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Autor:
S. Phaneuf, J Bradley, Michèle Bergeron, Francis Mandy, Atousa Shafaie, John L. Fahey, Nadia Soucy, T. Ding
Publikováno v:
Cytometry. 50:86-91
Background: Exceptionally robust cell preparations are needed for quality assessment programs (QAPs) such as the International Program for Quality Assessment and Standardization for Immunological Measures (QASI) relevant to HIV/AIDS. A suitable produ
Autor:
N. Soucy, T. Ding, Janet K.A. Nicholson, Andrew D. Badley, N. C.Hawley Foss, Michèle Bergeron, Francis Mandy, S. Phaneuf
Publikováno v:
Cytometry. 50:53-61
BACKGROUND In the past decade, human immunodeficiency virus (HIV) lymphocyte immunophenotyping has evolved significantly. New fluorochromes, new multicolor reagents, enhanced instruments, and the capacity to provide absolute cell counts using the sin
Publikováno v:
Reproduction. 120:91-97
Oxytocin is used widely for the induction and augmentation of labour, but there is little information about the dynamics of oxytocin receptors in human myometrium during parturition, and the possible effect of oxytocin infusion. This information is i
Publikováno v:
Journal of Endocrinology. 162:401-408
There is evidence for hormonal receptor desensitisation in human myometrium, but little is known about the mechanisms involved in the loss of myometrial response to agonists such as beta(2)-adrenergic agonists, prostaglandin gamma and oxytocin. It is
Autor:
Belén Rodríguez Liñares, María P. Carrasco, S Phaneuf, Ann Harris, Gergely Asbóth, Andrés López Bernal, Tadashi Kimura
Publikováno v:
Human Reproduction Update. 4:625-633
In the present study, we investigated the possible mechanisms by which oxytocin might regulate oxytocin receptor (OTR) density. Exposure of cultured myometrial cells to oxytocin for a prolonged period caused desensitization: the steady-state level of
Publikováno v:
Reproduction. 111:309-317
Prostaglandin F2 alpha (PGF2 alpha) has regulatory (mainly luteolytic) effects in the ovary but the mechanism of action is not completely understood. Reverse transcriptase-polymerase chain reaction (RT-PCR) techniques were used to demonstrate the pre
Autor:
G Asbóth, Ann Harris, María P. Carrasco, Fumitaka Saji, G N Europe-Finner, S Phaneuf, Tadashi Kimura, A. López Bernal
Publikováno v:
Journal of Endocrinology. 154:7-18
We have recently provided evidence for the desensitization of oxytocin receptors in human myometrial cells. In the present study, we have investigated the possible mechanisms by which oxytocin (OT) might regulate OT receptor density. The steady state
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 81:2098-2103
Although a physiological role for oxytocin during parturition is well accepted, the mechanisms by which it activates myometrial contractility during labor have not been completely elucidated. We have previously shown the presence of Gq and two pertus
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 81:2104-2110
The objective of this study was to investigate the mechanism of action of PGF2 alpha in cultured human myometrial cells. We measured the effects of PGF2 alpha and fluprostenol, a selective PGF2 alpha receptor (FP receptor) agonist, on phospholipase C