Zobrazeno 1 - 10
of 31
pro vyhledávání: '"S R, Husain"'
Autor:
S. R. Husain, Mohammad Ali
Publikováno v:
International Journal of Energy Research. 17:697-708
A numerical investigation has been carried out on natural convective heat transfer and fluid flow in a square cavity with vee-corrugated vertical surfaces. This study covers the range of corrugation frequency from 1 to 3 and Grashof number from 103 t
Publikováno v:
Numerical Heat Transfer, Part B: Fundamentals. 16:31-58
The vorticity-streamfunction formulation is implemented on the control-volume-based finite-element method (CVFEM). The key contribution of this work is the formulation of the wall vorticity, which allows successful modeling of fluid flow problems wit
Publikováno v:
International journal of cancer. 92(2)
Surgery, radiotherapy and chemotherapy have minimally altered survival of glioblastoma patients. We explored a specific approach for glioblastoma therapy in which cellular interleukin-13 (IL-13) receptors were targeted by an IL-13 cytotoxin. A wide a
Autor:
S R, Husain, R K, Puri
Publikováno v:
Blood. 95(11)
Clinically advanced and rapidly progressive AIDS-associated Kaposi sarcoma (AIDS-KS) tumors require an aggressive tumor-directed therapy. We have observed that AIDS-KS cells express high levels of receptors for immune regulatory cytokine, interleukin
Complete regression of established human glioblastoma tumor xenograft by interleukin-4 toxin therapy
Publikováno v:
Cancer research. 58(16)
No curative therapy is available for malignant gliomas. We have discovered that human glioblastoma cells express high affinity interleukin-4 receptor (IL-4R), which is an attractive target for receptor-directed IL-4 toxin therapy. The IL-4 toxin, IL-
Publikováno v:
Molecular medicine (Cambridge, Mass.). 3(5)
BACKGROUND: AIDS-associated Kaposi's sarcoma (AIDS-KS) represents one of the most common malignancies associated with human immunodeficiency virus infection. To target effective therapeutic agents to AIDS-KS, we have identified a new target in the fo
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(2)
AIDS-associated Kaposi's sarcoma (AIDS-KS), the most common malignant complication of human immunodeficiency virus infection, is characterized by neoplastic proliferation of mesenchymal cells. AIDS-KS cells release and respond to an array of cytokine
Publikováno v:
Oncology research. 9(9)
We have investigated the expression of interleukin-4 receptors (IL-4R) in acquired immunodeficiency syndrome (AIDS)-related Kaposi's Sarcoma (KS) in situ by immunohistochemistry. Frozen and fixed sections from five patch stage and two nodular stage K
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(10)
Interleukin-13 (IL-13) is a cytokine produced primarily by activated T lymphocytes. It exerts a variety of effects on different cell types, including monocytes, B lymphocytes, mast cells, and keratinocytes. The effects of IL-13 on target cells are of
Publikováno v:
Cellular immunology. 171(1)
We have previously demonstrated that a chimeric protein composed of human IL-4 and Pseudomonas exotoxin, termed IL4-PE4E, is cytotoxic to primary cells derived from human renal cell carcinoma (RCC). To improve the cytotoxicity of IL4-toxins such as I