Zobrazeno 1 - 10
of 18
pro vyhledávání: '"S R Panini"'
Publikováno v:
Journal of Lipid Research, Vol 27, Iss 11, Pp 1190-1204 (1990)
Treatment of rat intestinal epithelial cell cultures with the oxidosqualene cyclase inhibitor, 3 beta-[2-(diethylamino)-ethoxy]androst-5-en-17-one (U18666A), resulted in an accumulation of squalene 2,3:22,23-dioxide (SDO). When U18666A was withdrawn
Externí odkaz:
https://doaj.org/article/96c1c06bc0e34a83bb5bc8fa59f2b3ba
Publikováno v:
Journal of Lipid Research, Vol 20, Iss 7, Pp 879-889 (1979)
3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase, E.C. 1.1.1.34), the major rate-limiting enzyme of the sterol biosynthetic pathway, was studied in ileal epithelial cells isolated in a villus-to-crypt gradient according to Weiser (W
Externí odkaz:
https://doaj.org/article/e27d33cd351c47cbb98bd5502b0c9bf7
Publikováno v:
Journal of Biological Chemistry. 267:12647-12654
We have examined the mechanism of regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 24(S),25-oxidolanosterol, a C30-sterol naturally occurring in mammalian tissues. In the absence of enzymatic demethylation to the C27-sterol, 24(S),25-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b5818fd5e7f277f957b83eaa15daa30
https://doi.org/10.1016/s0021-9258(18)42326-5
https://doi.org/10.1016/s0021-9258(18)42326-5
Publikováno v:
Journal of lipid research. 42(10)
Owing at least in part to oxysterol components that can induce apoptosis, oxidized LDL (oxLDL) is cytotoxic to mammalian cells with receptors that can internalize it. Vascular cells possess such receptors, and it appears that the apoptotic response o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40a5ba42ba22c965fa7bbb7425c63ccd
https://pubmed.ncbi.nlm.nih.gov/11590225
https://pubmed.ncbi.nlm.nih.gov/11590225
Publikováno v:
The Journal of biological chemistry. 267(27)
Numerous studies have indicated that cytoplasmic intermediate filaments (cIFs) can associate with cellular lipids. To determine if these interactions might have functional consequences, we have studied the lipid metabolism of human SW-13 adrenal tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c94baab3e459ca0909ebf7042bb00207
https://pubmed.ncbi.nlm.nih.gov/1527066
https://pubmed.ncbi.nlm.nih.gov/1527066
Autor:
S R, Panini, R J, Lutz, L, Wenger, J, Miyake, S, Leonard, A, Andalibi, A J, Lusis, M, Sinensky
Publikováno v:
The Journal of biological chemistry. 265(24)
The Chinese hamster ovary recessive mutant, crB, has been selected for its resistance to the cytotoxic effects of 25-hydroxycholesterol in sterol-free media (Sinensky, M., Logel, J., and Torget, R. (1982) J. Cell. Physiol. 113, 314-319). Growth of cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df31170528d5f67ced3c1056b57b5755
https://pubmed.ncbi.nlm.nih.gov/2117604
https://pubmed.ncbi.nlm.nih.gov/2117604
Autor:
H Rudney, S R Panini
Publikováno v:
Journal of Biological Chemistry. 255:11633-11636
In ileal epithelial cells isolated through incubation of gut loops in phosphate-buffered saline containing EDTA, 3-hydroxy-3-methylglutaryl coenzyme A reductase was found to exist prdominantly in an active (dephosphorylated) form. However, in cells o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d23179d0a775e44423d062b5f2016d89
https://doi.org/10.1016/s0021-9258(19)70175-6
https://doi.org/10.1016/s0021-9258(19)70175-6
Publikováno v:
Journal of Biological Chemistry. 264:11044-11052
In this paper, we assess the relative degree of regulation of the rate-limiting enzyme of isoprenoid biosynthesis, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, by sterol and nonsterol products of mevalonate by utilizing cultured Chinese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9bda8c27ca9cd07b889407be6a57031
https://doi.org/10.1016/s0021-9258(18)60424-7
https://doi.org/10.1016/s0021-9258(18)60424-7
Autor:
S. R. Panini, C. K. Ramakrishna Kurup
Publikováno v:
Biochemical Journal. 142:253-261
1. α-p-Chlorophenoxyisobutyric acid, the ethyl ester of which is widely used as an antihypercholesterolaemic drug, is an inhibitor of energy-transfer reactions in isolated rat liver mitochondria. 2. The compound at lower concentrations (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa03703446d52408db4649da465bed4
https://doi.org/10.1042/bj1420253
https://doi.org/10.1042/bj1420253
Autor:
S. R. Panini, C. K. Ramakrishna Kurup
Publikováno v:
Archives of Biochemistry and Biophysics. 168:188-197
The antihypercholesterolemic drug clofibrate (ethyl-α-p-chlorophenoxyisobutyrate) stimulated the latent ATPase activity and “superstimulated” the uncoupler-induced ATPase activity of rat-liver mitochondria. Addition of clofibrate decreased the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e0cb6329779657500434e9a495cf13
https://doi.org/10.1016/0003-9861(75)90241-6
https://doi.org/10.1016/0003-9861(75)90241-6