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Akademický článek

Genome-wide association analysis for β-hydroxybutyrate concentration in Milk in Holstein dairy cattle

Autor: S. Nayeri, F. Schenkel, A. Fleming, V. Kroezen, M. Sargolzaei, C. Baes, A. Cánovas, J. Squires, F. Miglior

Publikováno v: BMC Genetics, Vol 20, Iss 1, Pp 1-17 (2019)

Abstract Background Ketosis in dairy cattle has been shown to cause a high morbidity in the farm and substantial financial losses to dairy farmers. Ketosis symptoms, however, are difficult to identify, therefore, the amount of ketone bodies (mainly �

Externí odkaz: https://doaj.org/article/16691048fdc548a08e923db56fb2221f

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Akademický článek

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P708 Ileal involvement defined by Montreal classification in Crohn’s disease is associated with a distinct microbial composition in ileal and colonic mucosa

Autor: C Hernandez-Rocha, S Nayeri, W Turpin, K Borowski, J Stempak, M S Silverberg

Publikováno v: Journal of Crohn's and Colitis. 16:i604-i606

Background The Montreal classification of inflammatory bowel disease (IBD) recognizes distinct subgroups based on location of disease, age at onset and behaviour for Crohn’s disease (CD) and extent in ulcerative colitis (UC). CD with ileal involvem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c062ca3c149c10a69656797b3d5b8b03
https://doi.org/10.1093/ecco-jcc/jjab232.829

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A161 MUCOSAL TRANSCRIPTOMICS IN NON-INFLAMED ILEUM OF CROHN’S DISEASE PATIENTS SHOWS DIFFERENTIALLY EXPRESSED GENE PROFILE COMPARED TO ILEUM OF HEALTHY CONTROLS

Autor: H Martinez-Lozano, S Nayeri, K Borowski, P A Olivera Sendra, H Leibovitzh, C Hernandez-Rocha, S Lee, J Stempak, M S Silverberg

Publikováno v: Journal of the Canadian Association of Gastroenterology. 5:38-39

Background The terminal ileum is the most susceptible location to develop Crohn’s disease (CD) and therefore is a valuable tissue to investigate biological mechanisms underlying chronic inflammation. Gene expression is highly affected by the level

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78eadaad7618179177769000bf010ffe
https://doi.org/10.1093/jcag/gwab049.160

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A235 ILEAL MICROBIOME ALPHA DIVERSITY REMAINS LOWER IN ENDOSCOPICALLY AND HISTOLOGICALLY INACTIVE CROHN’S DISEASE COMPARED TO ULCERATIVE COLITIS OR HEALTHY CONTROLS

Autor: P A Olivera Sendra, K Borowski, S Nayeri, H Martinez-Lozano, H Leibovitzh, S Lee, C Hernandez-Rocha, M S Silverberg

Publikováno v: Journal of the Canadian Association of Gastroenterology. 5:126-127

Background Crohn’s disease (CD) has been associated with a lower alpha diversity when compared to ulcerative colitis (UC) patients and healthy controls (HC), which also depends on disease location and endoscopic activity. However, it is unclear whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ad823152f209feb4dcb3de1a98f7560
https://doi.org/10.1093/jcag/gwab049.234

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A156 MUCOSA-ASSOCIATED MICROBIOTA OF ILEOCOLONIC CROHN’S DISEASE PATIENTS IS DISTINCT FROM COLONIC CROHN’S DISEASE AND ULCERATIVE COLITIS PATIENTS INDEPENDENT OF BIOPSY SITE, ENDOSCOPIC INFLAMMATION AND HOST GENETICS

Autor: C Hernandez-Rocha, S Nayeri, W Turpin, K Borowski, J Stempak, M S Silverberg

Publikováno v: Journal of the Canadian Association of Gastroenterology. 5:31-32

Background Colonic IBD encompassing ulcerative colitis (UC) and isolated colonic Crohn’s disease (cCD) shows significant clinical, therapeutic response and genetic differences compared to ileocolonic CD (icCD). Elucidating the microbial signatures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12e93f3033c68f079ae6b687df0f71e5
https://doi.org/10.1093/jcag/gwab049.155

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P066 Lower serum concentration of sulfated bile acids is associated with Primary Sclerosing Cholangitis Inflammatory Bowel Disease comorbidity and advanced liver fibrosis

Autor: H Leibovitzh, S Nayeri, K Borowski, C Hernandez-Rocha, S H Lee, W Turpin, J Stempak, I Sandhu, R Milgrom, M I Smith, K Croitoru, G M Hirschfield, A Gulamhusein, M S Silverberg

Publikováno v: Journal of Crohn's and Colitis. 16:i173-i174

Background Primary sclerosing cholangitis associated Inflammatory bowel disease (PSC-IBD) carries significant morbidity risk. Alterations in bile acid profiles has been shown to modulate chronic inflammation in IBD, but data in PSC-IBD comorbidity is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1471f8ca8a055e9ec6f042e496d37480
https://doi.org/10.1093/ecco-jcc/jjab232.195

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