Zobrazeno 1 - 9
of 9
pro vyhledávání: '"S R, Sahasrabudhe"'
Publikováno v:
Genetics. 129:981-989
As the most nucleophilic site in DNA, the guanine N7 atom is a major site of adduction by a large number of alkylating mutagens and carcinogens. Aflatoxin B(1), a powerful mutagen, is believed to act through its reaction with this DNA site. On the ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d198cd866bdc3d0544562fa633679e
https://doi.org/10.1093/genetics/129.4.981
https://doi.org/10.1093/genetics/129.4.981
Autor:
J S, Jacobsen, M A, Spruyt, A M, Brown, S R, Sahasrabudhe, A J, Blume, M P, Vitek, H A, Muenkel, J, Sonnenberg-Reines
Publikováno v:
The Journal of biological chemistry. 269(11)
Amyloid precursor protein (APP) is cleaved predominantly within the beta amyloid peptide (BAP) domain to release a non-amyloidogenic amino-terminal PN2 fragment. Treatment of cells with phorbol dibutyrate, an agent which activates protein kinase C, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f76b8a2898899f160abbfb3730a70576
https://pubmed.ncbi.nlm.nih.gov/8132561
https://pubmed.ncbi.nlm.nih.gov/8132561
Autor:
S R, Sahasrabudhe, A M, Brown, J D, Hulmes, J S, Jacobsen, M P, Vitek, A J, Blume, J L, Sonnenberg
Publikováno v:
The Journal of biological chemistry. 268(22)
The major pathological change in Alzheimer's disease is the deposition of 39-42-amino acid beta-amyloid peptide (BAP) in the brain. Since BAP begins at the aspartate residue (Asp1, or codon 672 of the amyloid precursor protein (APP)770 transcript), t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8aad8eba2a4fd43461710ccad6b7343d
https://pubmed.ncbi.nlm.nih.gov/8344949
https://pubmed.ncbi.nlm.nih.gov/8344949
Publikováno v:
The Journal of biological chemistry. 267(35)
Abnormal proteolytic processing of amyloid precursor protein (APP) is thought to be central to the formation and deposition of beta amyloid peptide in Alzheimer's disease. A putative "secretase" activity normally releases an amino-terminal APP fragme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eecfdb46a95e0628db5dbaf605067d04
https://pubmed.ncbi.nlm.nih.gov/1281162
https://pubmed.ncbi.nlm.nih.gov/1281162
Autor:
S. R. Sahasrabudhe, R. Becklin, T. Erkkila, Paul B. Robbins, A. Senina, R. Venkat, S. K. Richards, C. Clemens, M. Rebentisch, M. Pierce, S. Lai
Publikováno v:
Journal of Clinical Oncology. 26:14586-14586
14586 Background: PRLX 93936 is a novel small molecule exhibiting therapeutic potential in an array of in vitro and in vivo tumor models many with limited treatment options such as melanoma. Developed and characterized in cell-based phenotypic assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65e90e3e7d557ba491a067ccc6b9d755
https://doi.org/10.1200/jco.2008.26.15_suppl.14586
https://doi.org/10.1200/jco.2008.26.15_suppl.14586
Publikováno v:
Applied Microbiology and Biotechnology. 21
Aspergillus niger and Aspergillus japonicus mycelia immobilized in calcium alginate could transform aromatic hydrocarbons at rates comparable to those of free mycelia. Conditions for the dehalogenation of chlorobenzoates by immobilized A. niger mycel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c76b6a06bffa63211ef1e2851d6fe33a
https://doi.org/10.1007/bf00249981
https://doi.org/10.1007/bf00249981
Publikováno v:
Canadian journal of microbiology. 32(7)
Aspergillus niger could utilize orcinol (5-methyl-resorcinol or 3,5-dihydroxytoluene) as the sole source of carbon and energy. In the first step of catabolism A. niger hydroxylates orcinol to form 2,3,5-trihydroxytoluene. Its oxidized form, 2-hydroxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbd364c89042b52233e0c8bcbdde79f
https://pubmed.ncbi.nlm.nih.gov/3742332
https://pubmed.ncbi.nlm.nih.gov/3742332
Autor:
S R, Sahasrabudhe, V V, Modi
Publikováno v:
Biochemistry international. 10(4)
Comparison of the properties of a purified benzoate-4-hydroxylase, using benzoic acid and its chlorinated derivatives as substrate, suggests that the same enzyme operates during the initial hydroxylation of benzoate, 2-chlorobenzoate (2-cba), and 3-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff3003616f501f631270c81a3157b970
https://pubmed.ncbi.nlm.nih.gov/4026866
https://pubmed.ncbi.nlm.nih.gov/4026866
Autor:
S R, Sahasrabudhe, V V, Modi
Publikováno v:
Microbiological sciences. 4(10)
Many microorganisms are capable of utilizing anthropogenic chloroaromatics as the sole source of carbon and energy. Techniques of co-cultivation, conjugation, and in vitro cloning have been used to extend the range of haloaromatic degradation in bact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f19c3d50edd4e15b212296920add226
https://pubmed.ncbi.nlm.nih.gov/3153591
https://pubmed.ncbi.nlm.nih.gov/3153591