Výsledky vyhledávání - "S M O, Hourani"

Increased desensitization of dopamine D₂ receptor-mediated response in the ventral tegmental area in the absence of adenosine A(2A) receptors

Autor: R, Al-Hasani, J D, Foster, A, Metaxas, C, Ledent, S M O, Hourani, I, Kitchen, Y, Chen

Publikováno v: Neuroscience. 190

G-protein coupled receptors interact to provide additional regulatory mechanisms for neurotransmitter signaling. Adenosine A(2A) receptors are expressed at a high density in striatal neurons, where they closely interact with dopamine D₂ receptors a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0077d60736bce880ebfbf0f30e2f3cf0
https://pubmed.ncbi.nlm.nih.gov/21669258

Zobrazit plný text záznamu

Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and pain

Autor: S, Ferré, I, Diamond, S R, Goldberg, L, Yao, S M O, Hourani, Z L, Huang, Y, Urade, I, Kitchen

Publikováno v: Progress in neurobiology. 83(5)

Adenosine A2A receptors localized in the dorsal striatum are considered as a new target for the development of antiparkinsonian drugs. Co-administration of A2A receptor antagonists has shown a significant improvement of the effects of L-DOPA. The pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7bf6d4f0c024c0ca7a32603ff764884c
https://pubmed.ncbi.nlm.nih.gov/17532111

Zobrazit plný text záznamu

Structure Activity Relationships for Adenine Nucleotide Receptors on Mast Cells, Human Platelets, and Smooth Muscle

Autor: N. J. Cusack, S. M. O. Hourani

Publikováno v: Purines in Cellular Signaling ISBN: 9781461279969

Extracellular adenine nucleotides, adenosine 5′-monophosphate (AMP), adenosine 5′-diphosphate (ADP) and adenosine 5′-triphosphate (ATP) are active on mast cells, platelets and smooth muscle. These P2 purinoceptor-mediated actions have very diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3a474ff6912f6a4705a991b118fd21f
https://doi.org/10.1007/978-1-4612-3400-5_37

Zobrazit plný text záznamu

Adenosine 5’-O-(2-Thiodiphosphate) (ADP-β-S) Is A Partial Agonist At The ADP Receptor Of Human Platelets

Autor: N J Cusack, S M O Hourani

Publikováno v: Oral Presentations.

ADP induces human platelet aggregation and inhibits the stimulation of platelet adenylate cyclase by prostaglandin E1 (PGE1), but analogues of ADP in which the diphosphate group is modified retain only weak aggregating activity. However, ADP-β-S, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d63d8815cd4acc3f6c920ee2f6ac777
https://doi.org/10.1055/s-0038-1652016

Zobrazit plný text záznamu

5'-N-Ethylcarboxamidoadenosine (NECA) Is A Potent, Stereospecific Inhibitor Of Human Platelet Aggregation

Autor: N J Cusack, S M O Hourani

Publikováno v: Oral Presentations.

Adenosine is a vasodilator, and also inhibits platelet aggregation apparently by acting at an external membrane receptor to increase levels of platelet cyclic AMP. Certain analogues of adenosine retain activity as vasodilators, and also inhibit plate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b3fd2b5d88f10b86c3b244f66c675ff
https://doi.org/10.1055/s-0038-1652403

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání