Výsledky vyhledávání - "S M Prescott"

P-selectin regulates platelet-activating factor synthesis and phagocytosis by monocytes

Autor: M R Elstad, T R La Pine, F S Cowley, R P McEver, T M McIntyre, S M Prescott, G A Zimmerman

Publikováno v: The Journal of Immunology. 155:2109-2122

Adhesion molecules on endothelial cells or platelets may regulate localization and activation of leukocytes at sites of tissue injury, infection, or thrombosis. In these studies, we found that human peripheral blood monocytes adhered specifically to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1db9f47e2a16f088f0a609f3331bbade
https://doi.org/10.4049/jimmunol.155.4.2109

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CD11b/CD18 integrin and a beta-glucan receptor act in concert to induce the synthesis of platelet-activating factor by monocytes

Autor: M R Elstad, C J Parker, F S Cowley, L A Wilcox, T M McIntyre, S M Prescott, G A Zimmerman

Publikováno v: The Journal of Immunology. 152:220-230

We determined the mechanism by which opsonized zymosan particles, which are derived from yeast and composed of carbohydrate polymers, stimulate platelet-activating factor (PAF) synthesis by monocytes. A role for CD11b/CD18 was demonstrated because an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f490a31a45fd9a45939ee3704c5aeaa
https://doi.org/10.4049/jimmunol.152.1.220

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Classification of venous thromboembolism (VTE). The clot is hot: inflammation, myeloid leukocytes, and venous thromboembolism

Autor: S M, Prescott, A S, Weyrich, G A, Zimmerman

Publikováno v: Journal of thrombosis and haemostasis : JTH. 3(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2451c71001ff22046d43a715e86f9692
https://pubmed.ncbi.nlm.nih.gov/16241957

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Fatty acid CoA ligase 4 is up-regulated in colon adenocarcinoma

Autor: Y, Cao, K B, Dave, T P, Doan, S M, Prescott

Publikováno v: Cancer research. 61(23)

Arachidonic acid metabolism plays an important role in colon carcinogenesis. Cyclooxygenase-2 (COX-2), which catalyzes the rate-limiting step in the synthesis of prostaglandins from arachidonic acids, is known to be up-regulated in colon cancer, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c3efe2f4c332199906b9bcf1656984f
https://pubmed.ncbi.nlm.nih.gov/11731423

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Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids

Autor: G K, Marathe, A R, Silva, H C, de Castro Faria Neto, L W, Tjoelker, S M, Prescott, G A, Zimmerman, T M, McIntyre

Publikováno v: Journal of lipid research. 42(9)

Lysophosphatidylcholine is an abundant component of plasma and oxidized LDL that displays several biological activities, some of which may occur through the platelet-activating factor (PAF) receptor. We find that commercial lysophosphatidylcholine, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26fe12dd1ac03af91ed297e9a089e053
https://pubmed.ncbi.nlm.nih.gov/11518762

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Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions

Autor: A, Hogan, L, Shepherd, J, Chabot, S, Quenneville, S M, Prescott, M K, Topham, S H, Gee

Publikováno v: The Journal of biological chemistry. 276(28)

Syntrophins are modular adapter proteins that link ion channels and signaling proteins to dystrophin and its homologues. A yeast two-hybrid screen of a human brain cDNA library using the PDZ domain of gamma 1- syntrophin, a recently identified brain-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fa3c9e5658a2b959875360abf5775162
https://pubmed.ncbi.nlm.nih.gov/11352924

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Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver

Autor: G K, Marathe, K A, Harrison, L J, Roberts, J D, Morrow, R C, Murphy, L W, Tjoelker, S M, Prescott, G A, Zimmerman, T M, McIntyre

Publikováno v: Journal of lipid research. 42(4)

Unmitigated oxidative stress is deleterious, as epitomized by CCl4 intoxication. In this well-characterized model of free radical-initiated damage, liver metabolism of CCl4 to CCl3. causes lipid peroxidation, F-ring isoprostane formation, and patholo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0df020751f3c709082d2a3799a112974
https://pubmed.ncbi.nlm.nih.gov/11290831

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Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region

Autor: D A, Dixon, C D, Kaplan, T M, McIntyre, G A, Zimmerman, S M, Prescott

Publikováno v: The Journal of biological chemistry. 275(16)

The cyclooxygenase (COX)-2 enzyme is responsible for increased prostaglandin formation in inflammatory states and is the major target of nonsteroidal anti-inflammatory drugs. Normally COX-2 expression is tightly regulated, however, constitutive overe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b8a713c08e0772e63cb5a92b50fa2fa
https://pubmed.ncbi.nlm.nih.gov/10766797

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