Zobrazeno 1 - 10
of 22
pro vyhledávání: '"S R Keyes"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(2)
In the design of sequential high-dose chemotherapy regimens, the selection of antitumor alkylating agents to be included in each intensification and the interval between the intensifications are critical to the design of the therapy. The tumor cell s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5f57e12dc9b74aa32b86cd705c6f793
https://pubmed.ncbi.nlm.nih.gov/9516940
https://pubmed.ncbi.nlm.nih.gov/9516940
Publikováno v:
In vivo (Athens, Greece). 11(6)
The gene for transforming growth factor-beta 1 (TGF-beta 1) was transfected into the murine EMT-6/Parent mammary carcinoma tumor line to form the EMT6/PRK5 beta 1E tumor line. In monolayer culture the EMT-6/PRK5 beta 1E tumor line secretes about 15-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e039c1c59a9866b69a47351bfea6ea79
https://pubmed.ncbi.nlm.nih.gov/9509296
https://pubmed.ncbi.nlm.nih.gov/9509296
Publikováno v:
International journal of cancer. 71(1)
Transforming growth factor-beta (TGF-beta) has been implicated in the in vivo resistance of the EMT-6/CTX and EMT-6/ CDDP murine mammary tumors. Both of these tumors have a higher number of intratumoral vessels than the EMT-6/ parent tumor. Animals b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b5dc7c11667e49ce39e98ccb5ad1cc6
https://pubmed.ncbi.nlm.nih.gov/9096665
https://pubmed.ncbi.nlm.nih.gov/9096665
Publikováno v:
Oncology research. 8(12)
Lisofylline is a new methylxanthine. The potential of lisofylline to enhance the response to ionizing radiation of the EMT-6 murine mammary carcinoma in vitro and in vivo was assessed and compared with pentoxifylline. Addition of lisofylline (100 mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e85bf42501305d252f137e72f08520e
https://pubmed.ncbi.nlm.nih.gov/9160355
https://pubmed.ncbi.nlm.nih.gov/9160355
Publikováno v:
The Journal of Cell Biology
Further evidence for organelle interaction during drug metabolism by the liver is presented. The apparent stimulation by succinate of formaldehyde accumulation in the medium, which was reported to occur with liver slices and homogenates as well as wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0162805a27528942a9e9a5d3118ef87
http://europepmc.org/articles/PMC2109712
http://europepmc.org/articles/PMC2109712
Autor:
S R Keyes, Gary Rudnick
Publikováno v:
Journal of Biological Chemistry. 257:1172-1176
A pH difference (acid inside) across the platelet plasma membrane increases both the rate and extent of serotonin accumulation inside plasma membrane vesicles. Even in the absence of other transmembrane ion gradients, this pH difference (delta pH) se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cc5b537f229001b0f32258ce9c01b61
https://doi.org/10.1016/s0021-9258(19)68170-6
https://doi.org/10.1016/s0021-9258(19)68170-6
Publikováno v:
Journal of Biological Chemistry. 251:1571-1577
The oxidation of formaldehyde by rat liver mitochondria in the presence of 50 mM phosphate was enhanced 2-fold by exogenous NAD+. Absolute requirement of NAD+ for formaldehyde oxidation was demonstrated by depleting the mitochondria of their NAD+ con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7599b9cf829ebae1d62778e538b9a494
https://doi.org/10.1016/s0021-9258(17)33686-4
https://doi.org/10.1016/s0021-9258(17)33686-4
Publikováno v:
Journal of Biological Chemistry. 255:11357-11364
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b48cba3fe5fb13ea8ed361cdca16958
https://doi.org/10.1016/s0021-9258(19)70300-7
https://doi.org/10.1016/s0021-9258(19)70300-7
Publikováno v:
Cancer research. 48(19)
Aerobic and hypoxic cultures of EMT6 mouse mammary tumor cells were used to study the effects of dicoumarol (DIC) on the cytotoxicity of mitomycin C (MC). DIC protected aerobic cells from MC toxicity, but sensitized hypoxic cells to the cytotoxic act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00d66a46141c431177767268ca16c737
https://pubmed.ncbi.nlm.nih.gov/2458178
https://pubmed.ncbi.nlm.nih.gov/2458178
Publikováno v:
Cancer research. 49(12)
We have demonstrated previously that dicoumarol (DIC) increased the generation of reactive metabolites from mitomycin C (MC) in EMT6 cells under hypoxic conditions in vitro. This increased reaction rate was associated with an increased toxicity of MC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3b8f17c2362e2e446f127829c26f37c
https://pubmed.ncbi.nlm.nih.gov/2470504
https://pubmed.ncbi.nlm.nih.gov/2470504