Výsledky vyhledávání - "S Phase/*drug effects"

Bcl-2 blocks 2-methoxyestradiol induced leukemia cell apoptosis by a p27(Kip1)-dependent G1/S cell cycle arrest in conjunction with NF-kappaB activation

Autor: Batsi, C., Markopoulou, S., Kontargiris, E., Charalambous, C., Thomas, C., Christoforidis, S., Kanavaros, P., Constantinou, A. I., Marcu, K. B., Kolettas, E.

2-Methoxyestradiol (2-ME2) induces leukemia cells to undergo apoptosis in association with Bcl-2 inactivation but the mechanisms whereby Bcl-2 contributes to protection against programmed cell death in this context remain unclear. Here we showed that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10561::910d65207ed918752b5803f7d2216cff
http://olympias.lib.uoi.gr/jspui/handle/123456789/23528

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Vitamin C transiently arrests cancer cell cycle progression in S phase and G2/M boundary by modulating the kinetics of activation and the subcellular localization of Cdc25C phosphatase

Autor: Thomas, C. G., Vezyraki, P. E., Kalfakakou, V. P., Evangelou, A. M.

Regulation of cell cycle progression involves redox (oxidation-reduction)-dependent modification of proteins including the mitosis-inducing phosphatase Cdc25C. The role of vitamin C (ascorbic acid, ASC), a known modulator of the cellular redox status

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10561::885db94970c543c71ff9b9f9de77a363
http://olympias.lib.uoi.gr/jspui/handle/123456789/24561

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Multiple forms of angiostatin induce apoptosis in endothelial cells

Autor: Lucas, R., Holmgren, L., Garcia, I., Jimenez, B., Mandriota, S. J., Borlat, F., Sim, B. K. L., Wu, Z., Georges Grau, Shing, Y., Soff, G. A., Bouck, N., Pepper, M. S.

Publikováno v: Scopus-Elsevier
Blood, Vol. 92, No 12 (1998) pp. 4730-4741

Angiostatin is a circulating inhibitor of angiogenesis generated by proteolytic cleavage of plasminogen. In this study we have used recombinant human and murine angiostatins (kringles 1-4) as well as native human angiostatin (prepared by elastase dig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4fbc051f9d5e395db6cdb6ab03d5f143
http://www.scopus.com/inward/record.url?eid=2-s2.0-17444390815&partnerID=MN8TOARS

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