Zobrazeno 1 - 10
of 40
pro vyhledávání: '"S P, Becerra"'
Autor:
Alexandra Bernardo-Colón, Lijin Dong, Mones Abu-Asab, Richard S. Brush, Martin-Paul Agbaga, S. Patricia Becerra
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 5, Pp 100358- (2023)
Photoreceptor cells express the patatin-like phospholipase domain-containing 2 (PNPLA2) gene that codes for pigment epithelium-derived factor receptor (PEDF-R) (also known as ATGL). PEDF-R exhibits phospholipase activity that mediates the neurotrophi
Externí odkaz:
https://doaj.org/article/e6edfbfcaeb9463cb8396dbeb2decb19
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Retinal and choroidal inflammatory lesions increase the levels of the pro-inflammatory cytokine interleukin-6 (IL-6). Pigment epithelium-derived factor (PEDF) has anti-inflammatory properties, but it is not known if it can prevent the production of I
Externí odkaz:
https://doaj.org/article/83d777ab535646b0b164fe11e7a88838
Autor:
Jessica S. Gutiérrez-Becerra, Daniela Gordillo-Bastidas, Paulina S. López-Aguirre, Erika V. Zañudo-Angulo, Joanna J. López-Sandoval
Publikováno v:
Revista Mexicana de Endocrinología, Metabolismo y Nutrición, Vol 9, Iss 2 (2022)
Background: Obesity is a growing problem around the world, and even more so in the Western population. At present, two different pandemics collided, an Eastern-infectious disease caused by the severe acute respiratory syndrome coronavirus 2 known as
Externí odkaz:
https://doaj.org/article/17971982fbdb4992a00afba35588f4b1
Autor:
Miguel Flores‐Bellver, Jason Mighty, Silvia Aparicio‐Domingo, Kang V. Li, Cui Shi, Jing Zhou, Hannah Cobb, Patrick McGrath, German Michelis, Patricia Lenhart, Ganna Bilousova, Søren Heissel, Michael J. Rudy, Christina Coughlan, Andrew E. Goodspeed, S. Patricia Becerra, Stephen Redenti, M. Valeria Canto‐Soler
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 13, Pp n/a-n/a (2021)
Abstract Age‐related macular degeneration (AMD) is a leading cause of blindness worldwide. Drusen are key contributors to the etiology of AMD and the ability to modulate drusen biogenesis could lead to therapeutic strategies to slow or halt AMD pro
Externí odkaz:
https://doaj.org/article/f4461325f8d6451f97d6779225925a12
Publikováno v:
MethodsX, Vol 7, Iss , Pp 101026- (2020)
Degeneration of the retina can lead ultimately to devastating irreversible vision loss, such as in inherited retinitis pigmentosa and age-related macular degeneration. Currently there is no cure to prevent retinal degeneration. Quantitative cell-base
Externí odkaz:
https://doaj.org/article/b5bc1149dc11466a8a44d7ecfb06b6bb
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a19b43683e996eeb915a631e1f035ece
https://doi.org/10.1096/fasebj.2022.36.s1.l7644
https://doi.org/10.1096/fasebj.2022.36.s1.l7644
Autor:
Yujuan Wang, Preeti Subramanian, Defen Shen, Jingsheng Tuo, S. Patricia Becerra, Chi-Chao Chan
Publikováno v:
ASN Neuro, Vol 5 (2013)
AMD (age-related macular degeneration) is a neurodegenerative disease causing irreversible central blindness in the elderly. Apoptosis and inflammation play important roles in AMD pathogenesis. PEDF (pigment epithelium-derived factor) is a potent neu
Externí odkaz:
https://doaj.org/article/2059a11a3b6344189500fca19101877b
Publikováno v:
FEBS Journal. 277:2192-2205
Pigment epithelium-derived factor (PEDF), a potent blocker of angiogenesis in vivo, and of endothelial cell migration and tubule formation, binds with high affinity to an as yet unknown protein on the surfaces of endothelial cells. Given that protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5c50a2da0165890b5b10824172f363d
https://doi.org/10.1111/j.1742-4658.2010.07641.x
https://doi.org/10.1111/j.1742-4658.2010.07641.x
Autor:
Stephanie Filleur, Emelyn H. Shroff, Tetiana Zaichuk, Dorina Veliceasa, Yelena Mirochnik, Olga V. Volpert, S. P. Becerra, Hanhua Huang, Maria S. Aymerich, Karl Volz, Thomas Nelius, Ronald L. Yap
Publikováno v:
Cancer Research. 65:5144-5152
Pigment epithelial-derived factor (PEDF), an angiogenesis inhibitor with neurotrophic properties, balances angiogenesis in the eye and blocks tumor progression. Its neurotrophic function and the ability to block vascular leakage is replicated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53723442fb556739595f8f0e792ddd83
https://doi.org/10.1158/0008-5472.can-04-3744
https://doi.org/10.1158/0008-5472.can-04-3744
Publikováno v:
Journal of Biological Chemistry. 274:31605-31612
Pigment epithelium-derived factor (PEDF) has neuronal differentiation and survival activity on retinoblastoma and cerebellar granule (CG) cells. Here, we investigated the presence of PEDF receptors on retinoblastoma Y-79 and CG cells. PEDF radiolabel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7171c4f3f8c14204d657b2711290ece6
https://doi.org/10.1074/jbc.274.44.31605
https://doi.org/10.1074/jbc.274.44.31605