Zobrazeno 1 - 10
of 13
pro vyhledávání: '"S M de Toledo"'
Autor:
S. M. de Toledo, Perumal Venkatachalam, A. B. Carter, Douglas R. Spitz, Linda A. Tephly, Edouard I. Azzam, John B. Little, B N Pandey
Publikováno v:
Oncogene. 27:20-31
Mechanisms underlying the role of reactive oxygen species (ROS) generated by flavin-containing oxidases in regulating cell cycle progression were examined in human and rodent fibroblasts. Incubation of confluent cell cultures with nontoxic/nonclastog
Publikováno v:
International Journal of Radiation Biology. 67:135-143
One way to study the effect of radiation on gene expression is to monitor changes in the levels of specific messenger RNAs. We describe the use of reverse transcription-polymerase chain reaction (RT-PCR) analysis, a faster and more sensitive procedur
Publikováno v:
Journal de Chimie Physique. 91:931-936
Les doses faibles et les debits de dose faibles de rayonnement ionisant augmentent la vitesse de reparation de l'ADN des fibroblastes de peau humaine et protegent les cellules contre la formation de micronoyaux par le rayonneraient. Des expositions c
Publikováno v:
The Journal of Immunology. 146:2201-2206
Hypophysectomy of Fischer 344 rats of both sexes led to a rapid involution of the thymus and spleen which was associated with a profound decrease in spontaneous DNA synthesis in these organs. The proportion of B lymphocytes in the spleen, of T cells
Publikováno v:
Radiation protection dosimetry. 99(1-4)
Biological effects were examined in confluent cultures of fibroblasts and epithelial cells exposed to very low mean doses of alpha radiation, doses by which only 1-2% of the cells were actually traversed by an alpha particle. Enhanced frequencies of
Publikováno v:
Cancer research. 60(10)
The effects of exposure to high and very low fluence alpha-particles on the G1 checkpoint were investigated in human diploid fibroblasts irradiated and released from density-inhibited confluent cultures by the use of the cumulative labeling index met
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 9(11)
Induced cell cycle delays were among the first described cellular responses to ionizing radiation (IR). To understand the sensitivity and the molecular events involved in the response to low doses of IR and to examine the role of p53 and its downstre
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(11)
The mammalian cellular response to ionizing radiation results in delays in progression through the cell cycle at several checkpoints and includes alterations in the activity of cyclin-dependent kinases. The product of the CDC2 gene is a key kinase in
Publikováno v:
Stress-Inducible Processes in Higher Eukaryotic Cells ISBN: 9781489900715
The concept of an ionizing radiation-induced increase in resistance against the effects of a subsequent exposure is an accepted and reasonably well-understood process in both prokaryotes (Walker, 1984, 1985) and nonmammalian eukaryotes (Calkins, 1967
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffee994761cfe5f9720568f51960bb0d
https://doi.org/10.1007/978-1-4899-0069-2_9
https://doi.org/10.1007/978-1-4899-0069-2_9
Publikováno v:
Radiation research. 146(4)
We have previously shown that chronic exposure of plateau-phase C3H 10 T1/2 cells to (60)Co gamma radiation at doses as low as 10 cGy protected the cells against neoplastic transformation by a subsequent large acute radiation exposure. We have also s