Výsledky vyhledávání - "S R, Schlemmer"

Endometrial stromal cells regulate gap-junction function in normal human endometrial epithelial cells but not in endometrial carcinoma cells

Autor: S R, Schlemmer, D G, Kaufman

Publikováno v: Molecular carcinogenesis. 28(2)

Gap junctions are transmembrane proteins comprised of six connexin subunits that facilitate direct solute transport between adjacent cells through gap junctions. Previous studies from other laboratories have documented a correlation between reduced g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a5bf7199a00b9f58472625227dbae3e
https://pubmed.ncbi.nlm.nih.gov/10900463

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Functional studies of P-glycoprotein in inside-out plasma membrane vesicles derived from murine erythroleukemia cells overexpressing MDR 3. Properties and kinetics of the interaction of vinblastine with P-glycoprotein and evidence for its active mediated transport

Autor: S R, Schlemmer, F M, Sirotnak

Publikováno v: The Journal of biological chemistry. 269(49)

Active [3H]vinblastine (VBL) transport (efflux) was documented for inside-out plasma membrane vesicles from murine erythroleukemia cells (MEL/VCR-6) resistant to vinca alkaloids and overexpressing MDR 3 P-glycoprotein (P-gp) 80-fold. Uptake of [3H]VB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::56bda0b4a0b97a0b9763d28cf7659ba7
https://pubmed.ncbi.nlm.nih.gov/7983045

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Retentiveness of methotrexate polyglutamates in cultured L1210 cells. Evidence against a role for mediated plasma membrane transport outward

Autor: S R, Schlemmer, F M, Sirotnak

Publikováno v: Biochemical pharmacology. 45(6)

In the present report, studies are described examining the issue of methotrexate (MTX) polyglutamate retentiveness in cultured L1210 cells. Measurements made in intact L1210 cells showed that the rate of egress of [3H]MTX and [3H]MTX+G1 was different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::413a58d1444c81259670503217dbead8
https://pubmed.ncbi.nlm.nih.gov/7682074

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Energy-dependent efflux of methotrexate in L1210 leukemia cells. Evidence for the role of an ATPase obtained with inside-out plasma membrane vesicles

Autor: S R, Schlemmer, F M, Sirotnak

Publikováno v: The Journal of biological chemistry. 267(21)

Earlier studies from our laboratory (Dembo, M., Sirotnak F. M., and Moccio, D. M. (1984) J. Membr. Biol. 78, 9-17) suggested that methotrexate (MTX) efflux from L1210 cells was mediated predominantly by an ATP-dependent, outwardly directed, mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bf14f86414c87a72e3b2447f0b150de
https://pubmed.ncbi.nlm.nih.gov/1386081

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