Zobrazeno 1 - 10
of 34
pro vyhledávání: '"S S, Kerwar"'
Autor:
James Joseph Gibbons, Susan Quinn Dejoy, Narendra R. Desai, Lawrence Wayne Torley, Walter C. Pickett, S. S. Kerwar, Arnold L. Oronsky
Publikováno v:
Critical Care Medicine. 20:1448-1453
Background and methods In murine models of endotoxemia, large amounts of lipopolysaccharide have to be administered to induce mortality. If mice are pretreated with D-galactosamine, the amount of lipopolysaccharide required to induce mortality is sig
Autor:
J B Hynes, T P McAlinden, G Jansen, G R Westerhof, S S Kerwar, James H. Freisheim, J H Schornagel, Shirish A. Patil
Publikováno v:
Biochemistry. 30:5674-5681
A fluorescein derivative of the lysine analogue of folic acid, N alpha-pteroyl-N epilson-(4'-fluoresceinthiocarbamoyl)-L-lysine (PLF), was synthesized as a probe for dihydrofolate reductase (DHFR) and a membrane folate binding protein (m-FBP). Excita
Publikováno v:
The Journal of Organic Chemistry. 59:6850-6852
Publikováno v:
Cancer research. 55(21)
Pulmonary vascular leak induced in mice by interleukin 2 (IL-2) was attenuated by pretreatment with single or multiple doses of oral methotrexate. Methotrexate also attenuated pulmonary vascular leak when either larger doses of IL-2 or when lymphokin
Autor:
Kenneth H. Grabstein, Robert Jeyaseelan, Michael M. Wick, Susan Quinn Dejoy, Lawrence Wayne Torley, June Eisenmann, William E. Munger, Ray Paxton, S. S. Kerwar, Tom Cox
Publikováno v:
Cellular immunology. 165(2)
Interleukin-15 is a new cytokine that stimulates the proliferation of T cells and other cells of the immune system. Some of the biological properties of interleukin-15 overlap that of interleukin-2. Using murine models, the present studies have shown
Publikováno v:
Agents and actions. 43(3-4)
Antiinflammatory and antiarthritic properties of a substituted quinoline carboxylic acid: CL 306,293
Autor:
A E, Sloboda, D, Powell, J F, Poletto, W C, Pickett, J J, Gibbons, D H, Bell, A L, Oronsky, S S, Kerwar
Publikováno v:
The Journal of rheumatology. 18(6)
CL 306,293, a substituted quinoline carboxylic acid at a daily oral dose between 1.5 and 3.0 mg/kg suppressed the inflammation and joint destruction (radiological criteria) associated with both developing and established adjuvant arthritis. When a we
Publikováno v:
Arthritis & Rheumatism. 27:1201-1209
Circulating antibodies to native and denatured types I and II human and bovine collagens were assayed in patients with rheumatoid arthritis (RA), patients with other rheumatic diseases, and normal individuals. A subgroup of this population was also a
Autor:
S. S. Kerwar, Adolph E. Sloboda
Publikováno v:
Agents and Actions. 12:216-220
The effects of fenbufen and sulindac, two novel antiinflammatory agents, on the developing and established lesion of type II collagen arthritis was investigated. Using paw diameter and radiology as parameters, these studies suggest that fenbufen is m
Autor:
Adolph E. Sloboda, S. S. Kerwar
Publikováno v:
Pharmacology. 25:12-20