Zobrazeno 1 - 10
of 50
pro vyhledávání: '"S M Kirpekar"'
Publikováno v:
Neuroscience. 10:1455-1462
The experiments were designed to quantify pharmacologically the degree of participation of channels associated with the nicotinic cholinoceptor compared with voltage-sensitive channels during the evoked release of [3H]noradrenaline from prelabelled 3
Publikováno v:
The Journal of Physiology. 333:595-618
1. Noradrenaline release and radioligand binding studies were carried out in the cat hypogastric nerve ligated in vito 2 cm distal to the inferior mesenteric ganglion for different time periods, and in different effector organs.2. Large quantities of
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 287:205-212
The sympathetic nerves of the cat spleen were stimulated electrically (20 v, 1 msec, 7 sec) with increasing frequencies (1–30 Hz) during perfusion of the spleen with normal or low-calcium Krebs solution. Noradrenaline (NA) output per stimulus was m
Autor:
J. S. Gillespie, S. M. Kirpekar
Publikováno v:
The Journal of Physiology. 187:69-79
1. The histological localization of noradrenaline in the cat spleen has been studied with a fluorescence technique and, after infusing DL-[3H] noradrenaline, both by the fluorescence technique and by autoradiography. 2. In the normal cat spleen the s
Autor:
S. M. Kirpekar, J. J. Lewis
Publikováno v:
British Journal of Pharmacology and Chemotherapy. 15:175-180
The effects of reserpine, chlorpromazine and sodium salicylate on oxidative phosphorylation, stimulation of glutamic acid oxidation and adenosinetriphosphatase activity have been compared in vitro with those of 2,4-dinitrophenol using rat liver prepa
Autor:
S. M. Kirpekar, J. J. Lewis
Publikováno v:
Journal of Pharmacy and Pharmacology. 10:307-314
Many intermediates of carbohydrate, fat and protein metabolism give protection against the hydrallazine depression of acetylcholine, (-)-adrenaline, (-)-noradrenaline, histamine and 5-hydroxytryptamine-induced contractions of spirally cut strips of h
Autor:
J. J. Lewis, S. M. Kirpekar
Publikováno v:
Journal of Pharmacy and Pharmacology. 9:877-888
Hydrallazine and dihydrallazine cause adrenaline reversal and antagonise the pressor effects of noradrenaline on the cat blood pressure. Both hydrallazine and dihydrallazine antagonise vasoconstriction caused by adrenaline, noradrenaline, histamine,
Publikováno v:
The Journal of Physiology. 224:105-119
1. A spontaneous discharge of small potentials from smooth muscle cells of the guinea-pig seminal vesicle has been described. The mean amplitude, frequency and duration of the potentials were 0.9 mV, 12.2/min, and 92 msec, respectively. Occasionally,
Autor:
S. M. Kirpekar, A. R. Wakade
Publikováno v:
The Journal of Physiology. 194:609-626
1. Noradrenaline was infused intra-arterially at the constant rate of 0·51 μg/min for 22 min into the cat spleen perfused with Krebs saline, and the amount appearing in the perfusate was assayed either chemically or on the blood pressure of the pit
Autor:
S. M. Kirpekar, A. G. Garcia
Publikováno v:
The Journal of Physiology. 235:693-713
1. Spleen slices pre-incubated for different periods at 4° C in Krebs solution containing varying concentrations of calcium, up to 96 m M, lost their endogenous noradrenaline stores when reincubated in normal Krebs solution at 37° C for 2 hr. Rate