Zobrazeno 1 - 10
of 12
pro vyhledávání: '"S S, Lakka"'
Autor:
S. S. Lakka, J. S. Rao
Publikováno v:
Matrix Metalloproteinases in the Central Nervous System
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e658b2406d9cca406afb657a3227a7ca
https://doi.org/10.1142/9781860947179_0011
https://doi.org/10.1142/9781860947179_0011
Autor:
S, Mohanam, S L, Jasti, S R, Kondraganti, N, Chandrasekar, Y, Kin, G N, Fuller, S S, Lakka, A P, Kyritsis, D H, Dinh, W C, Olivero, M, Gujrati, W K, Yung, J S, Rao
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(8)
The diffuse and extensive infiltration of malignant gliomas into the surrounding normal brain is believed to rely on modifications of the proteolysis of extracellular matrix components. A key molecule in regulating plasminogen-mediated extracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::801502bc23d955a15a96d35f07f1f9a4
https://pubmed.ncbi.nlm.nih.gov/11489835
https://pubmed.ncbi.nlm.nih.gov/11489835
Publikováno v:
Clinicalexperimental metastasis. 18(3)
Human tissue factor pathway inhibitor-2 (TFPI-2) is a Kunitz-type serine protease inhibitor that inhibits plasmin, trypsin, chymotrypsin, cathepsin G and plasma kallikrein but not urokinase (uPA) or tissue-type plasminogen activator and thrombin. Ear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fcf38c09b71218b5631d8a110154383a
https://pubmed.ncbi.nlm.nih.gov/11315097
https://pubmed.ncbi.nlm.nih.gov/11315097
Publikováno v:
Clinicalexperimental metastasis. 18(3)
Our previous studies have shown that MMP-9 levels are significantly elevated during the progression of human gliomas. In the current study, we examined the role of JNK- and ERK-dependent signaling modules in the regulation of MMP-9 production and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::209ce7e20af9e09c4ec0367dc39a4205
https://pubmed.ncbi.nlm.nih.gov/11315098
https://pubmed.ncbi.nlm.nih.gov/11315098
Autor:
S S, Lakka, R, Rajagopal, M K, Rajan, P M, Mohan, Y, Adachi, D H, Dinh, W C, Olivero, M, Gujrati, F, Ali-Osman, J A, Roth, W K, Yung, A P, Kyritsis, J S, Rao
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(4)
The urokinase-type plasminogen activator (uPA) and its receptor (uPAR) play an important role in the proteolytic cascade involved in the metastasis of lung and other cancers. We report that the reduction in uPAR levels produced by an antisense strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af1c0970714a92eb3518d800b8a62582
https://pubmed.ncbi.nlm.nih.gov/11309361
https://pubmed.ncbi.nlm.nih.gov/11309361
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(3)
Protease inhibitors regulate a variety of physiological and pathological processes including angiogenesis, embryo implantation, intravascular fibrinolysis, wound healing, and tumor invasion. Tissue factor pathway inhibitor (TFPI) 2 is a Mr 32,000 Kun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e2950ab7bc2a45f61ec8a6d45adf0c0
https://pubmed.ncbi.nlm.nih.gov/11297250
https://pubmed.ncbi.nlm.nih.gov/11297250
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(2)
We reported previously that the production of urokinase-type plasminogen activator receptor (uPAR) protein is greater in high-grade glioblastomas than in low-grade gliomas. Transcriptional activation of the uPAR gene or increased stability of the uPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51e0cf362a627931a397c06c3c4a2fb3
https://pubmed.ncbi.nlm.nih.gov/11234878
https://pubmed.ncbi.nlm.nih.gov/11234878
Autor:
S, Kondraganti, S, Mohanam, S K, Chintala, Y, Kin, S L, Jasti, C, Nirmala, S S, Lakka, Y, Adachi, A P, Kyritsis, F, Ali-Osman, R, Sawaya, G N, Fuller, J S, Rao
Publikováno v:
Cancer research. 60(24)
Increased expression of matrix metalloproteinases (MMPs) has been associated with human glioblastoma tumor progression. In this study, we sought to down-regulate MMP-9 expression by stably transfecting a high-grade glioblastoma cell line with a plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7222da8b0fefa6659f30c6ec4c379ac6
https://pubmed.ncbi.nlm.nih.gov/11156378
https://pubmed.ncbi.nlm.nih.gov/11156378
Publikováno v:
International journal of oncology. 18(1)
Urokinase-type plasminogen (uPA) activator regulates a variety of processes, including morphogenesis, cell differentiation, migration, and invasion. In previous studies, we demonstrated that uPA levels are significantly higher in anaplastic astrocyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27a44870b5d6c284720ebe5ca52215af
https://pubmed.ncbi.nlm.nih.gov/11115541
https://pubmed.ncbi.nlm.nih.gov/11115541
Autor:
P M, Mohan, S S, Lakka, S, Mohanam, Y, Kin, R, Sawaya, A P, Kyritsis, G L, Nicolson, J S, Rao
Publikováno v:
Clinicalexperimental metastasis. 17(7)
We previously showed that downregulation of the urokinase-type plasminogen activator receptor (uPAR) in the SNB19 human glioblastoma cell line by the stable transfection of a plasmid expressing a 300 bp antisense sequence to the 5' end of the uPAR ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a05e094ec100d3e5cc26cefd71801617
https://pubmed.ncbi.nlm.nih.gov/10845561
https://pubmed.ncbi.nlm.nih.gov/10845561