Zobrazeno 1 - 10
of 47
pro vyhledávání: '"S M Herrmann"'
Autor:
Agnieszka Olszanecka, Eva Brand, S-M Herrmann, Jan A. Staessen, Yu. P. Nikitin, Katarzyna Stolarz, Tatiana Kuznetsova, Kalina Kawecka-Jaszcz, A Ryabikov
Publikováno v:
Journal of Human Hypertension. 17:325-332
The 825T allele of the G-protein beta(3)-subunit is associated with increased intracellular signalling. Its association with hypertension is inconsistent. We, therefore, studied the C825T polymorphism in relation to ambulatory blood pressure as well
Autor:
Marcus Quinkler, Wolfgang Oelkers, Volker Bähr, S. Diederich, I Anagnostopoulos, C Bumke-Vogt, S M Herrmann
Publikováno v:
Journal of Endocrinology. 175:349-364
Due to high binding affinity of progesterone to the human mineralocorticoid receptor (hMR), progesterone competes with the natural ligand aldosterone. In order to analyse how homeostasis can be maintained by mineralocorticoid function of aldosterone
Autor:
Dzuy T. Nguyen, Eleanor F. Howland, S. M. Herrmann, C. A. Morse, Russell J. Bacquet, Jones Terence R, Ward W. Smith, Charlotte A. Bartlett, Stephanie Webber, K. M. Welsh, Cheryl Ann Janson, Kathardekar, M. R. Reddy, Carol L. J. Booth, H. Mazdiyasni, Lewis Kk, J. White, A. Johnston, J. Deal, Stephen E. Webber, David A. Matthews, Robert William Ward, Varney
Publikováno v:
Journal of Medicinal Chemistry. 40:677-683
Six new diphenyl sulfoxide and five new diphenyl sulfones were designed, synthesized, and tested for their inhibition of human and Escherichia coli thymidylate synthase (TS) and of the growth of cells in tissue culture. The best sulfoxide inhibitor o
Autor:
Jesus Ernesto Villafranca, Carol L. J. Booth, Charlotte A. Bartlett, Stephanie Webber, Cindy L. Palmer, C. A. Morse, Varney Michael D, Ellen W. Moomaw, Jones Terence R, S. M. Herrmann, Krzysztof Appelt, Kathleen K. Lewis, Katharine M. Welsh, Robert William Ward, Cheryl Ann Janson, Russell J. Bacquet, Eleanor F. Howland, Ward W. Smith, Stephen E. Webber, Vinit Kathardekar, David A. Matthews, Jennifer White, Marzoni Gifford P
Publikováno v:
Journal of Medicinal Chemistry. 39:904-917
To develop novel lipophilic thymidylate synthase (TS) inhibitors, the X-ray structure of Escherichia coli TS in ternary complex with FdUMP and the inhibitor 10-propargyl-5,8-dideazafolic acid (CB3717) was used as a basis for structure-based design. A
Autor:
Eleanor F. Howland, S. H. Reich, J. White, Varney Michael D, Marzoni Gifford P, S. M. Herrmann, C. A. Morse, Robert William Ward, Carol L. J. Booth, K. M. Welsh, Nguyen Dzuy Nguyen Dzuy, Charlotte A. Bartlett, Stephanie Webber
Publikováno v:
ChemInform. 24
Autor:
T. R. JONES, M. D. VARNEY, S. E. WEBBER, K. K. LEWIS, G. P. MARZONI, C. L. PALMER, V. KATHARDEKAR, K. M. WELSH, S. WEBBER, D. A. MATTHEWS, K. APPELT, W. W. SMITH, C. A. JANSON, J. E. VILLAFRANCA, R. J. BACQUET, E. F. HOWLAND, C. L. J. BOOTH, S. M. HERRMANN, R. W. WARD, J. WHITE, ET AL. ET AL.
Publikováno v:
ChemInform. 27
Autor:
K. K. Lewis, Varney Michael D, V. Kathardekar, Stephen E. Webber, W. W. Smith, J. Deal, K. M. Welsh, Eleanor F. Howland, A L A L Et Et, Cheryl Ann Janson, S. M. Herrmann, Robert William Ward, M. R. Reddy, Jones Terence R, H. Mazdiyasni, A. Johnston, Nguyen Dzuy Nguyen Dzuy, David A. Matthews, Carol L. J. Booth, R. J. Bacquet, J. M. White, Stephanie Webber
Publikováno v:
ChemInform. 28
Autor:
K, Appelt, R J, Bacquet, C A, Bartlett, C L, Booth, S T, Freer, M A, Fuhry, M R, Gehring, S M, Herrmann, E F, Howland, C A, Janson
Publikováno v:
Journal of Medicinal Chemistry. 34:1925-1934
Publikováno v:
Journal of Biological Chemistry. 265:16402-16411
A procedure is described for the purification from cultured mouse cells of two DNA polymerase "delta-like" enzymes, as defined by intrinsic 3'-exonuclease activity, inhibition by aphidicolin, and relative insensitivity to N2-(p-n-butylphenyl)-dGTP. O
Autor:
O, Poirier, C, Mao, C, Mallet, V, Nicaud, S M, Herrmann, A, Evans, J B, Ruidavets, D, Arveiler, G, Luc, L, Tiret, F, Soubrier, F, Cambien
Publikováno v:
European journal of clinical investigation. 29(4)
Our aim in the present study was to determine whether endothelial NO synthase gene (ecNOS) polymorphisms are associated with myocardial infarction (MI).Forty chromosomes from patients with MI were screened for polymorphisms of the ecNOS gene using po