Zobrazeno 1 - 3
of 3
pro vyhledávání: '"S R, Mullapudi"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(5)
We used isogenic human tumor cell lines to investigate the specific and direct effects of wild-type (wt) p53 on the expression of O(6)-methylguanine-DNA methyltransferase (MGMT), a DNA repair protein that confers tumor resistance to many anticancer a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f0401467f6c88833286c6b4c2a9cdea
https://pubmed.ncbi.nlm.nih.gov/11350911
https://pubmed.ncbi.nlm.nih.gov/11350911
Publikováno v:
The Biochemical journal.
We showed recently that human O(6)-alkylguanine-DNA alkyltransferase (AGT), an important target for improving cancer chemotherapy, is a phosphoprotein and that phosphorylation inhibits its activity [Srivenugopal, Mullapudi, Shou, Hazra and Ali-Osman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43f127d6439a49f04462b7b135c9a1a8
https://pubmed.ncbi.nlm.nih.gov/11023825
https://pubmed.ncbi.nlm.nih.gov/11023825
Publikováno v:
Cancer research. 60(2)
The biochemical regulation of human O6-alkylguanine-DNA alkyltransferase (AGT), which determines the susceptibility of normal tissues to methylating carcinogens and resistance of tumor cells to many alkylating agents, is poorly understood. We investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::823ecd1b1e9001765be3bb216d54cf75
https://pubmed.ncbi.nlm.nih.gov/10667577
https://pubmed.ncbi.nlm.nih.gov/10667577