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pro vyhledávání: '"S P, Fussey"'
Publikováno v:
Hepatology (Baltimore, Md.). 19(4)
Primary biliary cirrhosis is a chronic autoimmune disease in which serum autoantibodies against the mitochondrial 2-oxo acid dehydrogenase enzyme complexes (M2 antibodies) are regularly present. Molecular mimicry of host proteins by bacterial counter
Autor:
S P, Fussey, J G, Lindsay, C, Fuller, R N, Perham, S, Dale, O F, James, M F, Bassendine, S J, Yeaman
Publikováno v:
Hepatology (Baltimore, Md.). 13(3)
Six components of the mammalian 2-oxo acid dehydrogenase complexes have previously been identified as M2 autoantigens in primary biliary cirrhosis. In this report, we present data showing that both polypeptide-specific and cross-reacting antibodies a
Publikováno v:
Gastroenterology. 99(6)
Primary biliary cirrhosis is characterized by the presence of antimitochondrial antibodies. Recently, six of the autoantigens have been identified as components of the 2-oxo acid dehydrogenase multienzyme complexes located within mammalian mitochondr