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The Effects of a Perindopril-Based Regimen in Relation to Statin Use on the Outcomes of Patients with Vascular Disease
Autor: S. P. Radhoe, E. Boersma, M. Bertrand, W. Remme, R. Ferrari, K. Fox, S. MacMahon, J. Chalmers, M. L. Simoons, J. J. Brugts
Publikováno v: Cardiovascular Drugs and Therapy. Kluwer Academic
Purpose To study the effects of a perindopril-based regimen on cardiovascular (CV) outcomes in patients with vascular disease in relation to background statin therapy. Methods A pooled analysis of the randomized ADVANCE, EUROPA, and PROGRESS trials w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2836c6fcefb1ad82bb84d9ad6b099b7f
https://doi.org/10.1007/s10557-022-07384-2
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Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis
Autor: Milad Nazarzadeh, Zeinab Bidel, Dexter Canoy, Emma Copland, Derrick A Bennett, Abbas Dehghan, George Davey Smith, Rury R Holman, Mark Woodward, Ajay Gupta, Amanda I Adler, Malgorzata Wamil, Naveed Sattar, William C Cushman, Richard J McManus, Koon Teo, Barry R Davis, John Chalmers, Carl J Pepine, Kazem Rahimi, L Agodoa, A Algra, F W Asselbergs, N Beckett, E Berge, H Black, F P J Brouwers, M Brown, C J Bulpitt, B Byington, J Cutler, R B Devereaux, J Dwyer, R Estacio, R Fagard, K Fox, T Fukui, Y Imai, M Ishii, S Julius, Y Kanno, S E Kjeldsen, J Kostis, K Kuramoto, J Lanke, E Lewis, J Lewis, M Lievre, L H Lindholm, S Lueders, S MacMahon, G Mancia, M Matsuzaki, M H Mehlum, S Nissen, H Ogawa, T Ogihara, T Ohkubo, C Palmer, A Patel, M Pfeffer, N R Poulter, H Rakugi, G Reboldi, C Reid, G Remuzzi, P Ruggenenti, T Saruta, J Schrader, R Schrier, P Sever, P Sleight, J A Staessen, H Suzuki, L Thijs, K Ueshima, S Umemoto, W H van Gilst, P Verdecchia, K Wachtell, P Whelton, L Wing, Y Yui, S Yusuf, A Zanchetti, Z Y Zhang, C Anderson, C Baigent, BM Brenner, R Collins, D de Zeeuw, J Lubsen, E Malacco, B Neal, V Perkovic, B Pitt, A Rodgers, P Rothwell, G Salimi-Khorshidi, J Sundström, F Turnbull, G Viberti, J Wang
Publikováno v: Nazarzadeh, M, Bidel, Z, Canoy, D, Copland, E, Bennett, D A, Dehghan, A, Davey Smith, G, Holman, R R, Woodward, M, Gupta, A, Adler, A I, Wamil, M, Sattar, N, Cushman, W C, McManus, R J, Koon, T, Davis, B R, Chalmers, J, Pepine, C J & Rahimi, K 2022, ' Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes : an individual participant-level data meta-analysis ', Lancet Diabetes and Endocrinology, vol. 10, no. 9, pp. 645-654 . https://doi.org/10.1016/S2213-8587(22)00172-3
Background Controversy exists as to whether the threshold for blood pressure-lowering treatment should differ between people with and without type 2 diabetes. We aimed to investigate the effects of blood pressure-lowering treatment on the risk of maj
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44422d6b20717ea24c63a10d59c54203
https://pubmed.ncbi.nlm.nih.gov/36427521
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Quantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants
