Zobrazeno 1 - 10
of 18
pro vyhledávání: '"S R Sarawar"'
Publikováno v:
The Journal of Experimental Medicine
A unique experimental model has been developed for dissecting the integrity of CD8+ T cell-mediated immunity to a persistent gammaherpesvirus under conditions of CD4+ T cell deficiency. Respiratory challenge of major histocompatibility complex class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a031d25f9a599474b02ee3c4a3d8ad
http://europepmc.org/articles/PMC2192775
http://europepmc.org/articles/PMC2192775
Publikováno v:
Scopus-Elsevier
The possible involvement of cytokines in the acute viral pneumonia induced by the murine parainfluenza type 1 virus, Sendai virus, was studied. Cytokine profiles for both the respiratory tract and the draining mediastinal lymph node (MLN) of virus-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64cb1288ac69bd185fbcd1c6658fc12
https://doi.org/10.1128/jvi.69.2.1288-1291.1995
https://doi.org/10.1128/jvi.69.2.1288-1291.1995
Publikováno v:
Scopus-Elsevier
Subclinical lymphocytic choriomeningitis virus infection primes mice expressing a V beta 8.1D beta 2J beta 2.3C beta 2 T cell receptor as a transgene for induction of fatal hematogenous shock after administration of a dose of staphylococcal enterotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb02af9b835eedf23a49469cd68d6be0
https://doi.org/10.1093/infdis/170.5.1189
https://doi.org/10.1093/infdis/170.5.1189
Publikováno v:
The Journal of Immunology. 153:1246-1253
Treatment of mice that were homozygous for a beta 2-microglobulin gene disruption with a mAb that was specific for IFN-gamma delayed clearance of an influenza A virus from the respiratory tract for at least 3 days, whereas administration of an anti-I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e96b656c062937af88722be792aef911
https://doi.org/10.4049/jimmunol.153.3.1246
https://doi.org/10.4049/jimmunol.153.3.1246
Publikováno v:
Virology. 249(2)
Murine gammaherpesvirus-68 (MHV-68) induces high levels of interleukin (IL)-6 production in both naive and primed lymphocyte populations. Mice that are homozygous (−/−) for deletion of the IL-6 gene were used to investigate the role of this cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11819616b3b3999cddb914aa3109ff8d
https://pubmed.ncbi.nlm.nih.gov/9791027
https://pubmed.ncbi.nlm.nih.gov/9791027
Autor:
James W. Brooks, William D. Young, S R Sarawar, Deborah J. Allen, Rhonda D. Cardin, Edward J. Usherwood, Peter C. Doherty, Anthony Nash
Publikováno v:
The Journal of general virology. 78
Perforin-mediated cytotoxic T cell killing has been suggested to be of importance in the control of noncytopathic virus infections, based on studies with lymphocytic choriomeningitis virus (LCMV). We examined the role of perforin in a mouse model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f6f25ff3e99f3dc30aa81ed3c21eb1
https://pubmed.ncbi.nlm.nih.gov/9267003
https://pubmed.ncbi.nlm.nih.gov/9267003
Autor:
Peter C. Doherty, Mehdi Mehrpooya, James W. Brooks, Xia Yan Mo, S R Sarawar, Rhonda D. Cardin, Ann Marie Hamilton-Easton
Publikováno v:
Journal of virology. 71(5)
Murine gammaherpesvirus 68 (MHV-68) when administered intranasally induces high levels of gamma interferon (IFN-gamma) in the lymphoid tissues of infected mice. In order to investigate the role of this cytokine in the immune response to MHV-68, mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fac19539b893c52e49e3681207017d3
https://pubmed.ncbi.nlm.nih.gov/9094668
https://pubmed.ncbi.nlm.nih.gov/9094668
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(7)
The role of B lymphocytes and their Ig product in the development and maintenance of virus-specific CD4+ T cells has been analyzed in mice homozygous for disruption of the Ig mu gene (mu MT). These mice lack mature B220+ B cells and do not secrete Ig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2fe520cec825782e1ab900c0d9ac5e6
https://pubmed.ncbi.nlm.nih.gov/8816401
https://pubmed.ncbi.nlm.nih.gov/8816401
Autor:
Dario A. A. Vignali, Mark Y. Sangster, J. M. Van Deursen, William E. Thierfelder, S. R. Sarawar, R. T. Carson, Peter C. Doherty, G. C. Grosveld, K. Yamamoto, James N. Ihle, Ralph A. Tripp
Publikováno v:
Nature. 382(6587)
Signal transducers and activators of transcription (STATs) are activated by tyrosine phosphorylation in response to cytokines and mediate many of their functional responses. Stat4 was initially cloned as a result of its homology with Stat1 (refs 4, 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb55aac1307a68266d003c9c237df3d6
https://pubmed.ncbi.nlm.nih.gov/8700208
https://pubmed.ncbi.nlm.nih.gov/8700208
Autor:
Rhonda D. Cardin, James W. Brooks, S R Sarawar, Peter C. Doherty, Mehdi Mehrpooya, Ralph A. Tripp
Cytokine profiles were determined following intranasal infection of C57BL/6J mice with murine gammaherpesvirus 68 (MHV-68). Spleen, mediastinal, and cervical lymph node cells from infected mice produced high levels of interleukin 6 (IL-6) and gamma i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200303824a836e54951c1f7ac8693278
https://europepmc.org/articles/PMC190192/
https://europepmc.org/articles/PMC190192/
