Zobrazeno 1 - 10 of 136 pro vyhledávání: '"S Nadaud"'
1
Akademický článek
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure
Autor: M. Flamant, N. Mougenot, E. Balse, L. Le Fèvre, F. Atassi, E. L. Gautier, W. Le Goff, M. Keck, S. Nadaud, C. Combadière, A. Boissonnas, C. Pavoine
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract We recently highlighted a novel potential protective paracrine role of cardiac myeloid CD11b/c cells improving resistance of adult hypertrophied cardiomyocytes to oxidative stress and potentially delaying evolution towards heart failure (HF)
Externí odkaz: https://doaj.org/article/77862c2added47309a8996ae9920ed7a
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2
Akademický článek
Species-dependent structural polymorphism of Y145Stop prion protein amyloid revealed by solid-state NMR spectroscopy
Autor: Theint Theint, Philippe S. Nadaud, Darryl Aucoin, Jonathan J. Helmus, Simon P. Pondaven, Krystyna Surewicz, Witold K. Surewicz, Christopher P. Jaroniec
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Prion diseases can be transmitted across species. Here the authors use solid-state NMR to study prion protein (PrP) amyloids from human, mouse and Syrian hamster and show that their structural differences are mainly governed by two residues, which he
Externí odkaz: https://doaj.org/article/9856d994aae14b16b75bab5e7b839972
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4
Somatic mutational landscape of extracranial arteriovenous malformations and phenotypic correlations
Autor: F.N. El Sissy, M. Wassef, B. Faucon, D. Salvan, S. Nadaud, F. Coulet, H. Adle‐Biassette, F. Soubrier, A. Bisdorff, M. Eyries
Publikováno v: Journal of the European Academy of Dermatology and Venereology : JEADVReferences. 36(6)
Somatic genetic variants may be the cause of extracranial arteriovenous malformations, but few studies have explored these genetic anomalies, and no genotype-phenotype correlations have been identified.The aim of the study was to characterize the som
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f54effd1cadbd540ee98478a12f1a50
https://pubmed.ncbi.nlm.nih.gov/35536170
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5
Protein-solvent interfaces in human Y145Stop prion protein amyloid fibrils probed by paramagnetic solid-state NMR spectroscopy
Autor: Philippe S. Nadaud, Yongjie Xia, Witold K. Surewicz, Krystyna Surewicz, Darryl Aucoin, Theint Theint, Christopher P. Jaroniec
Publikováno v: Journal of Structural Biology. 206:36-42
The C-terminally truncated Y145Stop variant of prion protein (PrP23-144), which is associated with heritable PrP cerebral amyloid angiopathy in humans and also capable of triggering a transmissible prion disease in mice, serves as a useful in vitro m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d2b893901bbb4e140727e799074c33
https://doi.org/10.1016/j.jsb.2018.04.002
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6
Structural Studies of Amyloid Fibrils by Paramagnetic Solid-State Nuclear Magnetic Resonance Spectroscopy
Autor: Charles D. Schwieters, Witold K. Surewicz, Dwaipayan Mukhopadhyay, Yongjie Xia, Philippe S. Nadaud, Krystyna Surewicz, Christopher P. Jaroniec, Theint Theint
Publikováno v: Journal of the American Chemical Society. 140:13161-13166
Application of paramagnetic solid-state NMR to amyloids is demonstrated, using Y145Stop human prion protein modified with nitroxide spin-label or EDTA-Cu(2+) tags as a model. By using sample preparation protocols based on seeding with pre-formed fibr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd06fdfb19ac7dae661a8d6c26699ef
https://doi.org/10.1021/jacs.8b06758
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7
13C and 15N chemical shift assignments of mammalian Y145Stop prion protein amyloid fibrils
Autor: Krystyna Surewicz, Philippe S. Nadaud, Theint Theint, Witold K. Surewicz, Christopher P. Jaroniec
Publikováno v: Biomolecular NMR Assignments. 11:75-80
The Y145Stop prion protein (PrP23–144), which has been linked to the development of a heritable prionopathy in humans, is a valuable in vitro model for elucidating the structural and molecular basis of amyloid seeding specificities. Here we report
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da62fa6060788f7d14e47ed787734e09
https://doi.org/10.1007/s12104-016-9723-6
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8
Moderated Poster session - Vascular26Identification of CMTM3 as a new pro-angiogenic factor essential for vessel stabilization27Regulation of pulmonary vascular PW1+ progenitor cells recruitment during early chronic hypoxia-induced vessel neomuscularization28Impaired interleukin-10 production in response to CpG and depletion of the regulatory CD19+CD24hiCD38hi B cell compartment in patients with coronary atherosclerosis29Inflammatory effects of serum amyloid A via TLR2 and TLR4 in vascular cells30Collagen cross-linking enzymes are involved in vascular smooth muscle cells calcification31miR-504 inhibits venous smooth muscle cell proliferation and migration by targeting LAMTOR132Diaphenous related formin 2 (DRF2) is essential for KLF2-induced resistance of endothelial cells to flow forces.33Inhibition of TGfb axis and renin-angiotensin system in human ascending aorta aneurysms
Autor: L Borges, R D Fontijn, Z Yan, E Jover, M Schuchardt, I E Dumitriu, F Dierick, I Chrifi, MM Brandt, C Cheng, DJGM Duncker, V Monceau, B Hoareau, N Mougenot, G Marazzi, D Sassoon, JS Hulot, F Soubrier, S Nadaud, P Baruah, S Dinkla, J Bullenkamp, JC Kaski, Y Tu, N Pruefer, M Toelle, S Chebli, W Zidek, M Van Der Giet, A Silvente, F Marin, C Rodriguez, J Martinez-Gonzalez, CM Puche, M Valdes, D Hernandez Romero, J Tan, L Yang, ET Valent, TA Leyen, R Szulcek, JM Baggen, D Geerts, GP Van Nieuw Amerongen, AJG Horrevoets, LAA Alvarenga, RSP Falcao, RR Dias, S Lacchini, PS Gutierrez, JB Michel
Publikováno v: Cardiovascular Research. 111:S4-S6
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::358910dec229a0bd984873fdd33c31c9
https://doi.org/10.1093/cvr/cvw133
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9
Rapid Quantitative Measurements of Paramagnetic Relaxation Enhancements in Cu(II)-Tagged Proteins by Proton-Detected Solid-State NMR Spectroscopy
Autor: Christopher P. Jaroniec, Dwaipayan Mukhopadhyay, Philippe S. Nadaud, Matthew D. Shannon
Publikováno v: The journal of physical chemistry letters. 8(23)
We demonstrate rapid quantitative measurements of site-resolved paramagnetic relaxation enhancements (PREs), which are a source of valuable structural restraints corresponding to electron-nucleus distances in the ~10–20 Å regime, in solid-state nu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c83ee164f2edc3ca27becdc36296f1
https://pubmed.ncbi.nlm.nih.gov/29148785
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10
Species-dependent structural polymorphism of Y145Stop prion protein amyloid revealed by solid-state NMR spectroscopy
Autor: Krystyna Surewicz, Theint Theint, Philippe S. Nadaud, Darryl Aucoin, Christopher P. Jaroniec, Simon P. Pondaven, Witold K. Surewicz, Jonathan J. Helmus
Publikováno v: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
One of the most puzzling aspects of the prion diseases is the intricate relationship between prion strains and interspecies transmissibility barriers. Previously we have shown that certain fundamental aspects of mammalian prion propagation, including
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6183154571ce5f8e1084ef2ea9264079
https://pubmed.ncbi.nlm.nih.gov/28963458
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