Zobrazeno 1 - 10
of 22
pro vyhledávání: '"S R, George"'
Publikováno v:
Cerebral Cortex. 19:153-164
The 22q11.2 deletion syndrome (22qDS) is the most common microdeletion syndrome in humans. Its multisystem manifestations include congenital anomalies and neuropsychiatric disorders such as schizophrenia. Structural neuroimaging shows various abnorma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c8002c422d5f366cf90100dc498396
https://doi.org/10.1093/cercor/bhn066
https://doi.org/10.1093/cercor/bhn066
Publikováno v:
British journal of pharmacology. 161(5)
µ- and δ-opioid receptors form heteromeric complexes with unique ligand binding and G protein-coupling profiles linked to G protein α z-subunit (Gα(z) ) activation. However, the mechanism of action of agonists and their regulation of the µ-δ re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbe8dfc2e7349c6d9ee6b00e3a42b611
https://pubmed.ncbi.nlm.nih.gov/20977461
https://pubmed.ncbi.nlm.nih.gov/20977461
Autor:
Rachel F. Tyndale, E H Cook, T Nguyen, Edward M. Sellers, M D Thompson, Brian F. O'Dowd, D Zarrabian, George R. Uhl, D E Comings, S R George, David J. Vandenbergh, Matthew D. Krasowski, E Bendahhou
Publikováno v:
Molecular psychiatry. 5(3)
The dopamine transporter (DAT) provides major regulation of the synaptic levels of dopamine and is a principal target of psychostimulant drugs. Associations between DAT gene polymorphisms and human disorders with possible links to dopaminergic neurot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812642e5f199d4698e271209956c0b8c
https://pubmed.ncbi.nlm.nih.gov/10889531
https://pubmed.ncbi.nlm.nih.gov/10889531
Publikováno v:
The Journal of biological chemistry. 275(34)
The existence of dimers and oligomers for many G protein-coupled receptors has been described by us and others. Since many G protein-coupled receptor subtypes are highly homologous to each other, we examined whether closely related receptors may inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c6df5b653e33eb01f8465ec579da1a4
https://pubmed.ncbi.nlm.nih.gov/10842167
https://pubmed.ncbi.nlm.nih.gov/10842167
Publikováno v:
Molecular pharmacology. 57(4)
Two G protein-coupled receptors (Edg-2) and (Edg-4) for the lysolipid phosphoric acid mediator lysophosphatidic acid have been described by molecular cloning. However, the calcium-mobilizing receptor Edg-4 is not expressed in some cell lines that exh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b11d00929fd138ffd3627ea2f98c3ae
https://pubmed.ncbi.nlm.nih.gov/10727522
https://pubmed.ncbi.nlm.nih.gov/10727522
Publikováno v:
The Journal of biological chemistry. 274(39)
The mu opioid receptor (MOR) has been shown to desensitize after 1 h of exposure to the opioid peptide, [D-Ala(2), N-MePhe(4), Gly-ol(5)]enkephalin (DAMGO), largely by the loss of receptors from the cell surface and receptor down-regulation. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ece87fac18e4b5d7a879ccbe2a59c0bb
https://pubmed.ncbi.nlm.nih.gov/10488100
https://pubmed.ncbi.nlm.nih.gov/10488100
Publikováno v:
American journal of medical genetics. 81(3)
We report a single stranded conformational polymorphism (SSCP) analysis of the coding region of the dopamine D1 receptor (DRD1) in Tourette's syndrome (n = 50) and control (n = 50) subjects. Tourette's syndrome populations with comorbidity for attent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ec7368d0db55b50a7337a15dfe09ca1
https://pubmed.ncbi.nlm.nih.gov/9603612
https://pubmed.ncbi.nlm.nih.gov/9603612
Publikováno v:
Endocrinology. 138(10)
Dopamine D2 receptor agonists are commonly used in the control of PRL-secreting adenomas, and the sensitivity of dopamine agonists during long term therapy is exquisite. However, the molecular mechanisms responsible for the maintenance of this cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38edf186e82356bb0f1a0a34469b4094
https://pubmed.ncbi.nlm.nih.gov/9322930
https://pubmed.ncbi.nlm.nih.gov/9322930
Publikováno v:
Molecular pharmacology. 50(5)
The effects of acute exposure of the opioid peptide [D-Ala2,N-MePhe4, Gly-ol5]enkephalin (DAMGO) on the mu-opioid receptor were examined in Chinese hamster ovary (CHO) K-1 and baby hamster kidney stable transfectants. In the CHO cell line, acute 1-hr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f791f3fd896346fe9b77dc00df852d6
https://pubmed.ncbi.nlm.nih.gov/8913353
https://pubmed.ncbi.nlm.nih.gov/8913353
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 43(5)
A c-myc epitope-tagged human dopamine D1 receptor (c-myc D1 receptor) was expressed in Sf9 cells and its cellular distribution under basal conditions and after exposure to the agonist dopamine was examined. In the basal state, immunofluorescently lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f038a7c5dd095cd114ad99a76d68a1
https://pubmed.ncbi.nlm.nih.gov/7730588
https://pubmed.ncbi.nlm.nih.gov/7730588