Zobrazeno 1 - 10
of 15
pro vyhledávání: '"S N Abraham"'
Publikováno v:
The Journal of Immunology. 156:1490-1496
The pivotal role of mast cells in allergic reactions and inflammatory processes is well established and recent studies have suggested that mast cells may also have a role in specific immune responses. Because mast cells have been shown to phagocytose
Publikováno v:
The Journal of Immunology. 152:1907-1914
Most studies of mast cells have been directed at their role in the pathophysiology of IgE-mediated allergic reactions with little recognition of their participation in bacterial infections. We report that mast cells can specifically bind FimH, a mann
Autor:
J S, Shin, S N, Abraham
Publikováno v:
Science (New York, N.Y.). 293(5534)
Autor:
R, Malaviya, S N, Abraham
Publikováno v:
Immunological reviews. 179
Mast cells are key elements of the immune system. These cells release a wide variety of pro-inflammatory mediators which are responsible for the pathophysiology of many allergic diseases. Recent studies, however, have shown that mast cells have the c
Publikováno v:
Advances in experimental medicine and biology. 485
Autor:
S N, Abraham, R, Malaviya
Publikováno v:
Advances in experimental medicine and biology. 479
Publikováno v:
Blood. 94(12)
Cathepsin G is a neutral serine protease that is highly expressed at the promyelocyte stage of myeloid development. We have developed a homologous recombination strategy to create a loss-of-function mutation for murine cathepsin G. Bone marrow derive
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(4)
Most studies of mast cells have been directed at their role in the pathophysiology of IgE-mediated allergic reactions with little recognition of their participation in bacterial infections. We report that mast cells can specifically bind FimH, a mann
Publikováno v:
The Journal of biological chemistry. 268(4)
Previous studies of type 1 fimbriae of Escherichia coli have implicated FimH, a minor subunit, as the determinant of its mannose binding property. Structure-function analysis of FimH has not been possible because of the difficulty in obtaining adequa
Publikováno v:
The Journal of Immunology. 142:992-998
Escherichia coli type 1 fimbriae contain in association with the major structural protein a lectin-like adhesin moiety that mediates attachment of E. coli to mannose-containing receptors on the surface of host cells. We have investigated the lymphocy