-011-5404-8_33
Autor:
B. Lowe, D. Ladehoff-Guiles, S. S. Ozturk, S. Shackleford, R. Taticek, David Naveh, J. D. Blackie, John Thrift, P. Jorjani
Publikováno v:
Animal Cell Technology ISBN: 9789401062732
Glucose is a major energy source for mammalian cells grown in culture. Although conditions are aerobic, in most cases, glucose is not completely oxidized. Depending on the culture conditions and the cell type, about 50-100% of glucose is converted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cf41b4bf6a86dd365520d0577fb97f4
https://doi.org/10.1007/978-94-011-5404-8_56
https://doi.org/10.1007/978-94-011-5404-8_56
Publikováno v:
Animal Cell Technology: Developments Towards the 21st Century ISBN: 9789401041959
A perfusion bioreactor system has been developed for independent control of cell density and metabolite concentrations. The cell density was monitored and controlled using an online optical sensor. A constant environment to the cell was provided by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eae80d5e6984bd3bab68280b7d87109
https://doi.org/10.1007/978-94-011-0437-1_47
https://doi.org/10.1007/978-94-011-0437-1_47