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INHIBITION OF NATURAL KILLER CELL ACTIVITY IN MICE TREATED WITH TOBACCO SPECIFIC CARCINOGEN NNK

Autor: S N, Goud, A M, Kaplan

Publikováno v: Journal of Toxicology and Environmental Health, Part A. 56:131-144

Among the different chemicals present in tobacco and tobacco smoke, 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone (NNK) is the most potent carcinogen. In the present study the immunosuppressive effect of NNK was investigated in laboratory animals by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64dee6e1d675ab405373cd500506f655
https://doi.org/10.1080/009841099158196

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Contribution of T Lymphocytes to the Development of Bleomycin-Induced Pulmonary Fibrosis

Autor: Alan M. Kaplan, Donald A. Cohen, S. N. Goud, Jian Zhu

Publikováno v: Annals of the New York Academy of Sciences. 796:194-202

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f884923bbb2cd2c68f4bc35bf734113d
https://doi.org/10.1111/j.1749-6632.1996.tb32581.x

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Effects of cigarette smoke on the antibody responses to thymic independent antigens from different lymphoid tissues of mice

Autor: Alan M. Kaplan, S N Goud, Bondada Subbarao

Publikováno v: Archives of Toxicology. 66:164-169

The influence of cigarette smoke on the humoral immune response of mice was investigated in lymphocytes derived from the spleen, bone marrow (BM) and mesenteric lymph nodes (MLN). Mice of the DBA/2J or C57BL/6 strain were exposed to cigarette smoke o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7943a5a5796d62d883c4d19c37852ef1
https://doi.org/10.1007/bf01974009

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Primary antibody responses to thymus-independent antigens in the lungs and hilar lymph nodes of mice

Autor: Bondada Subbarao, Alan M. Kaplan, S N Goud

Publikováno v: Infection and Immunity. 58:2035-2041

B lymphocytes from the pulmonary lymphoid tissues were stimulated with a variety of thymus-independent (TI) antigens by intratracheal (i.t.) immunization. Immune responses in the lungs and hilar lymph nodes (HLN), which are part of the localized lymp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976f7c4473b8ac42f89d28d98e50d9e7
https://doi.org/10.1128/iai.58.7.2035-2041.1990

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Immunologic alterations in bleomycin-treated mice: role of pulmonary fibrosis in the modulation of immune responses

Autor: S N Goud, J Zhu, A M Kaplan

Publikováno v: American journal of respiratory and critical care medicine. 153(6 Pt 1)

Among the side effects of bleomycin (BLM), a drug frequently used in the treatment of lymphomas and squamous-cell carcinomas, is pneumonitis with pulmonary fibrosis. The most prominent biochemical lesion associated with pulmonary fibrosis, a chronic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e0867456bcc5ca7e7c8e371638792b
https://pubmed.ncbi.nlm.nih.gov/8665057

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Rapid communication: effect of irradiation on lymphocyte proliferation and differentiation: potential of IL-6 in augmenting antibody responses in cultures of murine spleen cells

Autor: S N, Goud

Publikováno v: International journal of radiation biology. 67(4)

Ionizing radiation induces both quantitative and qualitative changes in the lymphoid cells of both man and experimental animals, including inhibition of antibody responses. However, the cellular basis of this immunological lesion is not clear. In the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d10724c20ba6dd6b586611969d96bb8
https://pubmed.ncbi.nlm.nih.gov/7738410

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Antibody responses to thymic independent antigens in the peripheral and mesenteric lymph nodes of mice

Autor: S N, Goud, A M, Kaplan, B, Subbarao

Publikováno v: Regional immunology. 3(1)

Differentiation of B lymphocytes from various peripheral lymph nodes (PLN) of mice was studied in the in vitro and in vivo conditions. Subcutaneous (SC) immunization in the foot pads with thymic independent (TI)-2 antigens such as polyvinyl pyrrolido

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::25ff2ee57816855c66bcaf1613df1a8c
https://pubmed.ncbi.nlm.nih.gov/2121216

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Differential responses of B cells from the spleen and lymph node to TNP-Ficoll

Autor: S N Goud, N Muthusamy, B Subbarao

Publikováno v: The Journal of Immunology. 140:2925-2930

Subcutaneous immunization with the thymus independent Ag, TNP-Ficoll, does not elicit plaque-forming cell response from the regional lymph node B cells even though a good response is obtained with the splenic B cells. Lymph node cells respond well to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef068f1aa92765aebcdd6a36caaca551
https://doi.org/10.4049/jimmunol.140.9.2925

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Genetic effects of microwave radiation in mice

Autor: M.S. Rao, P. P. Reddy, V K Saxena, M V Rani, S N Goud, O S Reddi

Publikováno v: Mutation Research Letters. 103:39-42

Micriwave radiations are being increasingly used in radar, space research, telecommunication, medicine and in ovens. Microwaves have been found to induce chromatid and chromosomal aberrations in human lymphocyte cultures [1], mice spermatogonia [8],

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b650602902b11f75a717d95aab7f05ef
https://doi.org/10.1016/0165-7992(82)90084-7

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