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Gastric antisecretory and pharmacologic properties of N,N-dimethyl-N'-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyridyl)ur ea (L-634,366)

Autor: M L, Torchiana, P G, Cook, C A, Hanson, C A, Wesley, B L, Westrick, S R, Wiese, E A, Risley, M, Williams

Publikováno v: Archives internationales de pharmacodynamie et de therapie. 281(1)

N,N-Dimethyl-N'-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyridyl)urea (L-634,366) was selected from a series of pyridylurea compounds with antisecretory activity as a potential therapeutic agent for the treatment of ulcer disease. L-634,366 was an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d7d25d358ddb74e77e666944cad544b
https://pubmed.ncbi.nlm.nih.gov/2875693

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Subcutaneous administration of somatostatin analogs as a major factor in the enhancement of the duration of action

Autor: M L, Torchiana, P G, Cook, S R, Wiese, R, Saperstein, D F, Veber

Publikováno v: Archives internationales de pharmacodynamie et de therapie. 235(1)

Somatostatin and Des(Ala1Gly2)desaminol[Cys3]descarboxy-]Cys14[-]D-Trp8[dicarba3,14-somatostatin (Ia) are more potent inhibitors of glucagon, insulin and growth hormone release than the L-Trp8 analog (Ib). However when infused intravenously, these th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::04d460176750214a2b05427a9ac2d64c
https://pubmed.ncbi.nlm.nih.gov/736688

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