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of 10
pro vyhledávání: '"S R, McKercher"'
Publikováno v:
Molecular and Cellular Biology. 12:368-378
PU.1 is a B-cell- and macrophage-specific transcription factor. By an electrophoretic mobility shift assay and dimethyl sulfate methylation interference assays, we show that PU.1 binds to DNA sequences within the immunoglobulin kappa 3' enhancer (kap
Autor:
Michael L. Atchison, M. J. Klemsz, Sujatha Nagulapalli, S. R. Mckercher, R. A. Maki, Jm. R. Pongubala
Publikováno v:
Molecular and Cellular Biology. 12:368-378
PU.1 is a B-cell- and macrophage-specific transcription factor. By an electrophoretic mobility shift assay and dimethyl sulfate methylation interference assays, we show that PU.1 binds to DNA sequences within the immunoglobulin kappa 3' enhancer (kap
Autor:
Jeanne F. Loring, Stephen Yip, S. R. McKercher, Evan Y. Snyder, Franz-Josef Mueller, Samia J. Khoury, Jaime Imitola
Publikováno v:
Opportunities and Challenges of the Therapies Targeting CNS Regeneration ISBN: 9783540240822
Neural stem and progenitor cells express a variety of receptors that enable them to sense and react to signals emanating from physiological and pathophysiological conditions in the brain as well as elsewhere in the body. Many of these receptors and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe6dcd5bcce73c9fb70ccc9dfeed8e12
https://doi.org/10.1007/3-540-27626-2_6
https://doi.org/10.1007/3-540-27626-2_6
Publikováno v:
Ernst Schering Research Foundation workshop. (53)
Neural stem and progenitor cells express a variety of receptors that enable them to sense and react to signals emanating from physiological and pathophysiological conditions in the brain as well as elsewhere in the body. Many of these receptors and w
Autor:
A M, Lichanska, C M, Browne, G W, Henkel, K M, Murphy, M C, Ostrowski, S R, McKercher, R A, Maki, D A, Hume
Publikováno v:
Blood. 94(1)
During mouse embryogenesis, macrophage-like cells arise first in the yolk sac and are produced subsequently in the liver. The onset of liver hematopoiesis is associated with the transition from primitive to definitive erythrocyte production. This rep
Publikováno v:
Blood. 93(9)
Mice homozygous for the disruption of the PU.1 (Spi-1) gene do not produce mature macrophages. In determining the role of PU.1 in macrophage differentiation, the present study investigated whether or not there was commitment to the monocytic lineage
Publikováno v:
Blood. 91(10)
The ets family transcription factor PU.1 is expressed in monocytes/macrophages, neutrophils, mast cells, B cells, and early erythroblasts, but not in T cells. We have recently shown that PU.1 gene disruption results in mice with no detectable monocyt
Autor:
S R, McKercher, B E, Torbett, K L, Anderson, G W, Henkel, D J, Vestal, H, Baribault, M, Klemsz, A J, Feeney, G E, Wu, C J, Paige, R A, Maki
Publikováno v:
The EMBO journal. 15(20)
PU.1 is a member of the ets family of transcription factors and is expressed exclusively in cells of the hematopoietic lineage. Mice homozygous for a disruption in the PU.1 DNA binding domain are born alive but die of severe septicemia within 48 h. T
Publikováno v:
Blood. 88(8)
Transcription factors play an important role choreographing lineage commitment and expansion of blood cells. Nuclear factors that are expressed primarily or exclusively in hematopoietic cells are likely candidates for regulating blood cell developmen
Autor:
S. R. McKercher, G. Jahangiri, C. G. Putney, E. J. Mathur, Manouchehr M. Shahbaz, Charles E. Grimshaw
Publikováno v:
Biochemistry. 28(13)
Aldose reductase, purified to homogeneity from bovine kidney, is converted in a temperature-dependent process from a low-Km/low-Vmax form to a high-Km/high-Vmax form of the enzyme. Activation, which results in significant changes in the protein secon