Zobrazeno 1 - 8
of 8
pro vyhledávání: '"S R, Magnuson"'
Autor:
Terry J. Opgenorth, Jinshyun R. Wu-Wong, W. J. Chiou, S. Sundy, S R Magnuson, Douglas B. Dixon
Publikováno v:
Endothelium. 5:179-189
The human type-B endothelin receptor (h-ETB) was cloned from human lung poly A+RNA and stably expressed in CHO cells. Endothelin (ET) receptor binding and stimulation of PI hydrolysis demonstrated that the cloned h-ETB receptor is functional and link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216bb587fb0728ce941bc512fa36a666
https://doi.org/10.3109/10623329709053397
https://doi.org/10.3109/10623329709053397
Publikováno v:
The pharmacogenomics journal. 3(1)
The present study successfully utilizes a new ADME Rat Expression Bioarray, containing 1040 metabolism- and toxicology-linked genes, to monitor gene expression from the livers of rats treated with carbon tetrachloride (CCl(4)). Histopathological anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d5cb9321ab28d16b3af1ef26348cce
https://pubmed.ncbi.nlm.nih.gov/12815361
https://pubmed.ncbi.nlm.nih.gov/12815361
Publikováno v:
Receptorssignal transduction. 7(3)
Endothelins (ETs) are 21-amino acid peptides that bind to membrane receptors to initiate pathophysiological effects. This report characterizes ET receptors in benign prostatic hyperplasia-1 (BPH-1) cells, a prostate cell line isolated from a specimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f20c725ef591b7d9f5fb41e1521c5668
https://pubmed.ncbi.nlm.nih.gov/9440503
https://pubmed.ncbi.nlm.nih.gov/9440503
Autor:
J B, Nelson, W H, Lee, S H, Nguyen, D F, Jarrard, J D, Brooks, S R, Magnuson, T J, Opgenorth, W G, Nelson, G S, Bova
Publikováno v:
Cancer research. 57(1)
Production of the potent vasoconstrictor endothelin-1 (ET-1) by human prostate cancer cells accompanies prostate cancer progression in vivo. The predominant endothelin receptor expressed by normal prostate epithelium, ETB, is not expressed by any of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d171640248dbbca85602f13188a13f7c
https://pubmed.ncbi.nlm.nih.gov/8988036
https://pubmed.ncbi.nlm.nih.gov/8988036
Autor:
J B, Nelson, K, Chan-Tack, S P, Hedican, S R, Magnuson, T J, Opgenorth, G S, Bova, J W, Simons
Publikováno v:
Cancer research. 56(4)
The potent vasoconstrictor endothelin-1 (ET-1) is at its highest concentration in the normal human ejaculate and is associated with the progression of metastatic prostate cancer. ET-1 protein expression is detected in situ in 14 of 14 primary cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07cb9a372f63099745fc9bba23d0a8f5
https://pubmed.ncbi.nlm.nih.gov/8630991
https://pubmed.ncbi.nlm.nih.gov/8630991
Autor:
T J, Opgenorth, A L, Adler, S V, Calzadilla, W J, Chiou, B D, Dayton, D B, Dixon, L J, Gehrke, L, Hernandez, S R, Magnuson, K C, Marsh, E I, Novosad, T W, Von Geldern, J L, Wessale, M, Winn, J R, Wu-Wong
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 276(2)
Endothelins (ET) are potent vasoactive peptides implicated in the pathogenesis of a number of vascular diseases. The effects of ET on mammalian organs and cells are initiated by binding to ETA or ETB receptors. In this report, we document the pharmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::499edc3eb7e73ef7350dff8b42ee2d51
https://pubmed.ncbi.nlm.nih.gov/8632312
https://pubmed.ncbi.nlm.nih.gov/8632312
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 274(1)
Endothelin (ET) receptor in human astrocytoma U373MG cells was characterized. ET-1, ET-3, sarafotoxin S6C, IRL1620, BQ788, Ro46-2005 and PD142893 inhibited specific [125I]ET-1 binding with Ki values of 0.03 0.06, 0.74, 5.01, 4.45, 2275 and 157 nM, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66d45b53256f284817c574af1ef4427d
https://pubmed.ncbi.nlm.nih.gov/7616437
https://pubmed.ncbi.nlm.nih.gov/7616437
Publikováno v:
Molecular pharmacology. 44(2)
Recently the identification of endothelin (ET) receptors and ET in the pituitary gland has induced much interest in studying the potential role of ET in neuroendocrine regulation. MMQ, isolated from rat pituitary, is a prolactin-secreting cell line.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32d48cf19605556c2200649e80907a07
https://pubmed.ncbi.nlm.nih.gov/8355666
https://pubmed.ncbi.nlm.nih.gov/8355666