Zobrazeno 1 - 10
of 21
pro vyhledávání: '"S R D Johnston"'
Autor:
Ben P. Haynes, G. W. Halbert, M. Brampton, B. Nutley, P. Canney, T. J. Powles, L. A. Gumbrell, J. Haviland, T. R. J. Evans, M. Soukop, Helena M. Earl, Mitch Dowsett, Anthony Howell, D. W. Rea, M. Jarman, I. E. Smith, Roger Grimshaw, R. C. Coombes, S. R. D. Johnston, C. J. Twelves, Robert E. Coleman, A. Jones
Publikováno v:
Cancer Chemotherapy and Pharmacology. 53:341-348
Idoxifene is a novel selective oestrogen receptor modulator (SERM) which had greater binding affinity for the oestrogen receptor (ER) and reduced agonist activity compared with tamoxifen in preclinical studies. In a randomized phase II trial in 56 po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732c071ca26af2308c155a94950de380
https://doi.org/10.1007/s00280-003-0733-6
https://doi.org/10.1007/s00280-003-0733-6
Publikováno v:
Annals of Oncology. 14:1629-1633
Third-generation aromatase inhibitors are being considered as an alternative to tamoxifen as first-line therapy for advanced breast cancer. These newer therapies are more expensive, and will gain greater acceptance if they can demonstrate cost-effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b89c55333d2034feb5b89479ac086c
https://doi.org/10.1093/annonc/mdg447
https://doi.org/10.1093/annonc/mdg447
Autor:
Robert C. Rees, J. D. Harris, S. R. D. Johnston, J. M. Thomas, Sheila Rodgers, K. J. Palmer, AK Murray, J. Moore, John M. Kirkwood, P. G. Riches, R. Mascari, Cyril Fisher, M. Everard, Martin Gore, Mark Harries, Mary Collins
Publikováno v:
Human Gene Therapy. 10:1261-1268
We vaccinated metastatic melanoma patients with irradiated, autologous melanoma cells genetically engineered to secrete interleukin 2 (IL-2) to investigate whether an anti-tumor immune response would be induced. Melanoma cell cultures were establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af555a3171f1b925dc39f3e1c35d6f20
https://doi.org/10.1089/10430349950017941
https://doi.org/10.1089/10430349950017941
Publikováno v:
Journal of Clinical Pathology. 47:900-905
AIM--To validate the use of a new mouse monoclonal antibody (1D5) directed against the N-terminal domain (A/B region) of the oestrogen receptor in an immunohistochemical assay (ER-IHA) for paraffin wax embedded tissue. METHODS--Breast cancer specimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06ebc00c462a9d64cd25a398e39cef1
https://doi.org/10.1136/jcp.47.10.900
https://doi.org/10.1136/jcp.47.10.900
Autor:
S R D, Johnston
Publikováno v:
European journal of cancer care. 19(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff99daefaabfca5b9e8c0edac18fdfee
https://pubmed.ncbi.nlm.nih.gov/20735466
https://pubmed.ncbi.nlm.nih.gov/20735466
Publikováno v:
Annals of Oncology. 3:503-511
Breast cancer patients who acquire tamoxifen resistance may respond to second-line hormonal therapy or progress to true endocrine resistance. The biological basis for these processes are poorly understood. Following successful therapy with tamoxifen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58329bf4af187966d4a47eb37eeafe4
https://doi.org/10.1093/oxfordjournals.annonc.a058251
https://doi.org/10.1093/oxfordjournals.annonc.a058251
Publikováno v:
Journal of Infection. 24:185-189
The clinical course of cryptococcal meningitis in AIDS shows some important differences from the features of the illness in non-AIDS patients. Complications such as raised intracranial pressure and visual impairment that are recognised in non-AIDS pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a301015e6340182db8dec791f63f88e
https://doi.org/10.1016/0163-4453(92)92954-h
https://doi.org/10.1016/0163-4453(92)92954-h
Autor:
S. R. D. Johnston
Publikováno v:
Breast Cancer Online. 10
Therapies that target cancers according to their characteristics (estrogen receptor +ve or –ve, for example) have been a major development in treating cancers successfully and have led to an increase in survival rates. These successes have led to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdf341b1f7d68dd628148033aad48fcc
https://doi.org/10.1017/s1470903107006086
https://doi.org/10.1017/s1470903107006086
Publikováno v:
Thorax. 47:660-662
A large mediastinal bronchogenic cyst presented acutely with paroxysmal atrial fibrillation and severe airflow obstruction. The patient had experienced identical symptoms on two other occasions over the previous 24 years. These had been previously mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54259d69c67a268a40e8f4b96caacd3a
https://doi.org/10.1136/thx.47.8.660
https://doi.org/10.1136/thx.47.8.660