Zobrazeno 1 - 6
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pro vyhledávání: '"S M, Storm"'
Publikováno v:
Oncogene. 5(3)
We have determined RNA expression patterns of raf family proto-oncogenes in a variety of normal NFS/n mouse tissues, and several murine cell lines. Tissues were collected from male and female adults, and 16 day old fetuses. Raf-1 transcripts of 3.1 k
Publikováno v:
Critical reviews in oncogenesis. 2(1)
There are three active raf genes in man and at least two in Xenopus and Drosophila. The mammalian c- and A-raf genes have 16 coding exons, which span 40 and 20 kb, respectively. B-raf is larger and extends over greater than 46 kb. Human c-raf-1 maps
Publikováno v:
The Journal of Immunology. 140:3528-3533
A murine mAb, STEGI 1, was generated against a 30-kDa raf protein purified from an Escherichia coli expression vector. Immunoblot analysis confirmed that this antibody recognized the original immunizing protein as well as a 44- to 48-kDa protein from
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 140(10)
A murine mAb, STEGI 1, was generated against a 30-kDa raf protein purified from an Escherichia coli expression vector. Immunoblot analysis confirmed that this antibody recognized the original immunizing protein as well as a 44- to 48-kDa protein from
Publikováno v:
Haematology and blood transfusion. 31
Publikováno v:
Princess Takamatsu symposia. 17
raf oncogenes were shown to act synergistically with myc in transformation. The contribution of myc was identified as that of a "second messenger" in signal transduction of at least some, competence inducing, growth factors. The role of raf appears t