Zobrazeno 1 - 10
of 114
pro vyhledávání: '"S S, Legha"'
Autor:
Jeffrey E. Lee, Wen-Jen Hwu, Rene Gonzalez, Agop Y. Bedikian, Omar Eton, Patrick Hwu, Ping Liu, Carl Plager, Kevin B. Kim, Marcella M. Johnson, Antonio C. Buzaid, Angela M. Frost, Robert S. Benjamin, Jeffrey E. Gershenwald, Victor G. Prieto, Paul F. Mansfield, Nicholas E. Papadopoulos, Clay M. Anderson, Merrick I. Ross, Gladys Alvarado, S. S. Legha
Publikováno v:
Melanoma Research. 19:42-49
The objective of this study was to compare the clinical benefit of biochemotherapy and interferon-alpha-2b (IFN) as adjuvant therapy. Biochemotherapy has higher response rates than other regimens in patients with metastatic melanoma. We conducted a r
Autor:
Omar Eton, Antonio Buzaid, R N Mary Jo East, Michael G. Rosenblum, S. S. Legha, Wehei Zhang, Nicholas Papadopoulos, Agop Bedikian, Robert S. Benjamin
Publikováno v:
Cancer. 95:127-134
BACKGROUND Interleukin-2 (IL-2) has activity in metastatic melanoma when given in high doses by the intravenous (IV) route, but its side effects and effectiveness when given in intermediate to high doses by the subcutaneous (SC) route have not been s
Autor:
Diane Bodurka-Bevers, Claire F. Verschraegen, W. Supakarapongkul, Lawrence B. Levy, Edward N. Atkinson, Mongkol Benjapibal, Andrzej P. Kudelka, John J. Kavanagh, S. S. Legha, Merrick I. Ross
Publikováno v:
International Journal of Gynecological Cancer. 11:359-364
The purpose of this study was to review the clinical course of patients diagnosed with vulvar melanoma. Charts of patients diagnosed between 1970 and 1997 were reviewed for demographics, lesion characteristics, disease duration and extent, and treatm
Autor:
M R N Teresa Smith, Julie A. Ellerhorst, Antonio C. Buzaid, Agop Y. Bedikian, S. S. Legha, L R N Janelle Hibberts, Nicholas E. Papadopoulos, Omar Eton, Robert S. Benjamin
Publikováno v:
Cancer. 88:1703-1709
BACKGROUND The authors tested a biotherapy regimen involving recombinant interferon-α-2a (rIFN-α-2a) and recombinant human interleukin-2 (rhIL-2), given in a “decrescendo” schedule over 5 days, for its activity and toxicity in 21 patients who p
Publikováno v:
Melanoma Research. 9:575-582
In order to evaluate the natural history, prognostic parameters and treatment modalities for metastatic uveal melanoma, a review of the clinical data from the current literature was performed based on a Medline database search. Uveal melanoma represe
Autor:
S. S. Legha, Viallet J, Nicholas E. Papadopoulos, Carl Plager, Agop Y. Bedikian, Antonio C. Buzaid, Omar Eton, Susan McIntyre
Publikováno v:
Anti-Cancer Drugs. 10:735-740
A phase II study was undertaken to determine the efficacy of tirapazamine combined with cisplatin in patients with metastatic melanoma between April 1996 and April 1997. Tirapazamine 390 mg/m2, administered i.v. over 2 h, followed in 1 h by cisplatin
Autor:
S. Coates, Omar Eton, R. von Roemeling, A. C. Buzaid, T. Simmons, N. Papadopoulos, A. Y. Bedikian, J. Neefe, S. S. Legha
Publikováno v:
Annals of Oncology. 8:363-367
Summary Purpose A phase II study was undertaken to determine the efficacy of tirapazamine (TPZ) combined with cisplatin (cDDP) in patients with metastatic melanoma. Patients and methods Between June 1994 and November 1995, 48 patients with metastatic
Autor:
Howard A. Burris, J R Eckardt, J Jenkins, Geoffrey R. Weiss, S. S. Legha, Agop Y. Bedikian, Omar Eton, D. D. Von Hoff, L Smetzer, Antonio C. Buzaid
Publikováno v:
Journal of Clinical Oncology. 13:2895-2899
PURPOSE A phase II study was undertaken to determine the efficacy of docetaxel in patients with metastatic malignant melanoma. PATIENTS AND METHODS Between June 1992 and March 1994, 40 patients with metastatic malignant melanoma and no prior chemothe
Autor:
J. Jack Lee, Robert S. Benjamin, Charles M. Balch, S. S. Legha, Antonio C. Buzaid, Z N Tu, L A Tinoco, M. I. Ross, D Jendiroba
Publikováno v:
Journal of Clinical Oncology. 13:2361-2368
PURPOSE To determine the prognostic significance of the size of the lymph node mass as measured by physical examination (PE) and of the size of the largest node measured by pathologic analysis (path) in patients with cutaneous melanoma and nodal meta
Autor:
Alberto Fusi, Emilio Bajetta, Mario Roberto Sertoli, Barbara Formisano, Paola Taveggia, M. Del Vecchio, P. Nova, S. S. Legha, A. Daponte, Paola Queirolo, Natale Cascinelli, Maria Grazia Bernengo
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 17(4)
Background: The addition of cytokines to chemotherapy (CT) has obtained encouraging but contradictory results in metastatic melanoma. In this phase III trial, we compared the effects of CT [cisplatin, vindesine and dacarbazine (CVD)] with those of co