Zobrazeno 1 - 10
of 366
pro vyhledávání: '"S Putnam"'
Autor:
Phyllis Chan, Han Ting Ding, Bianca M. Liederer, Jialin Mao, Paula Belloni, Liuxi Chen, Simon S. Gao, Victory Joseph, Xiaoying Yang, Joseph S. Lin, Mayur S. Mitra, Wendy S. Putnam, Angelica Quartino, Rebecca N. Bauer, Lin Pan
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1945-1954 (2021)
Abstract GDC‐0334 is a novel small molecule inhibitor of transient receptor potential cation channel member A1 (TRPA1), a promising therapeutic target for many nervous system and respiratory diseases. The pharmacokinetic (PK) profile and pharmacody
Externí odkaz:
https://doaj.org/article/38338915571446a38eeb11b03b47d34b
Autor:
Stanley J. Szefler, Graham Roberts, Adalberto S. Rubin, Stefan Zielen, Piotr Kuna, Oral Alpan, Judith Anzures‐Cabrera, Qiang Chen, Cécile T. J. Holweg, Janusz Kaminski, Wendy S. Putnam, John G. Matthews, Nikhil Kamath
Publikováno v:
Clinical and Translational Allergy, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Background Lebrikizumab is a monoclonal antibody that modulates activity of interleukin‐13. The Phase 3 ACOUSTICS study assessed lebrikizumab efficacy and safety in adolescents with uncontrolled asthma despite standard‐of‐care treatmen
Externí odkaz:
https://doaj.org/article/95330c9a733f48b0baef545bd3c87bf6
Autor:
Sarah J. Schrieber, Wendy S. Putnam, Edwin Chiu Yuen Chow, Jacek Cieslak, Yanli Zhuang, Steven W. Martin, Paul Hanson, Frank Maggio, Leslie A. Rivera Rosado
Publikováno v:
Drugs in R&D, Vol 20, Iss 4, Pp 301-306 (2020)
Abstract Expedited development programs for biological products to be used in the treatment of serious conditions bring about challenges because of the compressed clinical development timeframes. As expedited development does not lessen the quality e
Externí odkaz:
https://doaj.org/article/a3da12607df14469b1768c5c0151d180
Akademický článek
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Autor:
Han Ting Ding, Wendy S. Putnam, Simon S. Gao, Joseph Lin, Bianca M. Liederer, Jialin Mao, Angelica Quartino, Victory Joseph, Xiaoying Yang, Liuxi Chen, Paula Belloni, Phyllis Chan, Rebecca N. Bauer, Mayur S. Mitra, Lin Pan
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1945-1954 (2021)
Clinical and Translational Science
Clinical and Translational Science
GDC‐0334 is a novel small molecule inhibitor of transient receptor potential cation channel member A1 (TRPA1), a promising therapeutic target for many nervous system and respiratory diseases. The pharmacokinetic (PK) profile and pharmacodynamic (PD
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
D.J. Agriantonis, A. Graif, G. Kimbiris, Mark J. Garcia, Christelle Chedrawy, C. Grilli, S. Putnam, D. Leung
Publikováno v:
CardioVascular and Interventional Radiology. 44:558-564
To evaluate the safety and effectiveness of the Protege nitinol self-expanding stent for the treatment of iliofemoral veno-occlusive disease. A retrospective review was performed of 376 (284 left, 92 right) Protege stents in 212 limbs of 183 patients
Publikováno v:
American family physician. 105(4)
Venous thromboembolism (VTE) recurrence rates are three times higher in patients with chronic or no risk factors compared with those who have transient risk factors after stopping anticoagulation therapy. In patients with unprovoked VTE, age-appropri
Autor:
Kathryn Mesh, Kun Peng, John G. Matthews, Prescott G. Woodruff, Wendy S. Putnam, Melissa Gonzalez Edick, Elliot Israel, Peter Bradding, Margaret Solon, Francis Abreu, Arnaud Bourdin, Kit Wong, Monet Howard, Monica Kraft, Cecile T.J. Holweg, Joseph R. Arron, Cary D. Austin, J. Mark FitzGerald, Gail M. Gauvreau, David F. Choy, Fang Cai, Ronald E. Ferrando, Lief Bjermer, Miriam Baca, Julie Olsson, Clavier Investigators, Kaharu Sumino
Publikováno v:
Clinical and Experimental Allergy
Clinical and Experimental Allergy, Wiley, In press, ⟨10.1111/cea.13731⟩
Clinical and Experimental Allergy, In press, ⟨10.1111/cea.13731⟩
Clinical and Experimental Allergy, Wiley, In press, ⟨10.1111/cea.13731⟩
Clinical and Experimental Allergy, In press, ⟨10.1111/cea.13731⟩
Background The anti-interleukin 13 (IL-13) monoclonal antibody lebrikizumab improves lung function in patients with moderate-to-severe uncontrolled asthma, but its effects on airway inflammation and remodelling are unknown. CLAVIER was designed to as
Publikováno v:
Journal of Vascular and Interventional Radiology. 31:537-543
To examine the safety of therapeutic-dose anticoagulation during catheter-directed thrombolysis (CDT) for acute pulmonary embolism (PE).A retrospective review of 156 consecutive cases (age, 56.6 ± 15.4 years; 85 males) of CDT with alteplase for acut