Zobrazeno 1 - 10
of 11
pro vyhledávání: '"S R, Newcom"'
Publikováno v:
Blood. 75:2434-2437
High molecular weight transforming growth factor-beta (TGF beta) is a physiologically active TGF secreted by nodular sclerosing Reed- Sternberg cells. Five monoclonal murine antibodies were prepared that distinguished Hodgkin's TGF beta from platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3b9a61eb6fb1693e62815cd700d556
https://doi.org/10.1182/blood.v75.12.2434.bloodjournal75122434
https://doi.org/10.1182/blood.v75.12.2434.bloodjournal75122434
Autor:
S R, Newcom
Publikováno v:
The American journal of the medical sciences. 312(3)
Two patients with stage IV poorly differentiated lymphocytic lymphoma became refractory to intensive combination chemotherapy that contained intermittent corticosteroids. Both patients had evidence of bone marrow replacement and leukemia. Continuous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ffe60d4c62e9b50942e8502a967a1ed6
https://pubmed.ncbi.nlm.nih.gov/8783682
https://pubmed.ncbi.nlm.nih.gov/8783682
Autor:
S R Newcom, L Gu
Publikováno v:
Journal of clinical pathology. 48(2)
AIMS--To determine the cellular origin of the most potent cytokine present in Hodgkin's disease, transforming growth factor (TGF) beta, the polycellular population of Hodgkin's tissue was studied using in situ hybridisation. METHODS--A biotin labelle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f34aee5293b8399b23ebd25562a2e6
https://pubmed.ncbi.nlm.nih.gov/7745117
https://pubmed.ncbi.nlm.nih.gov/7745117
Autor:
S R, Newcom, K K, Tagra
Publikováno v:
Cancer research. 52(24)
To measure the in vivo secretion of high molecular weight (HMW) transforming growth factor (TGF)beta by Reed-Sternberg cells from patients with nodular sclerosing Hodgkin's disease, we studied the urine samples from untreated patients. The urinary pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89404ab4e35d2c206c01a645da7ecf3a
https://pubmed.ncbi.nlm.nih.gov/1458464
https://pubmed.ncbi.nlm.nih.gov/1458464
Publikováno v:
The American journal of pathology. 140(3)
Activated lymphocytes and malignant lymphoma cells derived from them (Ki-1 positive lymphoma cells) share similar mechanisms of proliferation. To further examine the inhibitory role of endogenous transforming growth factor beta (TGF beta) in Ki-1 pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b00dc31e4cbfdf50b0771a89a2ac527
https://pubmed.ncbi.nlm.nih.gov/1312308
https://pubmed.ncbi.nlm.nih.gov/1312308
Publikováno v:
Blood. 79(1)
Recent evidence indicates that Reed-Sternberg (RS) cells from many cases of Hodgkin's disease have features of activated lymphocytes and that lymphokines from activated lymphocytes induce proliferation of L-428 RS cells. It is shown here that a lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63a1d2bb32d4eab021cc35c7d478aa79
https://pubmed.ncbi.nlm.nih.gov/1728308
https://pubmed.ncbi.nlm.nih.gov/1728308
Autor:
S R, Newcom
Publikováno v:
The Journal of laboratory and clinical medicine. 105(2)
Cell cultures were established from lymph nodes from eight patients with nodular sclerosing Hodgkin's disease and 12 controls. The patient cultures were demonstrated to produce a transforming growth factor for fibroblasts; none of the control culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c22f4f6bad0e2ee562a0cc49d6ed7425
https://pubmed.ncbi.nlm.nih.gov/3871830
https://pubmed.ncbi.nlm.nih.gov/3871830
Autor:
S R, Newcom, L, O'Rourke
Publikováno v:
Blood. 60(1)
Cell cultures were established from 8 lymph nodes replaced by nodular sclerosing Hodgkin's disease. Serum-containing and serum-free conditioned media from these cultures potentiated fibroblast growth and were found to be consistently more potent than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::942531e2931ac5edc5aa36757bbd399c
https://pubmed.ncbi.nlm.nih.gov/6211204
https://pubmed.ncbi.nlm.nih.gov/6211204
Autor:
S R, Newcom, L, O'Rourke
Publikováno v:
Cancer. 49(11)
Recent work demonstrates that transformed cells can produce mitogenic agents capable of stimulating fibroblast proliferation. Also, work with normal cells and tissue has recently demonstrated that, among other cells, macrophages and platelets contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1116fd4e46dd22e7fb19b6a86cbc5e71
https://pubmed.ncbi.nlm.nih.gov/6280839
https://pubmed.ncbi.nlm.nih.gov/6280839
Publikováno v:
Lancet (London, England). 2(7873)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c3adf8aa61f8536cf60599f77bd6501
https://pubmed.ncbi.nlm.nih.gov/4135566
https://pubmed.ncbi.nlm.nih.gov/4135566