Zobrazeno 1 - 10
of 53
pro vyhledávání: '"S Moses Dennison"'
Autor:
Iga Kucharska, Špela Binter, Rajagopal Murugan, Stephen W Scally, Julia Ludwig, Katherine Prieto, Elaine Thai, Giulia Costa, Kan Li, Gillian Q Horn, Yevel Flores-Garcia, Alexandre Bosch, Taylor Sicard, John L Rubinstein, Fidel Zavala, S Moses Dennison, Georgia D Tomaras, Elena A Levashina, Paul Kellam, Hedda Wardemann, Jean-Philippe Julien
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010999 (2022)
Antibodies targeting the human malaria parasite Plasmodium falciparum circumsporozoite protein (PfCSP) can prevent infection and disease. PfCSP contains multiple central repeating NANP motifs; some of the most potent anti-infective antibodies against
Externí odkaz:
https://doaj.org/article/8c8d7d9367ac4e39a094144bab03ffbb
Autor:
Matthew Zirui Tay, Pinghuang Liu, LaTonya D Williams, Michael D McRaven, Sheetal Sawant, Thaddeus C Gurley, Thomas T Xu, S Moses Dennison, Hua-Xin Liao, Agnès-Laurence Chenine, S Munir Alam, M Anthony Moody, Thomas J Hope, Barton F Haynes, Georgia D Tomaras
Publikováno v:
PLoS Pathogens, Vol 12, Iss 8, p e1005817 (2016)
Emerging data support a role for antibody Fc-mediated antiviral activity in vaccine efficacy and in the control of HIV-1 replication by broadly neutralizing antibodies. Antibody-mediated virus internalization is an Fc-mediated function that may act a
Externí odkaz:
https://doaj.org/article/a15aa94eb38144acb39665e487ecd3ac
Autor:
Sampa Santra, Georgia D Tomaras, Ranjit Warrier, Nathan I Nicely, Hua-Xin Liao, Justin Pollara, Pinghuang Liu, S Munir Alam, Ruijun Zhang, Sarah L Cocklin, Xiaoying Shen, Ryan Duffy, Shi-Mao Xia, Robert J Schutte, Charles W Pemble Iv, S Moses Dennison, Hui Li, Andrew Chao, Kora Vidnovic, Abbey Evans, Katja Klein, Amit Kumar, James Robinson, Gary Landucci, Donald N Forthal, David C Montefiori, Jaranit Kaewkungwal, Sorachai Nitayaphan, Punnee Pitisuttithum, Supachai Rerks-Ngarm, Merlin L Robb, Nelson L Michael, Jerome H Kim, Kelly A Soderberg, Elena E Giorgi, Lily Blair, Bette T Korber, Christiane Moog, Robin J Shattock, Norman L Letvin, Joern E Schmitz, M A Moody, Feng Gao, Guido Ferrari, George M Shaw, Barton F Haynes
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005042 (2015)
HIV-1 mucosal transmission begins with virus or virus-infected cells moving through mucus across mucosal epithelium to infect CD4+ T cells. Although broadly neutralizing antibodies (bnAbs) are the type of HIV-1 antibodies that are most likely protect
Externí odkaz:
https://doaj.org/article/ac4067627074462ba826fe0932273e87
Autor:
Richard H.C. Huntwork, Kan Li, S. Munir Alam, Gillian Q. Horn, S. Moses Dennison, Georgia D. Tomaras
Publikováno v:
Gates Open Research, Vol 7 (2024)
Label-free techniques including Surface Plasmon Resonance (SPR) and Biolayer Interferometry (BLI) are biophysical tools widely used to collect binding kinetics data of bimolecular interactions. To efficiently analyze SPR and BLI binding kinetics data
Externí odkaz:
https://doaj.org/article/f4b13b8adadf451582e8703d9c6ff61c
Autor:
S Moses Dennison, Laura L Sutherland, Frederick H Jaeger, Kara M Anasti, Robert Parks, Shelley Stewart, Cindy Bowman, Shi-Mao Xia, Ruijun Zhang, Xiaoying Shen, Richard M Scearce, Gilad Ofek, Yongping Yang, Peter D Kwong, Sampa Santra, Hua-Xin Liao, Georgia Tomaras, Norman L Letvin, Bing Chen, S Munir Alam, Barton F Haynes
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27824 (2011)
