Zobrazeno 1 - 10 of 10 pro vyhledávání: '"S M, Willems"'
1
Akademický článek
Optimising primary molecular profiling in non-small cell lung cancer.
Autor: R D Schouten, I Schouten, M M F Schuurbiers, V van der Noort, R A M Damhuis, E H F M van der Heijden, J A Burgers, N P Barlo, A S R van Lindert, K W Maas, J J G van den Brand, A A J Smit, J M W van Haarst, B van der Maat, E Schuuring, H Blaauwgeers, S M Willems, K Monkhorst, D van den Broek, M M van den Heuvel
Publikováno v: PLoS ONE, Vol 19, Iss 7, p e0290939 (2024)
IntroductionMolecular profiling of NSCLC is essential for optimising treatment decisions, but often incomplete. We assessed the efficacy of protocolised molecular profiling in the current standard-of-care (SoC) in a prospective observational study in
Externí odkaz: https://doaj.org/article/87e38726aa1c4be1b473231f9e459023
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2
Akademický článek
Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma
Autor: W. S. M. E. Theelen, O. Krijgsman, K. Monkhorst, T. Kuilman, D. D. G. C. Peters, S. Cornelissen, M. A. Ligtenberg, S. M. Willems, J. L. G. Blaauwgeers, C. J. M. van Noesel, D. S. Peeper, M. M. van den Heuvel, K. Schulze
Publikováno v: Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background The tumor immune microenvironment is a heterogeneous entity. Gene expression analysis allows us to perform comprehensive immunoprofiling and may assist in dissecting the different components of the immune infiltrate. As gene expre
Externí odkaz: https://doaj.org/article/debbea0e0b5047e685a2c5ef50af7bd0
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3
Additional file 2 of Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma
Autor: Theelen, W. S. M. E., O. Krijgsman, K. Monkhorst, T. Kuilman, D. D. G. C. Peters, S. Cornelissen, M. A. Ligtenberg, S. M. Willems, J. L. G. Blaauwgeers, C. J. M. Van Noesel, D. S. Peeper, M. M. Van Den Heuvel, K. Schulze
Additional file 2: Figure S1. A) Flowchart of samples for NanoString analysis. B) QC data NanoString: positive/negative controls and keratin expression. C) The 34-gene signature does not work on TCGA RNA-seq data: unmeasurable or low expression of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fc61c83c177e00f4611c106b59819b
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5
Additional file 4 of Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma
Autor: Theelen, W. S. M. E., O. Krijgsman, K. Monkhorst, T. Kuilman, D. D. G. C. Peters, S. Cornelissen, M. A. Ligtenberg, S. M. Willems, J. L. G. Blaauwgeers, C. J. M. Van Noesel, D. S. Peeper, M. M. Van Den Heuvel, K. Schulze
Additional file 4: Figure S2. Boxplots of the associations between the immune response genes and the 34-gene signature with PD-L1 expression on tumor cells (TC) and immune cells (IC) and CD8 infiltration in the tumor margin and in the tumor center.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b7c367c3dff752fc8da8a852cae6a3
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6
[Cutting through tumour in head and neck cancer: still a taboo?]
Autor: R, de Bree, S M, Willems, L M, Janssen, M W M, van den Brekel
Publikováno v: Nederlands tijdschrift voor geneeskunde. 161
When resecting head and neck tumours, the aim is mostly to strive for en bloc resection with sufficiently large tumour-free margins. If this is not possible, as is frequently the case with transoral laser microsurgery and endonasal endoscopic surgery
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::62bda75d7520f20610acd00cdd805a22
https://pubmed.ncbi.nlm.nih.gov/28854985
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7
p16INK4Aand p14ARFGene Promoter Hypermethylation as Prognostic Biomarker in Oral and Oropharyngeal Squamous Cell Carcinoma: A Review
Autor: L.W. van Bockel, Ali Al-Kaabi, S. M. Willems, A. J. Pothen
Publikováno v: Disease Markers
Disease Markers, Vol 2014 (2014)
Head and neck squamous cell carcinoma is a heterogeneous group of tumors with each subtype having a distinct histopathological and molecular profile. Most tumors share, to some extent, the same multistep carcinogenic pathways, which include a wide va
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408a85efe8ed6e5cbf3f9ff257fc7a63
https://doi.org/10.1155/2014/260549
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8
Variation in head and neck cancer care in the Netherlands: A retrospective cohort evaluation of incidence, treatment and outcome
Autor: M, de Ridder, A J M, Balm, R J, Baatenburg de Jong, C H J, Terhaard, R P, Takes, M, Slingerland, E, Dik, R J E, Sedee, J G A M, de Visscher, H, Bouman, S M, Willems, M W, Wouters, L E, Smeele, B A C, van Dijk
Publikováno v: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 43(8)
To explore variation in numbers and treatment between hospitals that treat head and neck cancer (HNC) in the Netherlands.Patient, tumor and treatment characteristics were collected from the Netherlands Cancer Registry, while histopathological feature
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e69a9ab7c1360c3a7756cfba642fc69
https://pubmed.ncbi.nlm.nih.gov/28336186
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9
Akademický článek
Diagnosis of breast lesions: fine-needle aspiration cytology or core needle biopsy? A review.
Autor: S M Willems
Publikováno v: Journal of Clinical Pathology; Apr2012, Vol. 65 Issue 4, p287-292, 6p
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10
Akademický článek
Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy.
Autor: Driehuis E; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands., Spelier S; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.; Cell Biology, Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands., Beltrán Hernández I; Pharmaceutics, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CG Utrecht, The Netherlands., de Bree R; Department of Head and Neck Surgical Oncology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., M Willems S; Department of Pathology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Clevers H; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.; Princess Maxima Center, 3584 CS Utrecht, The Netherlands., Oliveira S; Cell Biology, Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands.; Pharmaceutics, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CG Utrecht, The Netherlands.
Publikováno v: Journal of clinical medicine [J Clin Med] 2019 Nov 05; Vol. 8 (11). Date of Electronic Publication: 2019 Nov 05.
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