Zobrazeno 1 - 10
of 99
pro vyhledávání: '"S Paul Oh"'
Autor:
Simon Tual-Chalot, Marwa Mahmoud, Kathleen R Allinson, Rachael E Redgrave, Zhenhua Zhai, S Paul Oh, Marcus Fruttiger, Helen M Arthur
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98646 (2014)
Rare inherited cardiovascular diseases are frequently caused by mutations in genes that are essential for the formation and/or function of the cardiovasculature. Hereditary Haemorrhagic Telangiectasia is a familial disease of this type. The majority
Externí odkaz:
https://doaj.org/article/5d52fe5818944569bdd0265c10f358a5
Autor:
Sung O Park, Heather L Wamsley, Kyungmi Bae, Zhongbo Hu, Xiaomiao Li, Se-woon Choe, William B Slayton, S Paul Oh, Kay-Uwe Wagner, Peter P Sayeski
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59675 (2013)
Germline deletion of Jak2 in mice results in embryonic lethality at E12.5 due to impaired hematopoiesis. However, the role that Jak2 might play in late gestation and postnatal life is unknown. To understand this, we utilized a conditional knockout ap
Externí odkaz:
https://doaj.org/article/107094f9362e4f75bcb3a3f489558848
Autor:
Eun-Jung Choi, Yong Hwan Kim, Se-woon Choe, Yu Gyoung Tak, Eva M Garrido-Martin, Myron Chang, Young Jae Lee, S Paul Oh
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63138 (2013)
Hereditary Hemorrhagic Telangiectasia (HHT) is a genetic vascular disease in which arteriovenous malformations (AVMs) manifest in skin and multiple visceral organs. HHT is caused by heterozygous mutations in endoglin (ENG), activin receptor-like kina
Externí odkaz:
https://doaj.org/article/73e0d6d637c245668eb8248f394a17c3
Autor:
Stefano Farioli-Vecchioli, Daniele Saraulli, Marco Costanzi, Luca Leonardi, Irene Cinà, Laura Micheli, Michele Nutini, Patrizia Longone, S Paul Oh, Vincenzo Cestari, Felice Tirone
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8339 (2009)
Neurogenesis in the dentate gyrus of the adult hippocampus has been implicated in neural plasticity and memory, but the molecular mechanisms controlling the proliferation and differentiation of newborn neurons and their integration into the synaptic
Externí odkaz:
https://doaj.org/article/a49877fa8e204add946ce5fe8c9c7ded
Autor:
Bin Liu, Dan Yi, Jiakai Pan, Jingbo Dai, Maggie M. Zhu, You‐Yang Zhao, S. Paul Oh, Michael B. Fallon, Zhiyu Dai
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 1, Pp n/a-n/a (2022)
Abstract BMP signaling deficiency is evident in the lungs of patients with pulmonary arterial hypertension. We demonstrated that PHD2 deficiency suppresses BMP signaling in the lung endothelial cells, suggesting the novel mechanisms of dysregulated B
Externí odkaz:
https://doaj.org/article/e3e7950ab3e44c8f94406428c59d1d04
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance
Autor:
Joonseok Cho, Yujian Zhang, Shi-Young Park, Anna-Maria Joseph, Chul Han, Hyo-Jin Park, Srilaxmi Kalavalapalli, Sung-Kook Chun, Drake Morgan, Jae-Sung Kim, Shinichi Someya, Clayton E. Mathews, Young Jae Lee, Stephanie E. Wohlgemuth, Nishanth E. Sunny, Hui-Young Lee, Cheol Soo Choi, Takayuki Shiratsuchi, S. Paul Oh, Naohiro Terada
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Adenine nucleotide translocase (ANT) 2 promotes ADP/ATP exchange across the mitochondrial inner membrane. Choet al. show that liver specific Ant2 deletion increases uncoupled respiration and protects mice against fatty liver and obesity-induced insul
Externí odkaz:
https://doaj.org/article/27c33827aff94d8b88865b49e3ea384d
Autor:
Shwetal Mehta, Gregory H. Turner, Michael T. Lawton, S. Paul Oh, Candice L Nguyen, Ernesto Luna Melendez, Michael J. Lang, Chul Han
Publikováno v:
Journal of Neurosurgery. 137:163-174
OBJECTIVE Hereditary hemorrhagic telangiectasia is the only condition associated with multiple inherited brain arteriovenous malformations (AVMs). Therefore, a mouse model was developed with a genetics-based approach that conditionally deleted the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e20dfb5a9b3e1060301e613369b8d9
https://doi.org/10.3171/2021.6.jns21717
https://doi.org/10.3171/2021.6.jns21717
Autor:
Lea Scherschinski, Chul Han, Yong Hwan Kim, Ethan A. Winkler, Joshua S. Catapano, Tyler D. Schriber, Peter Vajkoczy, Michael T. Lawton, S. Paul Oh
Publikováno v:
Angiogenesis.
Background Longitudinal mouse models of brain arteriovenous malformations (AVMs) are crucial for developing novel therapeutics and pathobiological mechanism discovery underlying brain AVM progression and rupture. The sustainability of existing mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3128821f5d4246edcc8396cfa2a242e3
https://doi.org/10.1007/s10456-023-09881-w
https://doi.org/10.1007/s10456-023-09881-w
Autor:
Bin Liu, Dan Yi, Zhiyun Yu, Jiakai Pan, Karina Ramirez, Shuai Li, Ting Wang, Christopher C. Glembotski, Michael B. Fallon, S. Paul Oh, Mingxia Gu, Joanna Kalucka, Zhiyu Dai
Publikováno v:
Liu, B, Yi, D, Yu, Z, Pan, J, Ramirez, K, Li, S, Wang, T, Glembotski, C C, Fallon, M B, Oh, S P, Gu, M, Kalucka, J & Dai, Z 2022, ' TMEM100, a Lung-Specific Endothelium Gene ', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 42, no. 12, pp. 1495-1497 . https://doi.org/10.1161/ATVBAHA.122.317683
The heterogeneity of endothelium across different organs was recently explored using single-cell RNA-sequencing analysis. Compared to other organs, the lung exhibits a distinct structure composed of a thin layer of capillary for efficient gas exchang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44e9c903159c4b65dbe74fa134b1f42
https://doi.org/10.1161/atvbaha.122.317683
https://doi.org/10.1161/atvbaha.122.317683
Supplementary Figure 4 from Tnk1/Kos1 Knockout Mice Develop Spontaneous Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1dc99084637c229eae517d397ff17d2
https://doi.org/10.1158/0008-5472.22376340
https://doi.org/10.1158/0008-5472.22376340
