Zobrazeno 1 - 10
of 37
pro vyhledávání: '"S P Balk"'
Autor:
L, Poluben, Ch R, Bryke, Y, Hsu, O, Shumeiko, L, Neumerzhitska, B, Klimuk, L, Rybchenko, S, Klymenko, S P, Balk, P G, Fraenkel
Publikováno v:
Experimental oncology. 41(1)
To examine frequencies and spectrum of genomic alterations in Ukrainian patients diagnosed with primary myelofibrosis (PMF).We enrolled 30 Ukrainian patients diagnosed with PMF who were previously tested for usual mutations in mye-loproliferative neo
Publikováno v:
Oncogene. 33:2815-2825
The metabolic functions of androgen receptor (AR) in normal prostate are circumvented in prostate cancer (PCa) to drive tumor growth, and the AR also can acquire new growth-promoting functions during PCa development and progression through genetic an
Autor:
J C Koningsberger, A Chott, T Logtenberg, L J Wiegman, R S Blumberg, G P van Berge Henegouwen, S P Balk
Publikováno v:
The Journal of Immunology. 159:1775-1782
TCR expression by human fetal intestinal intraepithelial lymphocytes (ilELs) and intestinal lamina propria lymphocytes was analyzed to address whether T cell development occurs in human fetal intestine, the diversity of human fetal iIELs, and whether
Autor:
C S Probert, A D Christ, L J Saubermann, J R Turner, A Chott, D Carr-Locke, S P Balk, R S Blumberg
Publikováno v:
The Journal of Immunology. 158:1941-1948
The phenotype of T cells associated with the common bile duct (CBD) is unknown. We investigated the hypothesis that they behave like other intraepithelial lymphocytes (IEL). Thus, we sought to determine the phenotype, TCR repertoire, and epithelial r
Autor:
C S Probert, A Chott, J R Turner, L J Saubermann, A C Stevens, K Bodinaku, C O Elson, S P Balk, R S Blumberg
Publikováno v:
The Journal of Immunology. 157:3183-3191
It is increasingly recognized that chronic Ag exposure may lead to clonal expansions of T cells, including those within the peripheral blood. Inflammatory bowel disease is a chronic, multisystemic disease of unknown origin that predominantly affects
Publikováno v:
The Journal of Immunology. 156:3024-3035
The human intestine contains two populations of anatomically distinct T cells, intraepithelial lymphocytes and lamina propria lymphocytes (LPLs), both of which preferentially use the TCR-alpha beta. Recent studies of TCR alpha- and beta-chain usage b
Publikováno v:
The Journal of Immunology. 150:5144-5153
Intestinal intraepithelial lymphocytes (IEL) are a phenotypically distinct T cell population of unknown function. The majority of human intestinal IEL express the TCR-alpha beta, the CD8 accessory molecule, and the CD45RO Ag, suggesting that they are
Expression of a nonpolymorphic MHC class I-like molecule, CD1D, by human intestinal epithelial cells
Autor:
R S Blumberg, C Terhorst, P Bleicher, F V McDermott, C H Allan, S B Landau, J S Trier, S P Balk
Publikováno v:
The Journal of Immunology. 147:2518-2524
The human CD1 locus encodes three nonpolymorphic MHC class I-like cell surface glycoproteins, CD1a-c, which are expressed primarily by immature thymocytes. A mAb and antipeptide antiserum were utilized to determine the tissue distribution of a fourth
Publikováno v:
The Journal of Immunology. 146:768-774
The cDNA encoding the murine CD1.1 and CD1.2 gene products were isolated and their complete nucleotide sequence was determined. The nucleotide sequence and genomic organization of these molecules were similar to human CD1. The sequences in the alpha
Autor:
M A, Exley, N J, Bigley, O, Cheng, S M, Tahir, S T, Smiley, Q L, Carter, H F, Stills, M J, Grusby, Y, Koezuka, M, Taniguchi, S P, Balk
Publikováno v:
Journal of leukocyte biology. 69(5)
A subset of CD161 (NK1) T cells express an invariant Valpha14Jalpha281 TCR-alpha chain (Valpha(invt) T cells) and produce Th2 and Th1 cytokines rapidly in response to CD1d, but their physiological function(s) remain unclear. We have found that CD1d-r