Zobrazeno 1 - 10
of 496
pro vyhledávání: '"S Mineev"'
Autor:
Yulia A. Bogdanova, Ilya D. Solovyev, Nadezhda S. Baleeva, Ivan N. Myasnyanko, Anastasia A. Gorshkova, Dmitriy A. Gorbachev, Aidar R. Gilvanov, Sergey A. Goncharuk, Marina V. Goncharuk, Konstantin S. Mineev, Alexander S. Arseniev, Alexey M. Bogdanov, Alexander P. Savitsky, Mikhail S. Baranov
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract In this paper, we propose a fluorescence-lifetime imaging microscopy (FLIM) multiplexing system based on the fluorogen-activating protein FAST. This genetically encoded fluorescent labeling platform employs FAST mutants that activate the sam
Externí odkaz:
https://doaj.org/article/764e7772d88c4d09a2b7a1e5753e170f
Autor:
Vladislav A Lushpa, Marina V Goncharuk, Irina A Talyzina, Alexander S Arseniev, Eduard V Bocharov, Konstantin S Mineev, Sergey A Goncharuk
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304997 (2024)
Toll-like receptors (TLRs) are key players in the innate immune system. Despite the great efforts in TLR structural biology, today we know the spatial structures of only four human TLR intracellular TIR domains. All of them belong to one of five subf
Externí odkaz:
https://doaj.org/article/9761a2e62c224787ad9499a872968cd1
Autor:
Fedor D. Kornilov, Yury B. Slonimskiy, Daria A. Lunegova, Nikita A. Egorkin, Anna G. Savitskaya, Sergey Yu. Kleymenov, Eugene G. Maksimov, Sergey A. Goncharuk, Konstantin S. Mineev, Nikolai N. Sluchanko
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Fasciclins (FAS1) are ancient adhesion protein domains with no common small ligand binding reported. A unique microalgal FAS1-containing astaxanthin (AXT)-binding protein (AstaP) binds a broad repertoire of carotenoids by a largely unknown m
Externí odkaz:
https://doaj.org/article/78b6c2636a5a4b1aa2163e97ab3973a8
Autor:
F. D. Kornilov, A. V. Shabalkina, Cong Lin, P. E. Volynsky, E. F. Kot, A. L. Kayushin, V. A. Lushpa, M. V. Goncharuk, A. S. Arseniev, S. A. Goncharuk, Xiaohui Wang, K. S. Mineev
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Toll-like receptors (TLRs) play a key role in the innate immune system. Here, Kornilov et al. resolve the 3D structures of the membrane-associated parts of four TLRs to reveal properties of the juxta-membrane domain.
Externí odkaz:
https://doaj.org/article/baf24e9ec2e8437598a63374214adbcb
Autor:
Nadezhda S. Baleeva, Yulia A. Bogdanova, Marina V. Goncharuk, Anatolii I. Sokolov, Ivan N. Myasnyanko, Vadim S. Kublitski, Alexander Yu. Smirnov, Aidar R. Gilvanov, Sergey A. Goncharuk, Konstantin S. Mineev, Mikhail S. Baranov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 3054 (2024)
NanoFAST is the smallest fluorogen-activating protein, consisting of only 98 amino acids, used as a genetically encoded fluorescent tag. Previously, only a single fluorogen with an orange color was revealed for this protein. In the present paper, usi
Externí odkaz:
https://doaj.org/article/6a2989e3ea8648639e42f26ae0dd5a45
Autor:
Marina V. Goncharuk, Nadezhda S. Baleeva, Dmitry E. Nolde, Alexey S. Gavrikov, Alexey V. Mishin, Alexander S. Mishin, Andrey Y. Sosorev, Alexander S. Arseniev, Sergey A. Goncharuk, Valentin I. Borshchevskiy, Roman G. Efremov, Konstantin S. Mineev, Mikhail S. Baranov
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Structural analyses guide the rational design of mutant fluorogen-activating proteins with enhanced fluorescence.
Externí odkaz:
https://doaj.org/article/9f5e4001803e45c99f3b5822fd1097f3
Facade-Based Bicelles as a New Tool for Production of Active Membrane Proteins in a Cell-Free System
Autor:
Marina V. Goncharuk, Ekaterina V. Vasileva, Egor A. Ananiev, Andrey Y. Gorokhovatsky, Eduard V. Bocharov, Konstantin S. Mineev, Sergey A. Goncharuk
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14864 (2023)
Integral membrane proteins are important components of a cell. Their structural and functional studies require production of milligram amounts of proteins, which nowadays is not a routine process. Cell-free protein synthesis is a prospective approach
Externí odkaz:
https://doaj.org/article/3b4d61702c3c4572a769e4cf5e4a5e90
Autor:
Ekaterina N. Grafskaia, Elizaveta R. Pavlova, Ivan A. Latsis, Maja V. Malakhova, Dmitrii V. Ivchenkov, Pavel V. Bashkirov, Erik F. Kot, Konstantin S. Mineev, Alexander S. Arseniev, Dmitry V. Klinov, Vassili N. Lazarev
Publikováno v:
Materials & Design, Vol 224, Iss , Pp 111364- (2022)
The number of infections caused by antibiotic-resistant pathogens is increasing alarmingly every year and will continue to grow. Antimicrobial peptides (AMPs) are considered new therapeutic agents for the effective combat against infectious diseases.
Externí odkaz:
https://doaj.org/article/173efa149e7440e38205a7555417109a
Autor:
Alexey I. Kuzmenkov, Steve Peigneur, Joshua A. Nasburg, Konstantin S. Mineev, Maxim V. Nikolaev, Ernesto Lopes Pinheiro-Junior, Alexander S. Arseniev, Heike Wulff, Jan Tytgat, Alexander A. Vassilevski
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Apamin is often cited as one of the few substances selectively acting on small-conductance Ca2+-activated potassium channels (KCa2). However, published pharmacological and structural data remain controversial. Here, we investigated the molecular phar
Externí odkaz:
https://doaj.org/article/03250e942dc5484ca71aad07a5e99041
Autor:
Vladislav A. Lushpa, Marina V. Goncharuk, Cong Lin, Arthur O. Zalevsky, Irina A. Talyzina, Aleksandra P. Luginina, Daniil D. Vakhrameev, Mikhail B. Shevtsov, Sergey A. Goncharuk, Alexander S. Arseniev, Valentin I. Borshchevskiy, Xiaohui Wang, Konstantin S. Mineev
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Lushpa et al report the structure and dynamics of the TLR1 toll-interleukin like (TIR) cytoplasmic domain in both crystal and solution. They demonstrate that the TLR1 TIR domain is capable of specific binding of Zn with nanomolar affinity, which appe
Externí odkaz:
https://doaj.org/article/ba1903b9028f4b788d2c7b76bc761832