Zobrazeno 1 - 10
of 23
pro vyhledávání: '"S R Riddell"'
Autor:
S. Fiorenza, Y. Zheng, J. Purushe, T. J. Bock, J. Sarthy, D. H. Janssens, A. S. Sheih, E. L. Kimble, D. Kirchmeier, T. D. Phi, J. Gauthier, A. V. Hirayama, S. R. Riddell, Q. Wu, R. Gottardo, D. G. Maloney, J. Y. H. Yang, S. Henikoff, C. J. Turtle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Chimeric antigen receptor-modified T cell (CAR-T) immunotherapy has revolutionised blood cancer treatment. Parsing the genetic underpinnings of T cell quality and CAR-T efficacy is challenging. Transcriptomics inform CAR-T state, but the nat
Externí odkaz:
https://doaj.org/article/99952e45b80a494cbf0a1c52b7763252
Publikováno v:
The Journal of Immunology. 157:4079-4086
The identification of Ags expressed by tumor cells and recognized by autologous T cells has led to the prospect of treating cancer by adoptive transfer of tumor-reactive T cells selected for Ag specificity. Tyrosinase is an Ag expressed by normal mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c289776bf54ea19917fa08f17c5ab4c9
https://doi.org/10.4049/jimmunol.157.9.4079
https://doi.org/10.4049/jimmunol.157.9.4079
Publikováno v:
Blood. 83:1971-1979
Protection from cytomegalovirus (CMV) disease in immunocompromised hosts has been shown to correlate with recovery of the host virus- specific CD8+ T-cell response. The administration of ganciclovir to immunosuppressed transplant recipients as antivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4efdc0af1de63371dcda422591b9d2
https://doi.org/10.1182/blood.v83.7.1971.bloodjournal8371971
https://doi.org/10.1182/blood.v83.7.1971.bloodjournal8371971
Autor:
S R Riddell, Ulrike Protzer
Chimeric antigen receptors (CARs) are major histocompatibility complex (MHC)-independent one-polypeptide chain receptor molecules that, when expressed in T cells, can redirect specificity towards tumor or viral antigens. The antigen-binding domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99317f01e03be822b8f0129c84d68ec1
https://europepmc.org/articles/PMC6953742/
https://europepmc.org/articles/PMC6953742/
Publikováno v:
The Journal of Immunology. 146:4414-4420
The therapeutic efficacy of adoptive immunotherapy of cancer has been shown to positively correlate with the dose of tumor-immune T cells transferred. Therefore, the success of this therapy is critically dependent on the ability to procure large numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45332b26ea672e0a61d14a9be07d2b7b
https://doi.org/10.4049/jimmunol.146.12.4414
https://doi.org/10.4049/jimmunol.146.12.4414
Publikováno v:
The Journal of Immunology. 146:2795-2804
The human pathogen CMV, is a major cause of morbidity and mortality in immunocompromised hosts. The CD8+ class I-restricted CTL response to CMV assists in preventing progression of CMV infection to life-threatening disease; however, the viral Ag reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6c8fe97ef16313e146af9b75fa31f65
https://doi.org/10.4049/jimmunol.146.8.2795
https://doi.org/10.4049/jimmunol.146.8.2795
Autor:
E H, Warren, B E, Otterud, R W, Linterman, A G, Brickner, V H, Engelhard, M F, Leppert, P J, Martin, S R, Riddell
Publikováno v:
Tissue antigens. 59(4)
We have evaluated the utility of genetic linkage analysis to identify genes that encode minor histocompatibility antigens using vaccinia virus vectors as a simple and convenient method for transient expression of class I MHC molecules in lymphoblasto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::70712eff795f052a8e7b2e7b85c4fd4f
https://pubmed.ncbi.nlm.nih.gov/12135428
https://pubmed.ncbi.nlm.nih.gov/12135428
Autor:
C, Yee, J A, Thompson, P, Roche, D R, Byrd, P P, Lee, M, Piepkorn, K, Kenyon, M M, Davis, S R, Riddell, P D, Greenberg
Publikováno v:
The Journal of Experimental Medicine
Current strategies for the immunotherapy of melanoma include augmentation of the immune response to tumor antigens represented by melanosomal proteins such as tyrosinase, gp100, and MART-1. The possibility that intentional targeting of tumor antigens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::888b6572a70c9747f8cbd0f46cca52e0
https://pubmed.ncbi.nlm.nih.gov/11104805
https://pubmed.ncbi.nlm.nih.gov/11104805
Autor:
S. R. Riddell, P. D. Greenberg
Publikováno v:
The Journal of antimicrobial chemotherapy. 45
Acute and persistent virus infections are limited by the development and maintenance of host T-cell responses to viral antigens. Individuals with congenital or acquired immunodeficiencies are at risk of progressive and often life-threatening infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac5c14eb1d5603442f2b471f8cabc09
https://pubmed.ncbi.nlm.nih.gov/10855770
https://pubmed.ncbi.nlm.nih.gov/10855770
Autor:
S A, Rosenberg, R M, Blaese, M K, Brenner, A B, Deisseroth, F D, Ledley, M T, Lotze, J M, Wilson, G J, Nabel, K, Cornetta, J S, Economou, S M, Freeman, S R, Riddell, M, Brenner, E, Oldfield, B, Gansbacher, C, Dunbar, R E, Walker, F G, Schuening, J A, Roth, R G, Crystal, M J, Welsh, K, Culver, H E, Heslop, J, Simons, R W, Wilmott, R C, Boucher, H F, Siegler, J A, Barranger, S, Karlsson, D, Kohn, J E, Galpin, C, Raffel, C, Hesdorffer, J, Ilan, P, Cassileth, J, O'Shaughnessy, L E, Kun, T K, Das, F, Wong-Staal, R E, Sobol, R, Haubrich, M, Sznol, J, Rubin, E J, Sorcher, J, Rosenblatt, R, Walker, K, Brigham, N, Vogelzang, E, Hersh, S L, Eck
Publikováno v:
Human gene therapy. 11(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::583bce52afebbe5f92308012337fda38
https://pubmed.ncbi.nlm.nih.gov/10779168
https://pubmed.ncbi.nlm.nih.gov/10779168