Zobrazeno 1 - 10
of 35
pro vyhledávání: '"S M Freeman"'
Publikováno v:
Methods in molecular medicine. 35
Gene therapy is defined as the alteration of the genetic material of a cell with resultant benefit to a patient. Gene transfer has two broad categories: one in which a therapeutic gene is delivered to the cells with the aim of treating a disease; and
Publikováno v:
Journal of Virology. 65:6365-6370
Nonimmortalized mouse mammary epithelial cells expressing Escherichia coli beta-galactosidase from a murine amphotropic packaged retroviral vector were injected into the epithelium-divested mammary fat pads of syngeneic mice. Mammary glands formed fr
Autor:
S M, Freeman
Publikováno v:
Advances in experimental medicine and biology. 465
Autor:
S A, Rosenberg, R M, Blaese, M K, Brenner, A B, Deisseroth, F D, Ledley, M T, Lotze, J M, Wilson, G J, Nabel, K, Cornetta, J S, Economou, S M, Freeman, S R, Riddell, M, Brenner, E, Oldfield, B, Gansbacher, C, Dunbar, R E, Walker, F G, Schuening, J A, Roth, R G, Crystal, M J, Welsh, K, Culver, H E, Heslop, J, Simons, R W, Wilmott, R C, Boucher, H F, Siegler, J A, Barranger, S, Karlsson, D, Kohn, J E, Galpin, C, Raffel, C, Hesdorffer, J, Ilan, P, Cassileth, J, O'Shaughnessy, L E, Kun, T K, Das, F, Wong-Staal, R E, Sobol, R, Haubrich, M, Sznol, J, Rubin, E J, Sorcher, J, Rosenblatt, R, Walker, K, Brigham, N, Vogelzang, E, Hersh, S L, Eck
Publikováno v:
Human gene therapy. 11(6)
Publikováno v:
Archives of pathologylaboratory medicine. 123(4)
Low malignant potential tumors of the ovary are believed to behave in a manner intermediate to their benign and malignant counterparts. However, recent evidence suggests these lesions are in fact benign and better classified as proliferative. Based o
Publikováno v:
Hematology/oncology clinics of North America. 13(1)
Genetic abnormalities of cancer cells are complex and usually nonspecific. Genetic anomalies specific to ovarian cancer have not been reported. This article focuses on what molecular anomalies are known in ovarian cancer and describes the first trial
Publikováno v:
Advances in experimental medicine and biology. 451
Publikováno v:
International journal of cancer. 80(3)
Tumor cells genetically modified with the herpes simplex virus thymidine kinase (HSV-tk) gene in combination with ganciclovir (GCV) demonstrate a "bystander effect". Previous attempts to enhance the bystander tumor killing by combining cytokine genes
Autor:
P, Schwarzenberger, L, Harrison, A, Weinacker, A, Marrogi, P, Byrne, R, Ramesh, C, Theodossiou, R, Gaumer, W, Summer, S M, Freeman, J K, Kolls
Publikováno v:
Human gene therapy. 9(17)
Malignant mesothelioma is a tumor of the pleura for which there is no satisfactory treatment. It is almost universally fatal, regardless of the stage of the tumor at the time of diagnosis. Current treatment modalities include surgery, chemotherapy, a
Publikováno v:
The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society. 150(4)
The tumor suppressor gene, p53, is the most commonly mutated gene associated with cancer. Mutation of p53 plays a critical role in the multiple stages of carcinogenesis. The functional inactivation of p53 by missense mutations has been described in v