Zobrazeno 1 - 10
of 185
pro vyhledávání: '"S Muntean"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14317 (2023)
Potassium Channel Tetramerization Domain 5 (KCTD5) regulates diverse aspects of physiology, ranging from neuronal signaling to colorectal cancer. A key feature of KCTD5 is its self-assembly into multi-subunit oligomers that seemingly enables particip
Externí odkaz:
https://doaj.org/article/1a4bd2bebd6047ffa56c848280ad3ac1
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Autosomal dominant polycystic kidney disease (PKD) is a hereditary disorder affecting multiple organs, including the heart. PKD has been associated with many cardiac abnormalities including the arrhythmogenic remodeling in clinical evaluations. In ou
Externí odkaz:
https://doaj.org/article/f289db4cd2e44f1ab3d297ac61ed365e
Publikováno v:
The Scientific Bulletin of Electrical Engineering Faculty. 22:60-64
The goal of this paper is to present the benefits of digitalization and Internet of Things applied in various fields of industry, including in cereal reception bases. Using Waterfall Methodology, this article widely describes the project plan of a we
Autor:
Brian S. Muntean, Stefano Zucca, Courtney M. MacMullen, Maria T. Dao, Caitlin Johnston, Hideki Iwamoto, Randy D. Blakely, Ronald L. Davis, Kirill A. Martemyanov
Publikováno v:
Cell Reports, Vol 22, Iss 1, Pp 255-268 (2018)
Summary: Modulation of neuronal circuits is key to information processing in the brain. The majority of neuromodulators exert their effects by activating G-protein-coupled receptors (GPCRs) that control the production of second messengers directly im
Externí odkaz:
https://doaj.org/article/207ebaaf212843c9b8f60c16dd36bffd
Autor:
Laurie P Sutton, Brian S Muntean, Olga Ostrovskaya, Stefano Zucca, Maria Dao, Cesare Orlandi, Chenghui Song, Keqiang Xie, Kirill A Martemyanov
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000477 (2019)
The striatum plays a fundamental role in motor learning and reward-related behaviors that are synergistically shaped by populations of D1 dopamine receptor (D1R)- and D2 dopamine receptor (D2R)-expressing medium spiny neurons (MSNs). How various neur
Externí odkaz:
https://doaj.org/article/aa11db4ea136455e9a462b928d2d5b88
Autor:
Matthew V. Green, Thomas Pengo, Jonathan D. Raybuck, Tahmina Naqvi, Hannah M. McMullan, Jon E. Hawkinson, Ezequiel Marron Fernandez de Velasco, Brian S. Muntean, Kirill A. Martemyanov, Rachel Satterfield, Samuel M. Young, Stanley A. Thayer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Synapse loss and dendritic damage correlate with cognitive decline in many neurodegenerative diseases, underlie neurodevelopmental disorders, and are associated with environmental and drug-induced CNS toxicities. However, screening assays designed to
Externí odkaz:
https://doaj.org/article/696e303d6aaf4c8384cab892bc02e5d6
Allostatic Changes in the cAMP System Drive Opioid-Induced Adaptation in Striatal Dopamine Signaling
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 946-960.e2 (2019)
Summary: Opioids are powerful addictive agents that alter dopaminergic influence on reward signaling in medium spiny neurons (MSNs) of the nucleus accumbens. Repeated opioid exposure triggers adaptive changes, shifting reward valuation to the allosta
Externí odkaz:
https://doaj.org/article/88f042b9f99e4f1fb21414e375f91ed7
Akademický článek
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Akademický článek
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Autor:
Yasanandana S. Wijayasinghe, Meenakshi P. Bhansali, Maheshkumar R. Borkar, Ganesh U. Chaturbhuj, Brian S. Muntean, Ronald E. Viola, Pravin R. Bhansali
Publikováno v:
Journal of Medicinal Chemistry. 65:3706-3728
Glucose, the primary substrate for ATP synthesis, is catabolized during glycolysis to generate ATP and precursors for the synthesis of other vital biomolecules. Opportunistic viruses and cancer cells often hijack this metabolic machinery to obtain en