Zobrazeno 1 - 10
of 171
pro vyhledávání: '"S S, Leonard"'
Autor:
C, Huang, J, Li, M, Costa, Z, Zhang, S S, Leonard, V, Castranova, V, Vallyathan, G, Ju, X, Shi
Publikováno v:
Cancer research. 61(22)
Nickel compounds induce cell transformation in cell culture models and tumor formation in experimental animals. However, the molecular mechanisms by which nickel compounds induce tumors are not yet well understood. The present study found that exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::820e642a1b9665be71703a6ce120227c
https://pubmed.ncbi.nlm.nih.gov/11719426
https://pubmed.ncbi.nlm.nih.gov/11719426
Publikováno v:
Molecular and cellular biochemistry. 222(1-2)
Cr (VI) compounds are widely used in industries and are recognized human carcinogens. The mechanism of carcinogenesis associated with these compounds is not well understood. The present study focused on Cr (VI)-induced cell growth arrest in human lun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c0a4e80f013cccab30198e2a4c6224f
https://pubmed.ncbi.nlm.nih.gov/11678614
https://pubmed.ncbi.nlm.nih.gov/11678614
On the mechanism of Cr (VI)-induced carcinogenesis: dose dependence of uptake and cellular responses
Autor:
K, Liu, J, Husler, J, Ye, S S, Leonard, D, Cutler, F, Chen, S, Wang, Z, Zhang, M, Ding, L, Wang, X, Shi
Publikováno v:
Molecular and cellular biochemistry. 222(1-2)
Cr (VI) compounds are widely used industrial chemicals and are recognized human carcinogens. The mechanisms of carcinogenesis associated with these compounds remain to be investigated. The present study focused on dose-dependence of Cr (VI)-induced u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39e04bd7c19caedbe9a903d849f64dd7
https://pubmed.ncbi.nlm.nih.gov/11678606
https://pubmed.ncbi.nlm.nih.gov/11678606
Autor:
Y, Qian, B H, Jiang, D C, Flynn, S S, Leonard, S, Wang, Z, Zhang, J, Ye, F, Chen, L, Wang, X, Shi
Publikováno v:
Molecular and cellular biochemistry. 222(1-2)
While Cr (VI)-containing compounds are well established carcinogens, the mechanisms of their action remain to be investigated. In this study we show that Cr (VI) causes increased tyrosine phosphorylation in human lung epithelial A549 cells in a time-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4a554e8b08adc958a8f5eb8ffc21b4d
https://pubmed.ncbi.nlm.nih.gov/11678602
https://pubmed.ncbi.nlm.nih.gov/11678602
Publikováno v:
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 19(3)
Epidemiological studies demonstrate that environmental and occupational exposure of chromium(VI) [Cr(VI)] or Cr(VI)-containing particles can cause a number of human diseases, including inflammation and cancer. The biological mechanisms responsible fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77917a992e753d1ed4b0f98139f1ac3d
https://pubmed.ncbi.nlm.nih.gov/10983889
https://pubmed.ncbi.nlm.nih.gov/10983889
Publikováno v:
Molecular and cellular biochemistry. 206(1-2)
Electron spin resonance (ESR) spin trapping was utilized to investigate the scavenging effects on hydroxyl radicals (*OH) and superoxide radicals (O2*-) by (-)-epigallocatechin-3-gallate (EGCG), one of the major anticancer compounds in tea. The spin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4e17cf0a9fe979f8adbd8e39a550bc3
https://pubmed.ncbi.nlm.nih.gov/10839202
https://pubmed.ncbi.nlm.nih.gov/10839202
Publikováno v:
Annals of clinical and laboratory science. 30(2)
Pyrrolidine dithiocarbamate (PDTC) is considered an antioxidant and is frequently used to study the role of free radical reactions in various biological processes and against free radical-induced cellular injuries. However, its antioxidant properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b44335f8fbf8f6cfb272d092cea1c77b
https://pubmed.ncbi.nlm.nih.gov/10807167
https://pubmed.ncbi.nlm.nih.gov/10807167
Autor:
J, Ye, M, Ding, S S, Leonard, V A, Robinson, L, Millecchia, X, Zhang, V, Castranova, V, Vallyathan, X, Shi
Publikováno v:
Molecular and cellular biochemistry. 202(1-2)
Apoptosis is a physiological mechanism for the control of DNA integrity in mammalian cells. Vanadium induces both DNA damage and apoptosis. It is suggested that vanadium-induced apoptosis serves to eliminate DNA-damaged cells. This study is designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf54f11e75c931f49f6000839891210c
https://pubmed.ncbi.nlm.nih.gov/10705990
https://pubmed.ncbi.nlm.nih.gov/10705990
Autor:
X, Shi, M, Ding, Z, Dong, F, Chen, J, Ye, S, Wang, S S, Leonard, V, Castranova, V, Vallyathan
Publikováno v:
Molecular and cellular biochemistry. 199(1-2)
Electron spin resonance (ESR) was used to investigate the reaction of aspirin toward reactive oxygen species, such as hydroxyl radicals (*OH), superoxide radicals (O2-) and H2O2. The Fenton reaction (Fe(II) + H2O2 ---FE(III) + *OH + OR) was used as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4090c51b809080fde0b728602c81f863
https://pubmed.ncbi.nlm.nih.gov/10544957
https://pubmed.ncbi.nlm.nih.gov/10544957
Publikováno v:
Annals of clinical and laboratory science. 29(3)
Electron spin resonable (ESR) spin trapping with 5-(diethioxyphosphoyl)-5-methyl-1-pyrroline N-oxide (DEPMPO) was utilized to investigate the generation of oxygen free radicals from macrophages stimulated by tumor necrosis factor-alpha (TNF-alpha). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c06d9e667119efe2fcfce5edba295586
https://pubmed.ncbi.nlm.nih.gov/10440583
https://pubmed.ncbi.nlm.nih.gov/10440583