A component to the problem of inducing broad neutralizing HIV-1 gp41 membrane proximal external region (MPER) antibodies is the need to focus the antibody response to the transiently exposed MPER pre-hairpin intermediate neutralization epitope. Here
Externí odkaz:
https://doaj.org/article/d801a98ba7d142af95ee9b07aa0ca372
Autor:
Kelly E. Seaton, Rachel L. Spreng, Milite Abraha, Matthew Reichartz, Michelle Rojas, Frederick Feely, Richard H. C. Huntwork, Sheetij Dutta, Sarah V. Mudrak, S. Munir Alam, Scott Gregory, Erik Jongert, Margherita Coccia, Fernando Ulloa-Montoya, Ulrike Wille-Reece, Georgia D. Tomaras, S. Moses Dennison
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract RTS,S/AS01 is an advanced pre-erythrocytic malaria vaccine candidate with demonstrated vaccine efficacy up to 86.7% in controlled human malaria infection (CHMI) studies; however, reproducible immune correlates of protection (CoP) are elusive
Externí odkaz:
https://doaj.org/article/0219a60f06354a4495a0f6088c161287
Autor:
Merricka C. Livingstone, Alexis A. Bitzer, Alish Giri, Kun Luo, Rajeshwer S. Sankhala, Misook Choe, Xiaoyan Zou, S. Moses Dennison, Yuanzhang Li, William Washington, Viseth Ngauy, Georgia D. Tomaras, M. Gordon Joyce, Adrian H. Batchelor, Sheetij Dutta
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Plasmodium falciparum malaria contributes to a significant global disease burden. Circumsporozoite protein (CSP), the most abundant sporozoite stage antigen, is a prime vaccine candidate. Inhibitory monoclonal antibodies (mAbs) against CSP m
Externí odkaz:
https://doaj.org/article/f735407d93c347bfbd54ca0405a5bab5
Autor:
Tinashe E. Nyanhete, Robert J. Edwards, Celia C. LaBranche, Katayoun Mansouri, Amanda Eaton, S. Moses Dennison, Kevin O. Saunders, Derrick Goodman, Katarzyna Janowska, Rachel L. Spreng, Lu Zhang, Sarah V. Mudrak, Thomas J. Hope, Bhavna Hora, Todd Bradley, Ivelin S. Georgiev, David C. Montefiori, Priyamvada Acharya, Georgia D. Tomaras
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Broadly neutralizing antibodies (bNAbs), known to mediate immune control of HIV-1 infection, only develop in a small subset of HIV-1 infected individuals. Despite being traditionally associated with patients with high viral loads, bNAbs have also bee
Externí odkaz:
https://doaj.org/article/4c61ef5241d443e0b0ae4ef0bd8e6785
Autor:
Lindsay C. Dahora, Celina Jin, Rachel L. Spreng, Frederick Feely, Ryan Mathura, Kelly E. Seaton, Lu Zhang, Jennifer Hill, Elizabeth Jones, S. Munir Alam, S. Moses Dennison, Andrew J. Pollard, Georgia D. Tomaras
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Vaccination against Salmonella Typhi using the Vi capsular polysaccharide, a T-cell independent antigen, can protect from the development of typhoid fever. This implies that antibodies to Vi alone can protect in the absence of a T cell-mediated immun
Externí odkaz:
https://doaj.org/article/e8fec64964ec415e8b5d83f1cb315fc8
Autor:
Kan Li, Michael Dodds, Rachel L. Spreng, Milite Abraha, Richard H. C. Huntwork, Lindsay C. Dahora, Tinashe Nyanhete, Sheetij Dutta, Ulrike Wille-Reece, Erik Jongert, Katie J. Ewer, Adrian V. S. Hill, Celina Jin, Jennifer Hill, Andrew J. Pollard, S. Munir Alam, Georgia D. Tomaras, S. Moses Dennison
Publikováno v:
Frontiers in Immunology. 14
Diversity in specificity of polyclonal antibody (pAb) responses is extensively investigated in vaccine efficacy or immunological evaluations, but the heterogeneity in antibody avidity is rarely probed as convenient tools are lacking. Here we have dev