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Publikováno v:
International Journal of Pharmacognosy and Pharmaceutical Sciences. 3:28-30
Autor:
M. Wahajuddin
P-glycoprotein (P-gp), encoded by the multidrug-resistance (MDR)-1 gene is one of the best studied efflux transporters that is linked to multidrug resistance in cancer chemotherapies. P-gp belongs to the ATP-binding cassette (ABC) transporter family