Zobrazeno 1 - 10
of 202
pro vyhledávání: '"S S, Boggs"'
Publikováno v:
The Journal of Immunology. 157:2820-2829
For over 40 years, the association between hemopoietic chimerism and donor-specific tolerance for allografts has been recognized. However, toxicity associated with lethal conditioning has prevented the clinical application of bone marrow (BM) chimeri
Publikováno v:
The Journal of Immunology. 156:380-388
Evidence in experimental models suggests that many autoimmune diseases can be prevented by transplantation of bone marrow from disease-resistant donors. For potential clinical application, it would be important to avoid the morbidity and mortality as
Publikováno v:
The Journal of Immunology. 152:5171-5179
The role of the adhesion molecule CD44 in the development of NK cells was analyzed in a mouse long-term bone marrow culture system. After 4 wk of culture (day 0), recombinant human IL-2 was added and 13 days later the cells generated were shown to ha
Publikováno v:
Blood. 81:1489-1496
Mouse bone marrow (BM) was separated into low-density, lineage- negative, wheat germ agglutinin-positive (WGA+), Rhodamine-123 bright (Rhbright) or dim (Rhdim) cells to obtain populations that were highly enriched for committed progenitors (Rhbright
Autor:
Bryon E. Petersen, K. D. Patrene, Julie P. Goff, Wendy M. Mars, Joel S. Greenberger, W. C. Bowen, A. K. Sullivan, N. Murase, S. S. Boggs
Publikováno v:
Science. 284:1168-1170
Bone marrow stem cells develop into hematopoietic and mesenchymal lineages but have not been known to participate in production of hepatocytes, biliary cells, or oval cells during liver regeneration. Cross-sex or cross-strain bone marrow and whole li
Publikováno v:
Journal of neuro-oncology. 55(2)
Polyamine synthesis inhibitors, such as a-difluoromethylornithine (DFMO), inhibit tumor cell growth in vitro and in vivo. However, upon cessation of treatment, tumor growth resumes. We hypothesized that incorporation of radioactive polyamines might k
Publikováno v:
Journal of neuro-oncology. 42(2)
We have been exploring the feasibility of delivering ionizing radiation to brain tumor cells by using tritium labeled polyamines. Polyamines are taken up preferentially by dividing cells and form noncovalent bonds with DNA. Their uptake can be enhanc
Publikováno v:
Experimental hematology. 26(7)
Treatment of mouse bone marrow (BM) with rabbit anti-mouse brain serum (RAMBS) plus complement (C') depletes several cell types, including T cells and facilitating cells (FCs), that is, cells that facilitate engraftment of sorted allogeneic stem cell
Publikováno v:
Experimental hematology. 26(1)
The goal of the present work was to study the regulatory role of T lymphocytes on natural killer (NK) cell generation in NK long-term bone marrow cultures (LTBMCs), an established mouse long-term bone marrow (BM) culture system used for the study of
Publikováno v:
Radiation research. 147(1)
The role of recombinant hematopoietic growth factors in radiation repair has become a subject of increasing interest in both clinical and basic radiobiology. Combinations of cytokines such as hepatocyte growth factor, interleukin (IL)-3, IL-11, kit l