Zobrazeno 1 - 10
of 26
pro vyhledávání: '"S M Sundaram"'
Publikováno v:
ARKIVOC, Vol 2007, Iss 5, Pp 231-242 (2007)
Externí odkaz:
https://doaj.org/article/1224077d8533443daeaefbad117f905b
Publikováno v:
Nuclear medicine and biology.
Introduction To allow quantitative assessment of therapeutic efficacy for therapeutic interventions (either approved or undergoing FDA approvals) for either inhibiting or reducing development of Aβ pathophysiology in vivo, 18F-labelled tracers, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5f542617dea5b17dde0b39b8f791e3
https://pubmed.ncbi.nlm.nih.gov/31891882
https://pubmed.ncbi.nlm.nih.gov/31891882
Autor:
Monica Sharma, G. S. M. Sundaram, Junsang Cho, Scott E. Harpstrite, Daniel Kaganov, Vijay Sharma
Publikováno v:
Journal of Inorganic Biochemistry. 159:159-164
Radiolabeled metalloprobes offer sensitive tools for evaluating quantitative accumulation of chemical entities within pooled cell populations. Although beneficial in translational nuclear imaging, this method precludes interrogation of effects result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4338a75042d85ef5feb1623fb9f70bbc
https://doi.org/10.1016/j.jinorgbio.2016.02.022
https://doi.org/10.1016/j.jinorgbio.2016.02.022
Live-cell fluorescence imaging: assessment of thioflavin T uptake in human epidermal carcinoma cells
Thioflavin T (ThT), a positively charged heterocyclic small molecule, is a widely used fluorescent marker of amyloid pathophysiology to confirm the cause of death in post mortem brain tissue of Alzheimer's disease (AD) patients. Literature precedents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7912d0aca8ec6b6738597f8b5820a125
https://europepmc.org/articles/PMC6072315/
https://europepmc.org/articles/PMC6072315/
Autor:
Nigam P. Rath, Kanchan Garai, Ping Yan, G. S. M. Sundaram, Nigel J. Cairns, John R. Cirrito, Jin-Moo Lee, Vijay Sharma
Publikováno v:
Organic Letters
Emerging paradigms mandate discovery of imaging agents for diagnosing Alzheimer's disease (AD) prior to appearance of clinical symptoms. To accomplish this objective, a novel heterocyclic molecule (4) was synthesized and validated as Aβ targeted pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7d61c3015d14b80f53e9952fd45234
https://doi.org/10.1021/ol501264q
https://doi.org/10.1021/ol501264q
Autor:
Nigel J. Cairns, Richard Laforest, John R. Cirrito, Jin-Moo Lee, Paul T. Kotzbauer, Nigam P. Rath, Vivek Sharma, G. S. M. Sundaram, Ping Yan, Dhruva Dhavale, Julie L. Prior
Publikováno v:
Scientific Reports
Fluselenamyl (5), a novel planar benzoselenazole shows traits desirable of enabling noninvasive imaging of Aβ pathophysiology in vivo; labeling of both diffuse (an earlier manifestation of neuritic plaques) and fibrillar plaques in Alzheimer’s dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53678557a10b57ae4d74b5e76234cd57
https://doi.org/10.1038/srep35636
https://doi.org/10.1038/srep35636
Autor:
Heike Heuer, F. W. Pfrieger, Sigrun Nagel, S. M. Sundaram, Ronny Haenold, Anita Boelen, E. M. de Vries, Ellen A. Fliers
Publikováno v:
Endocrinology
Endocrinology, Oxford University Press, 2016, 157 (7), pp.2947-2956. ⟨10.1210/en.2016-1027⟩
Endocrinology, 157(7), 2947-2956. The Endocrine Society
Endocrinology, Oxford University Press, 2016, 157 (7), pp.2947-2956. ⟨10.1210/en.2016-1027⟩
Endocrinology, 157(7), 2947-2956. The Endocrine Society
A large proportion of critically ill patients have alterations in the hypothalamus-pituitary-thyroid (HPT) axis, collectively known as the nonthyroidal illness syndrome. Nonthyroidal illness syndrome is characterized by low serum thyroid hormone (TH)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd48b8709a1e8224ab1fc2af3f8c930a
https://hal.archives-ouvertes.fr/hal-02882613
https://hal.archives-ouvertes.fr/hal-02882613
Autor:
Eric Michael Tippmann, Anthony S. Evans, John P. Toscano, G. S. M. Sundaram, Jörg Sassmannshausen
Publikováno v:
Organic Letters. 12:4616-4619
A chloromethylhydroxamiccarbene was generated photochemically in an attempt to form an intramolecularly stabilized carbene. A rapidly formed intermediate at 1645 cm(-1) decayed with an observed rate of 1.99 × 10(6) s(-1). Other intermediates were al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579cf85714efd27f4727c85f028b350e
https://doi.org/10.1021/ol101946u
https://doi.org/10.1021/ol101946u
Publikováno v:
Amino Acids. 39:1381-1384
The ability to incorporate non-canonical amino acids into proteins by genetic or chemical methods allows one to introduce novel chemical properties into a protein at a defined residue. Such a residue may then be modified using common organic transfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4173a1c47d13dbff0e92403d4a9ba83
https://doi.org/10.1007/s00726-010-0594-3
https://doi.org/10.1007/s00726-010-0594-3
Publikováno v:
Tetrahedron Letters. 50:366-369
An efficient one-pot, three-component synthesis of novel 2-substituted-5-aryl-1-oxo-3-thioxo-1,2,3,5,11,11a-hexahydro-6H-imidazo-[1,5-b]-β-carbolines employing 1-aryl-1,2,3,4-tetrahydro-β-carboline-3-carboxylates, primary amines (or amino acid este
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e217115ecbef200e8a0b8979ea8c93b
https://doi.org/10.1016/j.tetlet.2008.11.008
https://doi.org/10.1016/j.tetlet.2008.11.008