Zobrazeno 1 - 2
of 2
pro vyhledávání: '"S M, Wuerzberger"'
Autor:
T T, Huang, S M, Wuerzberger-Davis, B J, Seufzer, S D, Shumway, T, Kurama, D A, Boothman, S, Miyamoto
Publikováno v:
The Journal of biological chemistry. 275(13)
Activation of the transcription factor NF-kappaB by extracellular signals involves its release from the inhibitor protein IkappaBalpha in the cytoplasm and subsequent nuclear translocation. NF-kappaB can also be activated by the anticancer agent camp
Publikováno v:
Cancer research. 58(9)
Beta-lapachone (beta-lap) affects a number of enzymes in vitro, including type I topoisomerase (Topo I); however, its exact intracellular target(s) and mechanism of cell killing remain unknown. We compared the cytotoxic responses of MCF-7:WS8 (MCF-7)