Supplementary material from Blocking Tumor-Educated MSC Paracrine Activity Halts Osteosarcoma Progression

Autor: D. Michiel Pegtel, Nicola Baldini, Tom Wurdinger, Sulev Köks, Katre Maasalu, Aare Martson, Vincenzo Canzonieri, Agostino Steffan, Silvia Cervo, Nicoletta Zini, Tanja D. de Gruijl, Sinead M. Lougheed, Roberta Bonafede, Massimo Dominici, Giulia Grisendi, Monique A.J. van Eijndhoven, Michelina Greco, Laura Roncuzzi, Ekaterina S. Jordanova, Anne-Marie Cleton-Jansen, Sonia A. Melo, Nicolas Léveillé, Xuan Dung Ho, Maria Pérez-Lanzón, Tonny Lagerweij, S. Rubina Baglio

Supplementary figures and legends and supplementary tables

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f2021d751dee43905d9f797bc462c3
https://doi.org/10.1158/1078-0432.22466991.v1

Extracellular Vesicle-Based Nucleic Acid Delivery: Current Advances and Future Perspectives in Cancer Therapeutic Strategies

Autor: Crescenzo Massaro, Giulia Sgueglia, Victoria Frattolillo, S. Rubina Baglio, Lucia Altucci, Carmela Dell'Aversana

Publikováno v: Pharmaceutics, Vol 12, Iss 10, p 980 (2020)

Extracellular vesicles (EVs) are sophisticated and sensitive messengers released by cells to communicate with and influence distant and neighboring cells via selective transfer of bioactive content, including protein lipids and nucleic acids. EVs hav

Externí odkaz: https://doaj.org/article/86a5282251db4d7bac3c32082de85c5c

Censoring exosomal crosstalk in osteoarthritis

Autor: Ingrid Meulenbelt, S. Rubina Baglio, D. Michiel Pegtel, Yolande F M Ramos

Publikováno v: Nature Aging, 1(4), 332-334. Springer
Meulenbelt, I, Ramos, Y F M, Baglio, S R & Pegtel, D M 2021, ' Censoring exosomal crosstalk in osteoarthritis ', Nature Aging, vol. 1, no. 4, pp. 332-334 . https://doi.org/10.1038/s43587-021-00052-4

Using mouse models of osteoarthritis (OA), a new study finds that osteoclasts secrete exosomes that deliver miRNAs to chondrocytes, leading to an increase in metalloproteinase activity in cartilage. A bone-specific inhibitor of exosome production can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c01df3aee2faed74bb4cce41e594135
https://research.vumc.nl/en/publications/466eac18-f77b-4515-8fd6-583ad44748ac

Packaging RNA drugs into extracellular vesicles

Autor: Monique A J, van Eijndhoven, S Rubina, Baglio, D Michiel, Pegtel

Publikováno v: Nature biomedical engineering. 4(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::397464a4a9f8709e83faa91ebbdc3f14
https://pubmed.ncbi.nlm.nih.gov/31937944

Biogenesis and function of extracellular vesicles in cancer

Autor: S. Rubina Baglio, Martine J. Smit, D. Michiel Pegtel, Maarten P. Bebelman

Publikováno v: Bebelman, M P, Smit, M J, Pegtel, D M & Baglio, S R 2018, ' Biogenesis and function of extracellular vesicles in cancer ', Pharmacology and Therapeutics, vol. 188, pp. 1-11 . https://doi.org/10.1016/j.pharmthera.2018.02.013
Bebelman, M P, Smit, M J, Pegtel, D M & Baglio, S R 2018, ' Biogenesis and function of extracellular vesicles in cancer ', Pharmacology and Therapeutics, vol. 188, pp. 1-11 . https://doi.org/10.1016/j.pharmthera.2018.02.013, https://doi.org/10.1016/j.pharmthera.2018.02.013
Pharmacology & Therapeutics

Extracellular vesicles (EVs) are heterogeneous multi-signal messengers that support cancer growth and dissemination by mediating the tumor-stroma crosstalk. Exosomes are a subtype of EVs that originate from the limiting membrane of late endosomes, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58c517abb5910b5fe9973dca28e9f00
https://hdl.handle.net/1871.1/2ae8e649-8282-4c7c-87fb-fbb0c1887584