Autor: Lucy Loong, Cankut Cubuk, Subin Choi, Sophie Allen, Beth Torr, Alice Garrett, Chey Loveday, Miranda Durkie, Alison Callaway, George J. Burghel, James Drummond, Rachel Robinson, Ian R. Berry, Andrew Wallace, Diana M. Eccles, Marc Tischkowitz, Sian Ellard, James S. Ware, Helen Hanson, Clare Turnbull, S. Samant, A. Lucassen, A. Znaczko, A. Shaw, A. Ansari, A. Kumar, A. Donaldson, A. Murray, A. Ross, A. Taylor-Beadling, A. Taylor, A. Innes, A. Brady, A. Kulkarni, A.-C. Hogg, A. Ramsay Bowden, A. Hadonou, B. Coad, B. McIldowie, B. Speight, B. DeSouza, B. Mullaney, C. McKenna, C. Brewer, C. Olimpio, C. Clabby, C. Crosby, C. Jenkins, C. Armstrong, C. Bowles, C. Brooks, C. Byrne, C. Maurer, D. Baralle, D. Chubb, D. Stobo, D. Moore, D. O'Sullivan, D. Donnelly, D. Randhawa, D. Halliday, E. Atkinson, E. Baple, E. Rauter, E. Johnston, E. Woodward, E. Maher, E. Sofianopoulou, E. Petrides, F. Lalloo, F. McRonald, F. Pelz, I. Frayling, G. Evans, G. Corbett, G. Rea, H. Clouston, H. Powell, H. Williamson, H. Carley, H.J.W. Thomas, I. Tomlinson, J. Cook, J. Hoyle, J. Tellez, J. Whitworth, J. Williams, J. Murray, J. Campbell, J. Tolmie, J. Field, J. Mason, J. Burn, J. Bruty, J. Callaway, J. Grant, J. Del Rey Jimenez, J. Pagan, J. VanCampen, J. Barwell, K. Monahan, K. Tatton-Brown, K.-R. Ong, K. Murphy, K. Andrews, K. Mokretar, K. Cadoo, K. Smith, K. Baker, K. Brown, K. Reay, K. McKay Bounford, K. Bradshaw, K. Russell, K. Stone, K. Snape, L. Crookes, L. Reed, L. Taggart, L. Yarram, L. Cobbold, L. Walker, L. Hawkes, L. Busby, L. Izatt, L. Kiely, L. Hughes, L. Side, L. Sarkies, K.-L. Greenhalgh, M. Shanmugasundaram, M. Duff, M. Bartlett, M. Watson, M. Owens, M. Bradford, M. Huxley, M. Slean, M. Ryten, M. Smith, M. Ahmed, N. Roberts, C. O'Brien, O. Middleton, P. Tarpey, P. Logan, P. Dean, P. May, P. Brace, R. Tredwell, R. Harrison, R. Hart, R. Kirk, R. Martin, R. Nyanhete, R. Wright, R. Davidson, R. Cleaver, S. Talukdar, S. Butler, J. Sampson, S. Ribeiro, S. Dell, S. Mackenzie, S. Hegarty, S. Albaba, S. McKee, S. Palmer-Smith, S. Heggarty, S. MacParland, S. Greville-Heygate, S. Daniels, S. Prapa, S. Abbs, S. Tennant, S. Hardy, S. MacMahon, T. McVeigh, T. Foo, T. Bedenham, T. Cranston, T. McDevitt, V. Clowes, V. Tripathi, V. McConnell, N. Woodwaer, Y. Wallis, Z. Kemp, G. Mullan, L. Pierson, L. Rainey, C. Joyce, A. Timbs, A.-M. Reuther, B. Frugtniet, C. Husher, C. Lawn, C. Corbett, D. Nocera-Jijon, D. Reay, E. Cross, F. Ryan, H. Lindsay, J. Oliver, J. Dring, J. Spiers, J. Harper, K. Ciucias, L. Connolly, M. Tsang, R. Brown, S. Shepherd, S. Begum, T. Tadiso, T. Linton-Willoughby, H. Heppell, K. Sahan, L. Worrillow, Z. Allen, M. Barlett, C. Watt, M. Hegarty
Publikováno v: Loong, L, Cubuk, C, Choi, S, Allen, S, Torr, B, Garrett, A, Loveday, C, Durkie, M, Callaway, A, Burghel, GJ, Drummond, J, Robinson, R, Berry, IR, Wallace, A & CanVIG-UK 2021, ' Quantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants. ', Genetics in medicine : official journal of the American College of Medical Genetics, vol. 24, no. 3, pp. 552-563 . https://doi.org/10.1016/j.gim.2021.11.011
Purpose: Conditions and thresholds applied for evidence weighting of within-codon concordance (PM5) for pathogenicity vary widely between laboratories and expert groups. Because of the sparseness of available clinical classifications, there is little
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a638418e559b935daf78b3ef4e1f05a
http://hdl.handle.net/10044/1/95227
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